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LOC611363 mesothelin [ Canis lupus familiaris (dog) ]

Gene ID: 611363, updated on 27-Jun-2026
Gene symbol
LOC611363
Gene description
mesothelin
See related
Ensembl:ENSCAFG00845025947 RGD:12394296
Gene type
protein coding
RefSeq status
MODEL
Organism
Canis lupus familiaris (sub-species: familiaris)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Also known as
MSLN
Try the new Gene page
Try the new Transcripts and proteins table
See LOC611363 in Genome Data Viewer
Location:
chromosome: 6
Exon count:
13
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) 6 NC_051810.1 (40171101..40175067, complement)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 6 NC_006588.4 (41092644..41096610, complement)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 6 NC_049227.1 (40298820..40302786, complement)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) 6 NC_049266.1 (39859730..39863696, complement)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 6 NC_049747.1 (39819938..39823904, complement)

Chromosome 6 - NC_051810.1Genomic Context describing neighboring genes Neighboring gene RNA pseudouridine synthase domain containing 1 Neighboring gene mesothelin-like Neighboring gene uncharacterized LOC111096335 Neighboring gene cytosolic iron-sulfur assembly component 3

Gene Ontology Provided by RefSeq

Process Evidence Code Pubs
involved_in cell-matrix adhesion IEA
Inferred from Electronic Annotation
more info
PubMed 
Component Evidence Code Pubs
located_in cell surface IEA
Inferred from Electronic Annotation
more info
PubMed 
Preferred Names
mesothelin

NEW Try the new Transcript table

RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051810.1 Reference ROS_Cfam_1.0

    Range
    40171101..40175067 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038669685.1XP_038525613.1  mesothelin isoform X8

    UniProtKB/TrEMBL
    A0A8C0K9C4
    Conserved Domains (1) summary
    pfam06060
    Location:44411
    Mesothelin; Pre-pro-megakaryocyte potentiating factor precursor (Mesothelin)
  2. XM_038669683.1XP_038525611.1  mesothelin isoform X7

    UniProtKB/TrEMBL
    A0A8C0K4W0
    Conserved Domains (1) summary
    pfam06060
    Location:80418
    Mesothelin; Pre-pro-megakaryocyte potentiating factor precursor (Mesothelin)
  3. XM_038669682.1XP_038525610.1  mesothelin isoform X6

    UniProtKB/TrEMBL
    A0A8C0K4W0, A0A8I3PN01
    Related
    ENSCAFP00845035949.1, ENSCAFT00845045797.1
    Conserved Domains (1) summary
    pfam06060
    Location:80423
    Mesothelin; Pre-pro-megakaryocyte potentiating factor precursor (Mesothelin)
  4. XM_038669681.1XP_038525609.1  mesothelin isoform X5

    UniProtKB/TrEMBL
    A0A8C0K4W0
    Conserved Domains (1) summary
    pfam06060
    Location:80424
    Mesothelin; Pre-pro-megakaryocyte potentiating factor precursor (Mesothelin)
  5. XM_038669680.1XP_038525608.1  mesothelin isoform X4

    Conserved Domains (1) summary
    pfam06060
    Location:80426
    Mesothelin; Pre-pro-megakaryocyte potentiating factor precursor (Mesothelin)
  6. XM_038669678.1XP_038525606.1  mesothelin isoform X2

    Conserved Domains (1) summary
    pfam06060
    Location:80446
    Mesothelin; Pre-pro-megakaryocyte potentiating factor precursor (Mesothelin)
  7. XM_038669679.1XP_038525607.1  mesothelin isoform X3

    Conserved Domains (1) summary
    pfam06060
    Location:80427
    Mesothelin; Pre-pro-megakaryocyte potentiating factor precursor (Mesothelin)
  8. XM_038669677.1XP_038525605.1  mesothelin isoform X1

    Conserved Domains (1) summary
    pfam06060
    Location:80447
    Mesothelin; Pre-pro-megakaryocyte potentiating factor precursor (Mesothelin)
  9. XM_038669684.1XP_038525612.1  mesothelin isoform X8

    UniProtKB/TrEMBL
    A0A8C0K9C4
    Conserved Domains (1) summary
    pfam06060
    Location:44411
    Mesothelin; Pre-pro-megakaryocyte potentiating factor precursor (Mesothelin)

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049266.1 Alternate UMICH_Zoey_3.1

    Range
    39859730..39863696 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038479611.1XP_038335539.1  

    Conserved Domains (1) summary
    pfam06060
    Location:44411
    Mesothelin; Pre-pro-megakaryocyte potentiating factor precursor (Mesothelin)
  2. XM_038479609.1XP_038335537.1  

    Conserved Domains (1) summary
    pfam06060
    Location:80418
    Mesothelin; Pre-pro-megakaryocyte potentiating factor precursor (Mesothelin)
  3. XM_038479608.1XP_038335536.1  

    Conserved Domains (1) summary
    pfam06060
    Location:80423
    Mesothelin; Pre-pro-megakaryocyte potentiating factor precursor (Mesothelin)
  4. XM_038479606.1XP_038335534.1  

    Conserved Domains (1) summary
    pfam06060
    Location:80424
    Mesothelin; Pre-pro-megakaryocyte potentiating factor precursor (Mesothelin)
  5. XM_038479605.1XP_038335533.1  

    Conserved Domains (1) summary
    pfam06060
    Location:80426
    Mesothelin; Pre-pro-megakaryocyte potentiating factor precursor (Mesothelin)
  6. XM_038479603.1XP_038335531.1  

    Conserved Domains (1) summary
    pfam06060
    Location:80446
    Mesothelin; Pre-pro-megakaryocyte potentiating factor precursor (Mesothelin)
  7. XM_038479604.1XP_038335532.1  

    Conserved Domains (1) summary
    pfam06060
    Location:80427
    Mesothelin; Pre-pro-megakaryocyte potentiating factor precursor (Mesothelin)
  8. XM_038479602.1XP_038335530.1  

    Conserved Domains (1) summary
    pfam06060
    Location:80447
    Mesothelin; Pre-pro-megakaryocyte potentiating factor precursor (Mesothelin)
  9. XM_038479610.1XP_038335538.1  

    Conserved Domains (1) summary
    pfam06060
    Location:44411
    Mesothelin; Pre-pro-megakaryocyte potentiating factor precursor (Mesothelin)

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049747.1 Alternate UNSW_CanFamBas_1.0

    Range
    39819938..39823904 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038605009.1XP_038460937.1  

    Conserved Domains (1) summary
    pfam06060
    Location:44411
    Mesothelin; Pre-pro-megakaryocyte potentiating factor precursor (Mesothelin)
  2. XM_038605007.1XP_038460935.1  

    Conserved Domains (1) summary
    pfam06060
    Location:80418
    Mesothelin; Pre-pro-megakaryocyte potentiating factor precursor (Mesothelin)
  3. XM_038605006.1XP_038460934.1  

    Conserved Domains (1) summary
    pfam06060
    Location:80423
    Mesothelin; Pre-pro-megakaryocyte potentiating factor precursor (Mesothelin)
  4. XM_038605005.1XP_038460933.1  

    Conserved Domains (1) summary
    pfam06060
    Location:80424
    Mesothelin; Pre-pro-megakaryocyte potentiating factor precursor (Mesothelin)
  5. XM_038605003.1XP_038460931.1  

    Conserved Domains (1) summary
    pfam06060
    Location:80426
    Mesothelin; Pre-pro-megakaryocyte potentiating factor precursor (Mesothelin)
  6. XM_038605001.1XP_038460929.1  

    Conserved Domains (1) summary
    pfam06060
    Location:80446
    Mesothelin; Pre-pro-megakaryocyte potentiating factor precursor (Mesothelin)
  7. XM_038605002.1XP_038460930.1  

    Conserved Domains (1) summary
    pfam06060
    Location:80427
    Mesothelin; Pre-pro-megakaryocyte potentiating factor precursor (Mesothelin)
  8. XM_038605000.1XP_038460928.1  

    Conserved Domains (1) summary
    pfam06060
    Location:80447
    Mesothelin; Pre-pro-megakaryocyte potentiating factor precursor (Mesothelin)
  9. XM_038605008.1XP_038460936.1  

    Conserved Domains (1) summary
    pfam06060
    Location:44411
    Mesothelin; Pre-pro-megakaryocyte potentiating factor precursor (Mesothelin)

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049227.1 Alternate UU_Cfam_GSD_1.0

    Range
    40298820..40302786 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038540885.1XP_038396813.1  mesothelin isoform X8

    UniProtKB/TrEMBL
    A0A8C0K9C4
    Conserved Domains (1) summary
    pfam06060
    Location:44411
    Mesothelin; Pre-pro-megakaryocyte potentiating factor precursor (Mesothelin)
  2. XM_038540883.1XP_038396811.1  mesothelin isoform X7

    UniProtKB/TrEMBL
    A0A8C0K4W0
    Conserved Domains (1) summary
    pfam06060
    Location:80418
    Mesothelin; Pre-pro-megakaryocyte potentiating factor precursor (Mesothelin)
  3. XM_038540882.1XP_038396810.1  mesothelin isoform X6

    UniProtKB/TrEMBL
    A0A8C0K4W0, A0A8I3PN01
    Conserved Domains (1) summary
    pfam06060
    Location:80423
    Mesothelin; Pre-pro-megakaryocyte potentiating factor precursor (Mesothelin)
  4. XM_038540881.1XP_038396809.1  mesothelin isoform X5

    UniProtKB/TrEMBL
    A0A8C0K4W0
    Conserved Domains (1) summary
    pfam06060
    Location:80424
    Mesothelin; Pre-pro-megakaryocyte potentiating factor precursor (Mesothelin)
  5. XM_038540880.1XP_038396808.1  mesothelin isoform X4

    Conserved Domains (1) summary
    pfam06060
    Location:80426
    Mesothelin; Pre-pro-megakaryocyte potentiating factor precursor (Mesothelin)
  6. XM_038540877.1XP_038396805.1  mesothelin isoform X2

    Conserved Domains (1) summary
    pfam06060
    Location:80446
    Mesothelin; Pre-pro-megakaryocyte potentiating factor precursor (Mesothelin)
  7. XM_038540879.1XP_038396807.1  mesothelin isoform X3

    Conserved Domains (1) summary
    pfam06060
    Location:80427
    Mesothelin; Pre-pro-megakaryocyte potentiating factor precursor (Mesothelin)
  8. XM_038540876.1XP_038396804.1  mesothelin isoform X1

    Conserved Domains (1) summary
    pfam06060
    Location:80447
    Mesothelin; Pre-pro-megakaryocyte potentiating factor precursor (Mesothelin)
  9. XM_038540884.1XP_038396812.1  mesothelin isoform X8

    UniProtKB/TrEMBL
    A0A8C0K9C4
    Conserved Domains (1) summary
    pfam06060
    Location:44411
    Mesothelin; Pre-pro-megakaryocyte potentiating factor precursor (Mesothelin)

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006588.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    41092644..41096610 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038551016.1XP_038406944.1  mesothelin isoform X8

    UniProtKB/TrEMBL
    A0A8C0K9C4
    Conserved Domains (1) summary
    pfam06060
    Location:44411
    Mesothelin; Pre-pro-megakaryocyte potentiating factor precursor (Mesothelin)
  2. XM_038550997.1XP_038406925.1  mesothelin isoform X7

    UniProtKB/TrEMBL
    A0A8C0K4W0
    Conserved Domains (1) summary
    pfam06060
    Location:80418
    Mesothelin; Pre-pro-megakaryocyte potentiating factor precursor (Mesothelin)
  3. XM_022420288.2XP_022275996.1  mesothelin isoform X6

    UniProtKB/TrEMBL
    A0A8C0K4W0, A0A8I3PN01
    Conserved Domains (1) summary
    pfam06060
    Location:80423
    Mesothelin; Pre-pro-megakaryocyte potentiating factor precursor (Mesothelin)
  4. XM_038550989.1XP_038406917.1  mesothelin isoform X5

    UniProtKB/TrEMBL
    A0A8C0K4W0
    Conserved Domains (1) summary
    pfam06060
    Location:80424
    Mesothelin; Pre-pro-megakaryocyte potentiating factor precursor (Mesothelin)
  5. XM_022420287.2XP_022275995.1  mesothelin isoform X4

    Conserved Domains (1) summary
    pfam06060
    Location:80426
    Mesothelin; Pre-pro-megakaryocyte potentiating factor precursor (Mesothelin)
  6. XM_022420286.2XP_022275994.1  mesothelin isoform X2

    Conserved Domains (1) summary
    pfam06060
    Location:80446
    Mesothelin; Pre-pro-megakaryocyte potentiating factor precursor (Mesothelin)
  7. XM_038550978.1XP_038406906.1  mesothelin isoform X3

    Conserved Domains (1) summary
    pfam06060
    Location:80427
    Mesothelin; Pre-pro-megakaryocyte potentiating factor precursor (Mesothelin)
  8. XM_038550957.1XP_038406885.1  mesothelin isoform X1

    Conserved Domains (1) summary
    pfam06060
    Location:80447
    Mesothelin; Pre-pro-megakaryocyte potentiating factor precursor (Mesothelin)
  9. XM_038551007.1XP_038406935.1  mesothelin isoform X8

    UniProtKB/TrEMBL
    A0A8C0K9C4
    Conserved Domains (1) summary
    pfam06060
    Location:44411
    Mesothelin; Pre-pro-megakaryocyte potentiating factor precursor (Mesothelin)