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GEM GTP binding protein overexpressed in skeletal muscle [ Canis lupus familiaris (dog) ]

Gene ID: 611634, updated on 25-Jul-2026
Official Symbol
GEMprovided by VGNC
Official Full Name
GTP binding protein overexpressed in skeletal muscleprovided by VGNC
Primary source
VGNC:VGNC:41172
See related
Ensembl:ENSCAFG00845014817 RGD:12163518
Gene type
protein coding
RefSeq status
MODEL
Organism
Canis lupus familiaris
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs
all
Try the new Gene page
Try the new Transcripts and proteins table
See GEM in Genome Data Viewer
Location:
chromosome: 29
Exon count:
7
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) 29 NC_051833.1 (39220477..39241164, complement)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 29 NC_006611.4 (39177842..39199013, complement)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 29 NC_049250.1 (39670894..39692020, complement)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) 29 NC_049289.1 (39234088..39255249, complement)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 29 NC_049770.1 (39229276..39250433, complement)

Chromosome 29 - NC_051833.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC119866691 Neighboring gene cadherin 17 Neighboring gene uncharacterized LOC102152572 Neighboring gene uncharacterized LOC111093215

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables GTP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables GTPase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables calcium channel regulator activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in negative regulation of high voltage-gated calcium channel activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 
Preferred Names
GTP-binding protein GEM
XP_005638187.1
XP_013964797.1
XP_022268060.1
XP_038297553.1
XP_038297554.1
XP_038297555.1
XP_038297556.1
XP_038372126.1
XP_038372127.1
XP_038372128.1
XP_038372129.1
XP_038435697.1
XP_038435698.1
XP_038435699.1
XP_038435700.1
XP_038499933.1
XP_038499934.1
XP_038499935.1
XP_038499936.1
XP_854414.2

NEW Try the new Transcript table

RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051833.1 Reference ROS_Cfam_1.0

    Range
    39220477..39241164 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038441627.1 → XP_038297555.1  GTP-binding protein GEM isoform X2

    UniProtKB/TrEMBL
    A0A8C0KDX8
    Conserved Domains (1) summary
    cl38936
    Location:76 → 215
    P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases

  2. XM_038441628.1 → XP_038297556.1  GTP-binding protein GEM isoform X2

    UniProtKB/TrEMBL
    A0A8C0KDX8
    Conserved Domains (1) summary
    cl38936
    Location:76 → 215
    P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases

  3. XM_038441625.1 → XP_038297553.1  GTP-binding protein GEM isoform X1

    UniProtKB/TrEMBL
    A0A8C0KDJ9, A0A8I3NVP2
    Conserved Domains (1) summary
    cd04148
    Location:76 → 296
    RGK; Rem, Rem2, Rad, Gem/Kir (RGK) subfamily of Ras GTPases

  4. XM_038441626.1 → XP_038297554.1  GTP-binding protein GEM isoform X1

    UniProtKB/TrEMBL
    A0A8C0KDJ9, A0A8I3NVP2
    Related
    ENSCAFP00845020873.1, ENSCAFT00845026483.1
    Conserved Domains (1) summary
    cd04148
    Location:76 → 296
    RGK; Rem, Rem2, Rad, Gem/Kir (RGK) subfamily of Ras GTPases

RNA

  1. XR_005304432.1 RNA Sequence

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049289.1 Alternate UMICH_Zoey_3.1

    Range
    39234088..39255249 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038516200.1 → XP_038372128.1  

    Conserved Domains (1) summary
    cl38936
    Location:76 → 215
    P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases

  2. XM_038516201.1 → XP_038372129.1  

    Conserved Domains (1) summary
    cl38936
    Location:76 → 215
    P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases

  3. XM_038516198.1 → XP_038372126.1  

    Conserved Domains (1) summary
    cd04148
    Location:76 → 296
    RGK; Rem, Rem2, Rad, Gem/Kir (RGK) subfamily of Ras GTPases

  4. XM_038516199.1 → XP_038372127.1  

    Conserved Domains (1) summary
    cd04148
    Location:76 → 296
    RGK; Rem, Rem2, Rad, Gem/Kir (RGK) subfamily of Ras GTPases

RNA

  1. XR_005347478.1 RNA Sequence

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049770.1 Alternate UNSW_CanFamBas_1.0

    Range
    39229276..39250433 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038644007.1 → XP_038499935.1  

    Conserved Domains (1) summary
    cl38936
    Location:76 → 215
    P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases

  2. XM_038644008.1 → XP_038499936.1  

    Conserved Domains (1) summary
    cl38936
    Location:76 → 215
    P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases

  3. XM_038644005.1 → XP_038499933.1  

    Conserved Domains (1) summary
    cd04148
    Location:76 → 296
    RGK; Rem, Rem2, Rad, Gem/Kir (RGK) subfamily of Ras GTPases

  4. XM_038644006.1 → XP_038499934.1  

    Conserved Domains (1) summary
    cd04148
    Location:76 → 296
    RGK; Rem, Rem2, Rad, Gem/Kir (RGK) subfamily of Ras GTPases

RNA

  1. XR_005415067.1 RNA Sequence

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049250.1 Alternate UU_Cfam_GSD_1.0

    Range
    39670894..39692020 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038579771.1 → XP_038435699.1  GTP-binding protein GEM isoform X2

  2. XM_038579772.1 → XP_038435700.1  GTP-binding protein GEM isoform X2

  3. XM_038579769.1 → XP_038435697.1  GTP-binding protein GEM isoform X1

    UniProtKB/TrEMBL
    A0A8C0KDJ9, A0A8I3NVP2
    Conserved Domains (1) summary
    cd04148
    Location:76 → 296
    RGK; Rem, Rem2, Rad, Gem/Kir (RGK) subfamily of Ras GTPases

  4. XM_038579770.1 → XP_038435698.1  GTP-binding protein GEM isoform X1

    UniProtKB/TrEMBL
    A0A8C0KDJ9, A0A8I3NVP2
    Conserved Domains (1) summary
    cd04148
    Location:76 → 296
    RGK; Rem, Rem2, Rad, Gem/Kir (RGK) subfamily of Ras GTPases

RNA

  1. XR_005381245.1 RNA Sequence

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006611.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    39177842..39199013 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_014109322.3 → XP_013964797.1  GTP-binding protein GEM isoform X2

    Conserved Domains (1) summary
    cl21455
    Location:76 → 215
    P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases

  2. XM_022412352.2 → XP_022268060.1  GTP-binding protein GEM isoform X2

    Conserved Domains (1) summary
    cl21455
    Location:76 → 215
    P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases

  3. XM_849321.6 → XP_854414.2  GTP-binding protein GEM isoform X1

    See identical proteins and their annotated locations for XP_854414.2

    UniProtKB/TrEMBL
    A0A8C0KDJ9, A0A8I3NVP2
    Conserved Domains (1) summary
    cd04148
    Location:76 → 296
    RGK; Rem, Rem2, Rad, Gem/Kir (RGK) subfamily of Ras GTPases

  4. XM_005638130.4 → XP_005638187.1  GTP-binding protein GEM isoform X1

    See identical proteins and their annotated locations for XP_005638187.1

    UniProtKB/TrEMBL
    A0A8C0KDJ9, A0A8I3NVP2
    Conserved Domains (1) summary
    cd04148
    Location:76 → 296
    RGK; Rem, Rem2, Rad, Gem/Kir (RGK) subfamily of Ras GTPases

RNA

  1. XR_002620939.2 RNA Sequence

Nucleotide Protein
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