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PIK3R2 phosphoinositide-3-kinase regulatory subunit 2 [ Canis lupus familiaris (dog) ]

Gene ID: 609956, updated on 18-Sep-2020

Summary

Official Symbol
PIK3R2provided by VGNC
Official Full Name
phosphoinositide-3-kinase regulatory subunit 2provided by VGNC
Primary source
VGNC:VGNC:81919
See related
Ensembl:ENSCAFG00000014978
Gene type
protein coding
RefSeq status
MODEL
Organism
Canis lupus familiaris (sub-species: familiaris)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs

Genomic context

See PIK3R2 in Genome Data Viewer
Location:
chromosome: 20
Exon count:
16
Annotation release Status Assembly Chr Location
105 current CanFam3.1 (GCF_000002285.3) 20 NC_006602.3 (44826037..44838449, complement)

Chromosome 20 - NC_006602.3Genomic Context describing neighboring genes Neighboring gene RAB3A, member RAS oncogene family Neighboring gene MPV17 mitochondrial inner membrane protein like 2 Neighboring gene IFI30 lysosomal thiol reductase Neighboring gene microtubule associated serine/threonine kinase 3 Neighboring gene interleukin 12 receptor subunit beta 1

Genomic regions, transcripts, and products

Genomic Sequence:
NC_006602.3 Chromosome 20 Reference CanFam3.1 Primary Assembly

Pathways from PubChem

General gene information

Markers

Homology

General protein information

Preferred Names
phosphatidylinositol 3-kinase regulatory subunit beta
Names
phosphoinositide-3-kinase, regulatory subunit 2 (p85 beta)

NCBI Reference Sequences (RefSeq)

RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 105 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference CanFam3.1 Primary Assembly

Genomic

  1. NC_006602.3 Reference CanFam3.1 Primary Assembly

    Range
    44826037..44838449 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_847313.5XP_852406.2  phosphatidylinositol 3-kinase regulatory subunit beta

    UniProtKB/TrEMBL
    E2RH85
    Related
    ENSCAFP00000022072.4, ENSCAFT00000023779.5
    Conserved Domains (5) summary
    cd09930
    Location:613715
    SH2_cSH2_p85_like; C-terminal Src homology 2 (cSH2) domain found in p85
    cd09942
    Location:320430
    SH2_nSH2_p85_like; N-terminal Src homology 2 (nSH2) domain found in p85
    cd11909
    Location:780
    SH3_PI3K_p85beta; Src Homology 3 domain of the p85beta regulatory subunit of Class IA Phosphatidylinositol 3-kinases
    cd12926
    Location:435595
    iSH2_PIK3R2; Inter-Src homology 2 (iSH2) helical domain of Class IA Phosphoinositide 3-kinase Regulatory subunit 2, PIK3R2, also called p85beta
    cl02570
    Location:110294
    RhoGAP; RhoGAP: GTPase-activator protein (GAP) for Rho-like GTPases; GAPs towards Rho/Rac/Cdc42-like small GTPases. Small GTPases (G proteins) cluster into distinct families, and all act as molecular switches, active in their GTP-bound form but inactive when ...
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