U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

NDUFS8 NADH:ubiquinone oxidoreductase core subunit S8 [ Canis lupus familiaris (dog) ]

Gene ID: 610413, updated on 25-Jul-2026
Official Symbol
NDUFS8provided by VGNC
Official Full Name
NADH:ubiquinone oxidoreductase core subunit S8provided by VGNC
Primary source
VGNC:VGNC:51883
See related
Ensembl:ENSCAFG00845008677 RGD:12360095
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Canis lupus familiaris
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs
all
Try the new Gene page
Try the new Transcripts and proteins table
See NDUFS8 in Genome Data Viewer
Location:
chromosome: 18
Exon count:
9
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) 18 NC_051822.1 (50717789..50722042, complement)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 18 NC_006600.4 (48405896..48410143, complement)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 18 NC_049239.1 (50299726..50303986, complement)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) 18 NC_049278.1 (49931355..49935599, complement)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 18 NC_049759.1 (49506173..49510431, complement)

Chromosome 18 - NC_051822.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC111090990 Neighboring gene choline kinase alpha Neighboring gene T cell immune regulator 1, ATPase H+ transporting V0 subunit a3 Neighboring gene aldehyde dehydrogenase 3 family member B1 Neighboring gene unc-93 homolog B1, TLR signaling regulator

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables 4 iron, 4 sulfur cluster binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables NADH dehydrogenase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in mitochondrial electron transport, NADH to ubiquinone IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in mitochondrial respiratory chain complex I assembly IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 
Preferred Names
NADH dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrial
Names
NADH dehydrogenase (ubiquinone) Fe-S protein 8, 23kDa (NADH-coenzyme Q reductase)
NP_001239224.1
XP_038279405.1
XP_038279406.1
XP_038279407.1
XP_038279408.1

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001252295.1 → NP_001239224.1  NADH dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrial

    See identical proteins and their annotated locations for NP_001239224.1

    Status: VALIDATED

    Source sequence(s)
    CO682700, DN411417
    UniProtKB/TrEMBL
    A0A8C0QTP0
    Conserved Domains (1) summary
    PRK05888
    Location:54 → 210
    PRK05888; NADH-quinone oxidoreductase subunit NuoI

RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051822.1 Reference ROS_Cfam_1.0

    Range
    50717789..50722042 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038423480.1 → XP_038279408.1  NADH dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrial isoform X3

    UniProtKB/TrEMBL
    A0A8C0QTP0
    Conserved Domains (1) summary
    PRK05888
    Location:14 → 170
    PRK05888; NADH-quinone oxidoreductase subunit NuoI

  2. XM_038423478.1 → XP_038279406.1  NADH dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrial isoform X2

    UniProtKB/TrEMBL
    A0A8C0QTP0
    Conserved Domains (1) summary
    PRK05888
    Location:54 → 210
    PRK05888; NADH-quinone oxidoreductase subunit NuoI

  3. XM_038423477.1 → XP_038279405.1  NADH dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrial isoform X1

    UniProtKB/TrEMBL
    A0A8C0QTP0, A0A8I3N8W7
    Related
    ENSCAFP00845011858.1, ENSCAFT00845015271.1
    Conserved Domains (1) summary
    PRK05888
    Location:55 → 211
    PRK05888; NADH-quinone oxidoreductase subunit NuoI

  4. XM_038423479.1 → XP_038279407.1  NADH dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrial isoform X2

    UniProtKB/TrEMBL
    A0A8C0QTP0
    Conserved Domains (1) summary
    PRK05888
    Location:54 → 210
    PRK05888; NADH-quinone oxidoreductase subunit NuoI

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049278.1 Alternate UMICH_Zoey_3.1

    Range
    49931355..49935599 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049759.1 Alternate UNSW_CanFamBas_1.0

    Range
    49506173..49510431 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049239.1 Alternate UU_Cfam_GSD_1.0

    Range
    50299726..50303986 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006600.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    48405896..48410143 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Molecular Biology Databases
Research Materials
Miscellaneous