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MCOLN1 mucolipin TRP cation channel 1 [ Canis lupus familiaris (dog) ]

Gene ID: 611517, updated on 27-Jun-2026
Official Symbol
MCOLN1provided by VGNC
Official Full Name
mucolipin TRP cation channel 1provided by VGNC
Primary source
VGNC:VGNC:43090
See related
Ensembl:ENSCAFG00845025665 RGD:12351132
Gene type
protein coding
RefSeq status
MODEL
Organism
Canis lupus familiaris (sub-species: familiaris)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs
all
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Try the new Transcripts and proteins table
See MCOLN1 in Genome Data Viewer
Location:
chromosome: 20
Exon count:
14
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) 20 NC_051824.1 (52847692..52856522)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 20 NC_006602.4 (52122621..52131450)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 20 NC_049241.1 (52726054..52734883)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) 20 NC_049280.1 (52051554..52060343)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 20 NC_049761.1 (52495158..52503986)

Chromosome 20 - NC_051824.1Genomic Context describing neighboring genes Neighboring gene small nucleolar RNA U13 Neighboring gene zinc finger protein 358 Neighboring gene patatin like phospholipase domain containing 6 Neighboring gene uncharacterized LOC119864757 Neighboring gene calmodulin regulated spectrin associated protein family member 3 Neighboring gene XPA binding protein 2

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables NAADP-sensitive calcium-release channel activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in lysosomal membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 
Preferred Names
mucolipin-1
Names
mucolipin 1
XP_038360306.1

Length

  • 577

NEW Try the new Transcript table

RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051824.1 Reference ROS_Cfam_1.0

    Range
    52847692..52856522
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038428743.1 → XP_038284671.1  mucolipin-1 isoform X1

    UniProtKB/TrEMBL
    A0A8C0LEB6, A0A8C0LG30
    Related
    ENSCAFP00845035534.1, ENSCAFT00845045309.1
    Conserved Domains (2) summary
    pfam08016
    Location:385 → 521
    PKD_channel; Polycystin cation channel
    cd21070
    Location:109 → 289
    ELD_TRPML1; extracytosolic/lumenal domain (ELD) found in transient receptor potential channel mucolipin 1 (TRPML1)

  2. XM_038428744.1 → XP_038284672.1  mucolipin-1 isoform X2

    UniProtKB/TrEMBL
    A0A8C0LG30
    Conserved Domains (2) summary
    pfam08016
    Location:250 → 452
    PKD_channel; Polycystin cation channel
    cl41763
    Location:109 → 256
    ELD_TRPML; extracytosolic/lumenal domain (ELD) found in transient receptor potential channel mucolipins (TRPMLs)

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049280.1 Alternate UMICH_Zoey_3.1

    Range
    52051554..52060343
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038504378.1 → XP_038360306.1  

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049761.1 Alternate UNSW_CanFamBas_1.0

    Range
    52495158..52503986
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038631569.1 → XP_038487497.1  

    Conserved Domains (2) summary
    pfam08016
    Location:385 → 521
    PKD_channel; Polycystin cation channel
    cd21070
    Location:109 → 289
    ELD_TRPML1; extracytosolic/lumenal domain (ELD) found in transient receptor potential channel mucolipin 1 (TRPML1)

  2. XM_038631570.1 → XP_038487498.1  

    Conserved Domains (2) summary
    pfam08016
    Location:250 → 452
    PKD_channel; Polycystin cation channel
    cl41763
    Location:109 → 256
    ELD_TRPML; extracytosolic/lumenal domain (ELD) found in transient receptor potential channel mucolipins (TRPMLs)

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049241.1 Alternate UU_Cfam_GSD_1.0

    Range
    52726054..52734883
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038567419.1 → XP_038423347.1  mucolipin-1 isoform X1

    UniProtKB/TrEMBL
    A0A8C0LEB6, A0A8C0LG30
    Conserved Domains (2) summary
    pfam08016
    Location:385 → 521
    PKD_channel; Polycystin cation channel
    cd21070
    Location:109 → 289
    ELD_TRPML1; extracytosolic/lumenal domain (ELD) found in transient receptor potential channel mucolipin 1 (TRPML1)

  2. XM_038567421.1 → XP_038423349.1  mucolipin-1 isoform X2

    UniProtKB/TrEMBL
    A0A8C0LG30
    Conserved Domains (2) summary
    pfam08016
    Location:250 → 452
    PKD_channel; Polycystin cation channel
    cl41763
    Location:109 → 256
    ELD_TRPML; extracytosolic/lumenal domain (ELD) found in transient receptor potential channel mucolipins (TRPMLs)

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006602.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    52122621..52131450
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_849191.6 → XP_854284.1  mucolipin-1 isoform X1

    UniProtKB/TrEMBL
    A0A8C0LEB6, A0A8C0LG30
    Conserved Domains (2) summary
    pfam08016
    Location:385 → 521
    PKD_channel; Polycystin cation channel
    cd21070
    Location:109 → 289
    ELD_TRPML1; extracytosolic/lumenal domain (ELD) found in transient receptor potential channel mucolipin 1 (TRPML1)

  2. XM_022407095.2 → XP_022262803.1  mucolipin-1 isoform X2

    UniProtKB/TrEMBL
    A0A8C0LG30
    Conserved Domains (2) summary
    pfam08016
    Location:250 → 452
    PKD_channel; Polycystin cation channel
    cl41763
    Location:109 → 256
    ELD_TRPML; extracytosolic/lumenal domain (ELD) found in transient receptor potential channel mucolipins (TRPMLs)
Nucleotide Protein
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