WDR1 WD repeat domain 1 [Canis lupus familiaris (dog)] - Gene

Summary

Official Symbol: WDR1provided by VGNC
Official Full Name: WD repeat domain 1provided by VGNC
Primary source: VGNC:VGNC:48349
See related: Ensembl:ENSCAFG00845002747 RGD:12324347
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Canis lupus familiaris
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs: all
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Genomic context

Location:: chromosome: 3

Exon count:: 15

Annotation release	Status	Assembly	Chr	Location
106	current	ROS_Cfam_1.0 (GCF_014441545.1)	3	NC_051807.1 (70061466..70103927)
106	current	Dog10K_Boxer_Tasha (GCF_000002285.5)	3	NC_006585.4 (71858411..71900857)
106	current	UU_Cfam_GSD_1.0 (GCF_011100685.1)	3	NC_049224.1 (69883812..69926328)
106	current	UMICH_Zoey_3.1 (GCF_005444595.1)	3	NC_049263.1 (69335607..69378040)
106	current	UNSW_CanFamBas_1.0 (GCF_013276365.1)	3	NC_049744.1 (69500585..69543019)

Chromosome 3 - NC_051807.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables actin filament binding	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in actin filament depolymerization	IEA Inferred from Electronic Annotation more info	PubMed
involved_in locomotion	IEA Inferred from Electronic Annotation more info	PubMed
involved_in positive regulation of actin filament depolymerization	IEA Inferred from Electronic Annotation more info	PubMed
involved_in sarcomere organization	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in cortical actin cytoskeleton	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: WD repeat-containing protein 1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001130837.2 → NP_001124309.1 WD repeat-containing protein 1

See identical proteins and their annotated locations for NP_001124309.1

Status: VALIDATED

Source sequence(s)

BU744582, CO708699, DN368115, DN383313, DN424234, DN427984, DN431902, DN875164

UniProtKB/TrEMBL

A0A5K1UTD0, A0A8C0KDE7, A0A8I3MMG9, A0A8I3MUB7

Related

ENSCAFP00845003957.1, ENSCAFT00845004963.1

Conserved Domains (3) summary

cd00200
Location:50 → 389

WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

sd00039
Location:62 → 100

7WD40; WD40 repeat [structural motif]

cl25539
Location:312 → 602

WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...