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CYLD CYLD lysine 63 deubiquitinase [ Canis lupus familiaris (dog) ]

Gene ID: 611649, updated on 26-Sep-2018

Summary

Official Symbol
CYLDprovided by VGNC
Official Full Name
CYLD lysine 63 deubiquitinaseprovided by VGNC
Primary source
VGNC:VGNC:50293
See related
Ensembl:ENSCAFG00000009802
Gene type
protein coding
RefSeq status
MODEL
Organism
Canis lupus familiaris (sub-species: familiaris)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs

Genomic context

See CYLD in Genome Data Viewer
Location:
chromosome: 2
Exon count:
19
Annotation release Status Assembly Chr Location
105 current CanFam3.1 (GCF_000002285.3) 2 NC_006584.3 (64561684..64628829, complement)

Chromosome 2 - NC_006584.3Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC111094685 Neighboring gene uncharacterized LOC111094689 Neighboring gene uncharacterized LOC111094690 Neighboring gene nucleotide binding oligomerization domain containing 2

Genomic regions, transcripts, and products

Genomic Sequence:
NC_006584.3 Chromosome 2 Reference CanFam3.1 Primary Assembly

Bibliography

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Pathways from BioSystems

General gene information

Homology

General protein information

Preferred Names
ubiquitin carboxyl-terminal hydrolase CYLD
XP_005617624.1
XP_005617625.1
XP_005617626.1
XP_854436.1

NCBI Reference Sequences (RefSeq)

RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 105 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference CanFam3.1 Primary Assembly

Genomic

  1. NC_006584.3 Reference CanFam3.1 Primary Assembly

    Range
    64561684..64628829 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005617567.3XP_005617624.1  ubiquitin carboxyl-terminal hydrolase CYLD isoform X1

    See identical proteins and their annotated locations for XP_005617624.1

    Conserved Domains (3) summary
    smart01052
    Location:472540
    CAP_GLY; Cytoskeleton-associated proteins (CAPs) are involved in the organisation of microtubules and transportation of vesicles and organelles along the cytoskeletal network
    cd02670
    Location:593948
    Peptidase_C19N; A subfamily of Peptidase C19. Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyze bonds involving the carboxyl ...
    pfam16607
    Location:307471
    CYLD_phos_site; Phosphorylation region of CYLD, unstructured
  2. XM_005617569.3XP_005617626.1  ubiquitin carboxyl-terminal hydrolase CYLD isoform X3

    Conserved Domains (3) summary
    smart01052
    Location:397465
    CAP_GLY; Cytoskeleton-associated proteins (CAPs) are involved in the organisation of microtubules and transportation of vesicles and organelles along the cytoskeletal network
    cd02670
    Location:518873
    Peptidase_C19N; A subfamily of Peptidase C19. Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyze bonds involving the carboxyl ...
    pfam16607
    Location:305396
    CYLD_phos_site; Phosphorylation region of CYLD, unstructured
  3. XM_005617568.3XP_005617625.1  ubiquitin carboxyl-terminal hydrolase CYLD isoform X2

    UniProtKB/TrEMBL
    E2RIB3
    Related
    ENSCAFP00000014406.3, ENSCAFT00000015568.3
    Conserved Domains (3) summary
    smart01052
    Location:469537
    CAP_GLY; Cytoskeleton-associated proteins (CAPs) are involved in the organisation of microtubules and transportation of vesicles and organelles along the cytoskeletal network
    cd02670
    Location:590945
    Peptidase_C19N; A subfamily of Peptidase C19. Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyze bonds involving the carboxyl ...
    pfam16607
    Location:304468
    CYLD_phos_site; Phosphorylation region of CYLD, unstructured
  4. XM_849343.5XP_854436.1  ubiquitin carboxyl-terminal hydrolase CYLD isoform X1

    See identical proteins and their annotated locations for XP_854436.1

    Conserved Domains (3) summary
    smart01052
    Location:472540
    CAP_GLY; Cytoskeleton-associated proteins (CAPs) are involved in the organisation of microtubules and transportation of vesicles and organelles along the cytoskeletal network
    cd02670
    Location:593948
    Peptidase_C19N; A subfamily of Peptidase C19. Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyze bonds involving the carboxyl ...
    pfam16607
    Location:307471
    CYLD_phos_site; Phosphorylation region of CYLD, unstructured
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