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ADAP2 ArfGAP with dual PH domains 2 [ Canis lupus familiaris (dog) ]

Gene ID: 610782, updated on 25-Jul-2026
Official Symbol
ADAP2provided by VGNC
Official Full Name
ArfGAP with dual PH domains 2provided by VGNC
Primary source
VGNC:VGNC:37611
See related
Ensembl:ENSCAFG00845013471 RGD:12382687
Gene type
protein coding
RefSeq status
MODEL
Organism
Canis lupus familiaris
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Also known as
CENTA2
Orthologs
all
Try the new Gene page
Try the new Transcripts and proteins table
See ADAP2 in Genome Data Viewer
Location:
chromosome: 9
Exon count:
15
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) 9 NC_051813.1 (41617915..41661889, complement)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 9 NC_006591.4 (39960027..40003994, complement)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 9 NC_049230.1 (40772613..40816629, complement)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) 9 NC_049269.1 (40403473..40447443, complement)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 9 NC_049750.1 (40697716..40742096, complement)

Chromosome 9 - NC_051813.1Genomic Context describing neighboring genes Neighboring gene ras homolog family member T1 Neighboring gene solute carrier family 25 member 39-like Neighboring gene ring finger protein 135 Neighboring gene uncharacterized LOC119873323 Neighboring gene transcription elongation factor, mitochondrial Neighboring gene ATPase family AAA domain containing 5

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables GTPase activator activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables phosphatidylinositol bisphosphate binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in positive regulation of GTPase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in intracellular membrane-bounded organelle IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 
Preferred Names
arf-GAP with dual PH domain-containing protein 2
Names
centaurin, alpha 2

NEW Try the new Transcript table

RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051813.1 Reference ROS_Cfam_1.0

    Range
    41617915..41661889 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038677386.1 → XP_038533314.1  arf-GAP with dual PH domain-containing protein 2 isoform X2

    UniProtKB/TrEMBL
    A0A8I3NR13
    Conserved Domains (3) summary
    cd01251
    Location:255 → 362
    PH2_ADAP; ArfGAP with dual PH domains Pleckstrin homology (PH) domain, repeat 2
    cd13252
    Location:133 → 241
    PH1_ADAP; ArfGAP with dual PH domains Pleckstrin homology (PH) domain, repeat 1
    cd08844
    Location:4 → 117
    ArfGap_ADAP2; ADAP2 GTPase activating protein for Arf, with dual PH domains

  2. XM_038677389.1 → XP_038533317.1  arf-GAP with dual PH domain-containing protein 2 isoform X5

    UniProtKB/TrEMBL
    A0A8C0KQ48
    Conserved Domains (3) summary
    cd01251
    Location:206 → 313
    PH2_ADAP; ArfGAP with dual PH domains Pleckstrin homology (PH) domain, repeat 2
    cl28907
    Location:4 → 117
    ArfGap; GTPase-activating protein (GAP) for the ADP ribosylation factors (ARFs)
    cl17171
    Location:133 → 192
    PH-like; Pleckstrin homology-like domain

  3. XM_038677388.1 → XP_038533316.1  arf-GAP with dual PH domain-containing protein 2 isoform X4

    UniProtKB/TrEMBL
    A0A8C0KQ48
    Conserved Domains (3) summary
    cd01251
    Location:227 → 334
    PH2_ADAP; ArfGAP with dual PH domains Pleckstrin homology (PH) domain, repeat 2
    cd13252
    Location:133 → 219
    PH1_ADAP; ArfGAP with dual PH domains Pleckstrin homology (PH) domain, repeat 1
    cd08844
    Location:4 → 117
    ArfGap_ADAP2; ADAP2 GTPase activating protein for Arf, with dual PH domains

  4. XM_038677385.1 → XP_038533313.1  arf-GAP with dual PH domain-containing protein 2 isoform X1

    UniProtKB/TrEMBL
    A0A8C0KQ48, A0A8I3S047
    Related
    ENSCAFP00845018875.1, ENSCAFT00845024031.1
    Conserved Domains (3) summary
    cd01251
    Location:255 → 362
    PH2_ADAP; ArfGAP with dual PH domains Pleckstrin homology (PH) domain, repeat 2
    cd13252
    Location:133 → 241
    PH1_ADAP; ArfGAP with dual PH domains Pleckstrin homology (PH) domain, repeat 1
    cd08844
    Location:4 → 117
    ArfGap_ADAP2; ADAP2 GTPase activating protein for Arf, with dual PH domains

  5. XM_038677387.1 → XP_038533315.1  arf-GAP with dual PH domain-containing protein 2 isoform X3

    UniProtKB/TrEMBL
    A0A8C0KQ48
    Related
    ENSCAFP00845018846.1, ENSCAFT00845023998.1
    Conserved Domains (3) summary
    cd01251
    Location:255 → 362
    PH2_ADAP; ArfGAP with dual PH domains Pleckstrin homology (PH) domain, repeat 2
    cd13252
    Location:133 → 241
    PH1_ADAP; ArfGAP with dual PH domains Pleckstrin homology (PH) domain, repeat 1
    cd08844
    Location:4 → 117
    ArfGap_ADAP2; ADAP2 GTPase activating protein for Arf, with dual PH domains

  6. XM_038677390.1 → XP_038533318.1  arf-GAP with dual PH domain-containing protein 2 isoform X6

    Conserved Domains (3) summary
    cd01251
    Location:179 → 286
    PH2_ADAP; ArfGAP with dual PH domains Pleckstrin homology (PH) domain, repeat 2
    cd13252
    Location:57 → 165
    PH1_ADAP; ArfGAP with dual PH domains Pleckstrin homology (PH) domain, repeat 1
    cl28907
    Location:1 → 41
    ArfGap; GTPase-activating protein (GAP) for the ADP ribosylation factors (ARFs)

  7. XM_038677392.1 → XP_038533320.1  arf-GAP with dual PH domain-containing protein 2 isoform X6

    Conserved Domains (3) summary
    cd01251
    Location:179 → 286
    PH2_ADAP; ArfGAP with dual PH domains Pleckstrin homology (PH) domain, repeat 2
    cd13252
    Location:57 → 165
    PH1_ADAP; ArfGAP with dual PH domains Pleckstrin homology (PH) domain, repeat 1
    cl28907
    Location:1 → 41
    ArfGap; GTPase-activating protein (GAP) for the ADP ribosylation factors (ARFs)

  8. XM_038677391.1 → XP_038533319.1  arf-GAP with dual PH domain-containing protein 2 isoform X6

    Conserved Domains (3) summary
    cd01251
    Location:179 → 286
    PH2_ADAP; ArfGAP with dual PH domains Pleckstrin homology (PH) domain, repeat 2
    cd13252
    Location:57 → 165
    PH1_ADAP; ArfGAP with dual PH domains Pleckstrin homology (PH) domain, repeat 1
    cl28907
    Location:1 → 41
    ArfGap; GTPase-activating protein (GAP) for the ADP ribosylation factors (ARFs)

RNA

  1. XR_005432456.1 RNA Sequence

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049269.1 Alternate UMICH_Zoey_3.1

    Range
    40403473..40447443 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038486331.1 → XP_038342259.1  

    Conserved Domains (3) summary
    cd01251
    Location:255 → 362
    PH2_ADAP; ArfGAP with dual PH domains Pleckstrin homology (PH) domain, repeat 2
    cd13252
    Location:133 → 241
    PH1_ADAP; ArfGAP with dual PH domains Pleckstrin homology (PH) domain, repeat 1
    cd08844
    Location:4 → 117
    ArfGap_ADAP2; ADAP2 GTPase activating protein for Arf, with dual PH domains

  2. XM_038486334.1 → XP_038342262.1  

  3. XM_038486333.1 → XP_038342261.1  

  4. XM_038486330.1 → XP_038342258.1  

  5. XM_038486332.1 → XP_038342260.1  

  6. XM_038486335.1 → XP_038342263.1  

    Conserved Domains (3) summary
    cd01251
    Location:179 → 286
    PH2_ADAP; ArfGAP with dual PH domains Pleckstrin homology (PH) domain, repeat 2
    cd13252
    Location:57 → 165
    PH1_ADAP; ArfGAP with dual PH domains Pleckstrin homology (PH) domain, repeat 1
    cl28907
    Location:1 → 41
    ArfGap; GTPase-activating protein (GAP) for the ADP ribosylation factors (ARFs)

  7. XM_038486339.1 → XP_038342267.1  

    Conserved Domains (3) summary
    cd01251
    Location:179 → 286
    PH2_ADAP; ArfGAP with dual PH domains Pleckstrin homology (PH) domain, repeat 2
    cd13252
    Location:57 → 165
    PH1_ADAP; ArfGAP with dual PH domains Pleckstrin homology (PH) domain, repeat 1
    cl28907
    Location:1 → 41
    ArfGap; GTPase-activating protein (GAP) for the ADP ribosylation factors (ARFs)

  8. XM_038486336.1 → XP_038342264.1  

    Conserved Domains (3) summary
    cd01251
    Location:179 → 286
    PH2_ADAP; ArfGAP with dual PH domains Pleckstrin homology (PH) domain, repeat 2
    cd13252
    Location:57 → 165
    PH1_ADAP; ArfGAP with dual PH domains Pleckstrin homology (PH) domain, repeat 1
    cl28907
    Location:1 → 41
    ArfGap; GTPase-activating protein (GAP) for the ADP ribosylation factors (ARFs)

RNA

  1. XR_005330990.1 RNA Sequence

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049750.1 Alternate UNSW_CanFamBas_1.0

    Range
    40697716..40742096 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038612132.1 → XP_038468060.1  

  2. XM_038612135.1 → XP_038468063.1  

  3. XM_038612134.1 → XP_038468062.1  

  4. XM_038612131.1 → XP_038468059.1  

  5. XM_038612133.1 → XP_038468061.1  

  6. XM_038612136.1 → XP_038468064.1  

    Conserved Domains (3) summary
    cd01251
    Location:179 → 286
    PH2_ADAP; ArfGAP with dual PH domains Pleckstrin homology (PH) domain, repeat 2
    cd13252
    Location:57 → 165
    PH1_ADAP; ArfGAP with dual PH domains Pleckstrin homology (PH) domain, repeat 1
    cl28907
    Location:1 → 41
    ArfGap; GTPase-activating protein (GAP) for the ADP ribosylation factors (ARFs)

  7. XM_038612138.1 → XP_038468066.1  

    Conserved Domains (3) summary
    cd01251
    Location:179 → 286
    PH2_ADAP; ArfGAP with dual PH domains Pleckstrin homology (PH) domain, repeat 2
    cd13252
    Location:57 → 165
    PH1_ADAP; ArfGAP with dual PH domains Pleckstrin homology (PH) domain, repeat 1
    cl28907
    Location:1 → 41
    ArfGap; GTPase-activating protein (GAP) for the ADP ribosylation factors (ARFs)

  8. XM_038612137.1 → XP_038468065.1  

    Conserved Domains (3) summary
    cd01251
    Location:179 → 286
    PH2_ADAP; ArfGAP with dual PH domains Pleckstrin homology (PH) domain, repeat 2
    cd13252
    Location:57 → 165
    PH1_ADAP; ArfGAP with dual PH domains Pleckstrin homology (PH) domain, repeat 1
    cl28907
    Location:1 → 41
    ArfGap; GTPase-activating protein (GAP) for the ADP ribosylation factors (ARFs)

RNA

  1. XR_005399130.1 RNA Sequence

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049230.1 Alternate UU_Cfam_GSD_1.0

    Range
    40772613..40816629 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038548168.1 → XP_038404096.1  arf-GAP with dual PH domain-containing protein 2 isoform X2

    UniProtKB/TrEMBL
    A0A8C0KM34
    Conserved Domains (3) summary
    cd01251
    Location:255 → 362
    PH2_ADAP; ArfGAP with dual PH domains Pleckstrin homology (PH) domain, repeat 2
    cd13252
    Location:133 → 241
    PH1_ADAP; ArfGAP with dual PH domains Pleckstrin homology (PH) domain, repeat 1
    cd08844
    Location:4 → 117
    ArfGap_ADAP2; ADAP2 GTPase activating protein for Arf, with dual PH domains

  2. XM_038548171.1 → XP_038404099.1  arf-GAP with dual PH domain-containing protein 2 isoform X5

    UniProtKB/TrEMBL
    A0A8C0KQ48

  3. XM_038548170.1 → XP_038404098.1  arf-GAP with dual PH domain-containing protein 2 isoform X4

    UniProtKB/TrEMBL
    A0A8C0KQ48

  4. XM_038548167.1 → XP_038404095.1  arf-GAP with dual PH domain-containing protein 2 isoform X1

    UniProtKB/TrEMBL
    A0A8C0KQ48

  5. XM_038548169.1 → XP_038404097.1  arf-GAP with dual PH domain-containing protein 2 isoform X3

    UniProtKB/TrEMBL
    A0A8C0KQ48

  6. XM_038548172.1 → XP_038404100.1  arf-GAP with dual PH domain-containing protein 2 isoform X6

    Conserved Domains (3) summary
    cd01251
    Location:179 → 286
    PH2_ADAP; ArfGAP with dual PH domains Pleckstrin homology (PH) domain, repeat 2
    cd13252
    Location:57 → 165
    PH1_ADAP; ArfGAP with dual PH domains Pleckstrin homology (PH) domain, repeat 1
    cl28907
    Location:1 → 41
    ArfGap; GTPase-activating protein (GAP) for the ADP ribosylation factors (ARFs)

  7. XM_038548174.1 → XP_038404102.1  arf-GAP with dual PH domain-containing protein 2 isoform X6

    Conserved Domains (3) summary
    cd01251
    Location:179 → 286
    PH2_ADAP; ArfGAP with dual PH domains Pleckstrin homology (PH) domain, repeat 2
    cd13252
    Location:57 → 165
    PH1_ADAP; ArfGAP with dual PH domains Pleckstrin homology (PH) domain, repeat 1
    cl28907
    Location:1 → 41
    ArfGap; GTPase-activating protein (GAP) for the ADP ribosylation factors (ARFs)

  8. XM_038548173.1 → XP_038404101.1  arf-GAP with dual PH domain-containing protein 2 isoform X6

    Conserved Domains (3) summary
    cd01251
    Location:179 → 286
    PH2_ADAP; ArfGAP with dual PH domains Pleckstrin homology (PH) domain, repeat 2
    cd13252
    Location:57 → 165
    PH1_ADAP; ArfGAP with dual PH domains Pleckstrin homology (PH) domain, repeat 1
    cl28907
    Location:1 → 41
    ArfGap; GTPase-activating protein (GAP) for the ADP ribosylation factors (ARFs)

RNA

  1. XR_005364689.1 RNA Sequence

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006591.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    39960027..40003994 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038610037.1 → XP_038465965.1  arf-GAP with dual PH domain-containing protein 2 isoform X2

    UniProtKB/TrEMBL
    A0A8C0KM34
    Conserved Domains (3) summary
    cd01251
    Location:255 → 362
    PH2_ADAP; ArfGAP with dual PH domains Pleckstrin homology (PH) domain, repeat 2
    cd13252
    Location:133 → 241
    PH1_ADAP; ArfGAP with dual PH domains Pleckstrin homology (PH) domain, repeat 1
    cd08844
    Location:4 → 117
    ArfGap_ADAP2; ADAP2 GTPase activating protein for Arf, with dual PH domains

  2. XM_014116763.3 → XP_013972238.1  arf-GAP with dual PH domain-containing protein 2 isoform X5

    UniProtKB/TrEMBL
    A0A8C0KQ48
    Conserved Domains (3) summary
    cd01251
    Location:206 → 313
    PH2_ADAP; ArfGAP with dual PH domains Pleckstrin homology (PH) domain, repeat 2
    pfam01412
    Location:9 → 126
    ArfGap; Putative GTPase activating protein for Arf
    cl17171
    Location:133 → 192
    PH-like; Pleckstrin homology-like domain

  3. XM_014116762.3 → XP_013972237.1  arf-GAP with dual PH domain-containing protein 2 isoform X4

    UniProtKB/TrEMBL
    A0A8C0KQ48
    Conserved Domains (3) summary
    cd01251
    Location:227 → 334
    PH2_ADAP; ArfGAP with dual PH domains Pleckstrin homology (PH) domain, repeat 2
    cd13252
    Location:133 → 219
    PH1_ADAP; ArfGAP with dual PH domains Pleckstrin homology (PH) domain, repeat 1
    pfam01412
    Location:9 → 126
    ArfGap; Putative GTPase activating protein for Arf

  4. XM_014116760.3 → XP_013972235.1  arf-GAP with dual PH domain-containing protein 2 isoform X1

    UniProtKB/TrEMBL
    A0A8C0KQ48
    Conserved Domains (3) summary
    cd01251
    Location:255 → 362
    PH2_ADAP; ArfGAP with dual PH domains Pleckstrin homology (PH) domain, repeat 2
    cd13252
    Location:133 → 241
    PH1_ADAP; ArfGAP with dual PH domains Pleckstrin homology (PH) domain, repeat 1
    pfam01412
    Location:9 → 126
    ArfGap; Putative GTPase activating protein for Arf

  5. XM_848333.6 → XP_853426.2  arf-GAP with dual PH domain-containing protein 2 isoform X3

    UniProtKB/TrEMBL
    A0A8C0KQ48
    Conserved Domains (3) summary
    cd01251
    Location:255 → 362
    PH2_ADAP; ArfGAP with dual PH domains Pleckstrin homology (PH) domain, repeat 2
    cd13252
    Location:133 → 241
    PH1_ADAP; ArfGAP with dual PH domains Pleckstrin homology (PH) domain, repeat 1
    pfam01412
    Location:9 → 126
    ArfGap; Putative GTPase activating protein for Arf

  6. XM_022423318.2 → XP_022279026.1  arf-GAP with dual PH domain-containing protein 2 isoform X6

    Conserved Domains (3) summary
    cd01251
    Location:179 → 286
    PH2_ADAP; ArfGAP with dual PH domains Pleckstrin homology (PH) domain, repeat 2
    cd13252
    Location:57 → 165
    PH1_ADAP; ArfGAP with dual PH domains Pleckstrin homology (PH) domain, repeat 1
    cl28907
    Location:1 → 41
    ArfGap; GTPase-activating protein (GAP) for the ADP ribosylation factors (ARFs)

  7. XM_038610039.1 → XP_038465967.1  arf-GAP with dual PH domain-containing protein 2 isoform X6

    Conserved Domains (3) summary
    cd01251
    Location:179 → 286
    PH2_ADAP; ArfGAP with dual PH domains Pleckstrin homology (PH) domain, repeat 2
    cd13252
    Location:57 → 165
    PH1_ADAP; ArfGAP with dual PH domains Pleckstrin homology (PH) domain, repeat 1
    cl28907
    Location:1 → 41
    ArfGap; GTPase-activating protein (GAP) for the ADP ribosylation factors (ARFs)

  8. XM_022423319.2 → XP_022279027.1  arf-GAP with dual PH domain-containing protein 2 isoform X6

    Conserved Domains (3) summary
    cd01251
    Location:179 → 286
    PH2_ADAP; ArfGAP with dual PH domains Pleckstrin homology (PH) domain, repeat 2
    cd13252
    Location:57 → 165
    PH1_ADAP; ArfGAP with dual PH domains Pleckstrin homology (PH) domain, repeat 1
    cl28907
    Location:1 → 41
    ArfGap; GTPase-activating protein (GAP) for the ADP ribosylation factors (ARFs)

RNA

  1. XR_005398408.1 RNA Sequence

Nucleotide Protein
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