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CYP27A1 cytochrome P450 family 27 subfamily A member 1 [ Canis lupus familiaris (dog) ]

Gene ID: 610489, updated on 25-Jul-2026
Official Symbol
CYP27A1provided by VGNC
Official Full Name
cytochrome P450 family 27 subfamily A member 1provided by VGNC
Primary source
VGNC:VGNC:50342
See related
Ensembl:ENSCAFG00845028313 RGD:12230964
Gene type
protein coding
RefSeq status
MODEL
Organism
Canis lupus familiaris
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs
all
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See CYP27A1 in Genome Data Viewer
Location:
chromosome: 37
Exon count:
10
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) 37 NC_051841.1 (25381673..25417125)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 37 NC_006619.4 (26186269..26221708)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 37 NC_049258.1 (25241871..25277345)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) 37 NC_049297.1 (25286426..25321814)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 37 NC_049778.1 (25221115..25256548)

Chromosome 37 - NC_051841.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC119867962 Neighboring gene tubulin tyrosine ligase like 4 Neighboring gene uncharacterized LOC111094371 Neighboring gene protein kinase AMP-activated non-catalytic subunit gamma 3 Neighboring gene uncharacterized LOC111094359 Neighboring gene Wnt family member 6

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables heme binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables iron ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables monooxygenase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in C21-steroid hormone biosynthetic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in cellular response to peptide hormone stimulus IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in cholesterol metabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in cortisol metabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in glucocorticoid biosynthetic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in mitochondrial inner membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 
Preferred Names
sterol 26-hydroxylase, mitochondrial
Names
cytochrome P450, family 27, subfamily A, polypeptide 1
XP_038303901.1
XP_038303902.1
XP_038319771.1
XP_038377876.1
XP_038377877.1
XP_038441836.1
XP_038506073.1
XP_038506074.1
XP_853094.4

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RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051841.1 Reference ROS_Cfam_1.0

    Range
    25381673..25417125
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038447973.1 → XP_038303901.1  sterol 26-hydroxylase, mitochondrial isoform X1

    UniProtKB/TrEMBL
    A0A8I3PW50
    Related
    ENSCAFP00845039275.1, ENSCAFT00845050090.1
    Conserved Domains (1) summary
    cl41757
    Location:92 → 528
    cytochrome_P450; cytochrome P450 (CYP) superfamily

  2. XM_038447974.1 → XP_038303902.1  sterol 26-hydroxylase, mitochondrial isoform X2

    UniProtKB/TrEMBL
    A0A8C0LTJ4
    Conserved Domains (1) summary
    cl41757
    Location:6 → 442
    cytochrome_P450; cytochrome P450 (CYP) superfamily

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049297.1 Alternate UMICH_Zoey_3.1

    Range
    25286426..25321814
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038521948.1 → XP_038377876.1  

    Conserved Domains (1) summary
    cl41757
    Location:92 → 528
    cytochrome_P450; cytochrome P450 (CYP) superfamily

  2. XM_038521949.1 → XP_038377877.1  

    Conserved Domains (1) summary
    cl41757
    Location:6 → 442
    cytochrome_P450; cytochrome P450 (CYP) superfamily

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049778.1 Alternate UNSW_CanFamBas_1.0

    Range
    25221115..25256548
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038650145.1 → XP_038506073.1  

    Conserved Domains (1) summary
    cl41757
    Location:92 → 528
    cytochrome_P450; cytochrome P450 (CYP) superfamily

  2. XM_038650146.1 → XP_038506074.1  

    Conserved Domains (1) summary
    cl41757
    Location:6 → 442
    cytochrome_P450; cytochrome P450 (CYP) superfamily

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049258.1 Alternate UU_Cfam_GSD_1.0

    Range
    25241871..25277345
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038585908.1 → XP_038441836.1  sterol 26-hydroxylase, mitochondrial isoform X3

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006619.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    26186269..26221708
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_848001.5 → XP_853094.4  sterol 26-hydroxylase, mitochondrial isoform X1

    UniProtKB/TrEMBL
    A0A8I3PW50
    Conserved Domains (1) summary
    cl41757
    Location:92 → 528
    cytochrome_P450; cytochrome P450 (CYP) superfamily

  2. XM_038463843.1 → XP_038319771.1  sterol 26-hydroxylase, mitochondrial isoform X2

    UniProtKB/TrEMBL
    A0A8C0LTJ4
    Conserved Domains (1) summary
    cl41757
    Location:6 → 442
    cytochrome_P450; cytochrome P450 (CYP) superfamily
Nucleotide Protein
Heading Accession and Version

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