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THEM4 thioesterase superfamily member 4 [ Canis lupus familiaris (dog) ]

Gene ID: 609163, updated on 27-Jun-2026
Official Symbol
THEM4provided by VGNC
Official Full Name
thioesterase superfamily member 4provided by VGNC
Primary source
VGNC:VGNC:47341
See related
Ensembl:ENSCAFG00845025388 RGD:12123657
Gene type
protein coding
RefSeq status
MODEL
Organism
Canis lupus familiaris (sub-species: familiaris)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs
all
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See THEM4 in Genome Data Viewer
Location:
chromosome: 17
Exon count:
6
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) 17 NC_051821.1 (61902842..61944538, complement)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 17 NC_006599.4 (60337687..60369117, complement)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 17 NC_049238.1 (61554930..61586689, complement)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) 17 NC_049277.1 (60735719..60771111, complement)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 17 NC_049758.1 (60826006..60857205, complement)

Chromosome 17 - NC_051821.1Genomic Context describing neighboring genes Neighboring gene C2 calcium dependent domain containing 4D Neighboring gene thioesterase superfamily member 5 Neighboring gene uncharacterized LOC111090730 Neighboring gene S100 calcium binding protein A10 Neighboring gene S100 calcium binding protein A11

Go to nucleotide: Graphics FASTA GenBank

GeneRIFs: Gene References Into Functions

Homology

Preferred Names
acyl-coenzyme A thioesterase THEM4
XP_022260721.1
XP_038279149.1
XP_038355634.1
XP_038355635.1
XP_038355636.1
XP_038418207.1
XP_038482300.1

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RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051821.1 Reference ROS_Cfam_1.0

    Range
    61902842..61944538 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038423221.1 → XP_038279149.1  acyl-coenzyme A thioesterase THEM4 isoform X1

    UniProtKB/TrEMBL
    A0A8C0K6I6, A0A8I3PUC0
    Related
    ENSCAFP00845035106.1, ENSCAFT00845044799.1
    Conserved Domains (1) summary
    cd03443
    Location:116 → 212
    PaaI_thioesterase; PaaI_thioesterase is a tetrameric acyl-CoA thioesterase with a hot dog fold and one of several proteins responsible for phenylacetic acid (PA) degradation in bacteria. Although orthologs of PaaI exist in archaea and eukaryotes, their function has not ...

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049277.1 Alternate UMICH_Zoey_3.1

    Range
    60735719..60771111 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038499706.1 → XP_038355634.1  

  2. XM_038499708.1 → XP_038355636.1  

  3. XM_038499707.1 → XP_038355635.1  

RNA

  1. XR_005338978.1 RNA Sequence

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049758.1 Alternate UNSW_CanFamBas_1.0

    Range
    60826006..60857205 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038626372.1 → XP_038482300.1  

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049238.1 Alternate UU_Cfam_GSD_1.0

    Range
    61554930..61586689 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038562279.1 → XP_038418207.1  acyl-coenzyme A thioesterase THEM4 isoform X6

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006599.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    60337687..60369117 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_022405013.2 → XP_022260721.1  acyl-coenzyme A thioesterase THEM4 isoform X7

    Conserved Domains (1) summary
    cd03443
    Location:116 → 174
    PaaI_thioesterase; PaaI_thioesterase is a tetrameric acyl-CoA thioesterase with a hot dog fold and one of several proteins responsible for phenylacetic acid (PA) degradation in bacteria. Although orthologs of PaaI exist in archaea and eukaryotes, their function has not ...
Nucleotide Protein
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