U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

TTC4 tetratricopeptide repeat domain 4 [ Canis lupus familiaris (dog) ]

Gene ID: 610555, updated on 25-Jul-2026
Official Symbol
TTC4provided by VGNC
Official Full Name
tetratricopeptide repeat domain 4provided by VGNC
Primary source
VGNC:VGNC:47959
See related
Ensembl:ENSCAFG00845014350 RGD:12272550
Gene type
protein coding
RefSeq status
MODEL
Organism
Canis lupus familiaris
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs
all
Try the new Gene page
Try the new Transcripts and proteins table
See TTC4 in Genome Data Viewer
Location:
chromosome: 5
Exon count:
10
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) 5 NC_051809.1 (54594550..54619793, complement)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 5 NC_006587.4 (54475489..54500962, complement)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 5 NC_049226.1 (54870103..54895370, complement)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) 5 NC_049265.1 (54590989..54616219, complement)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 5 NC_049746.1 (54481088..54506291, complement)

Chromosome 5 - NC_051809.1Genomic Context describing neighboring genes Neighboring gene tetratricopeptide repeat domain 22 Neighboring gene prolyl-tRNA synthetase 2, mitochondrial Neighboring gene uncharacterized LOC119871883 Neighboring gene maestro heat like repeat family member 7 Neighboring gene family with sequence similarity 151 member A Neighboring gene acyl-CoA thioesterase 11

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article

GeneRIFs: Gene References Into Functions

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables Hsp90 protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Preferred Names
tetratricopeptide repeat protein 4

NEW Try the new Transcript table

RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051809.1 Reference ROS_Cfam_1.0

    Range
    54594550..54619793 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038666150.1 → XP_038522078.1  tetratricopeptide repeat protein 4 isoform X1

    Conserved Domains (4) summary
    sd00006
    Location:96 → 126
    TPR; TPR repeat [structural motif]
    pfam06810
    Location:130 → 209
    Phage_GP20; Phage minor structural protein GP20
    pfam14559
    Location:76 → 139
    TPR_19; Tetratricopeptide repeat
    pfam18972
    Location:216 → 300
    Wheel; Cns1/TTC4 Wheel domain

  2. XM_038666149.1 → XP_038522077.1  tetratricopeptide repeat protein 4 isoform X2

    UniProtKB/TrEMBL
    A0A8C0KI65, A0A8I3NQF0, A0A8I3NU85
    Related
    ENSCAFP00845020259.1, ENSCAFT00845025709.1
    Conserved Domains (3) summary
    TIGR00990
    Location:40 → 171
    3a0801s09; mitochondrial precursor proteins import receptor (72 kDa mitochondrial outermembrane protein) (mitochondrial import receptor for the ADP/ATP carrier) (translocase of outermembrane tom70)
    sd00006
    Location:79 → 107
    TPR; TPR repeat [structural motif]
    pfam18972
    Location:270 → 354
    Wheel; Cns1/TTC4 Wheel domain

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049265.1 Alternate UMICH_Zoey_3.1

    Range
    54590989..54616219 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038476271.1 → XP_038332199.1  

    Conserved Domains (3) summary
    TIGR00990
    Location:40 → 171
    3a0801s09; mitochondrial precursor proteins import receptor (72 kDa mitochondrial outermembrane protein) (mitochondrial import receptor for the ADP/ATP carrier) (translocase of outermembrane tom70)
    sd00006
    Location:79 → 107
    TPR; TPR repeat [structural motif]
    pfam18972
    Location:270 → 354
    Wheel; Cns1/TTC4 Wheel domain

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049746.1 Alternate UNSW_CanFamBas_1.0

    Range
    54481088..54506291 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038601583.1 → XP_038457511.1  

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049226.1 Alternate UU_Cfam_GSD_1.0

    Range
    54870103..54895370 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038537439.1 → XP_038393367.1  tetratricopeptide repeat protein 4 isoform X1

    Conserved Domains (4) summary
    sd00006
    Location:96 → 126
    TPR; TPR repeat [structural motif]
    pfam06810
    Location:130 → 209
    Phage_GP20; Phage minor structural protein GP20
    pfam14559
    Location:76 → 139
    TPR_19; Tetratricopeptide repeat
    pfam18972
    Location:216 → 300
    Wheel; Cns1/TTC4 Wheel domain

  2. XM_038537438.1 → XP_038393366.1  tetratricopeptide repeat protein 4 isoform X2

    UniProtKB/TrEMBL
    A0A8C0KI65, A0A8I3NQF0, A0A8I3NU85
    Conserved Domains (3) summary
    TIGR00990
    Location:40 → 171
    3a0801s09; mitochondrial precursor proteins import receptor (72 kDa mitochondrial outermembrane protein) (mitochondrial import receptor for the ADP/ATP carrier) (translocase of outermembrane tom70)
    sd00006
    Location:79 → 107
    TPR; TPR repeat [structural motif]
    pfam18972
    Location:270 → 354
    Wheel; Cns1/TTC4 Wheel domain

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006587.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    54475489..54500962 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_848083.6 → XP_853176.2  tetratricopeptide repeat protein 4 isoform X2

    UniProtKB/TrEMBL
    A0A8C0KI65, A0A8I3NQF0, A0A8I3NU85
    Conserved Domains (3) summary
    TIGR00990
    Location:40 → 171
    3a0801s09; mitochondrial precursor proteins import receptor (72 kDa mitochondrial outermembrane protein) (mitochondrial import receptor for the ADP/ATP carrier) (translocase of outermembrane tom70)
    sd00006
    Location:79 → 107
    TPR; TPR repeat [structural motif]
    pfam18972
    Location:270 → 354
    Wheel; Cns1/TTC4 Wheel domain
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Molecular Biology Databases
Research Materials