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DIXDC1 DIX domain containing 1 [ Canis lupus familiaris (dog) ]

Gene ID: 608957, updated on 25-Jul-2026
Official Symbol
DIXDC1provided by VGNC
Official Full Name
DIX domain containing 1provided by VGNC
Primary source
VGNC:VGNC:39969
See related
Ensembl:ENSCAFG00845001790 RGD:12183563
Gene type
protein coding
RefSeq status
MODEL
Organism
Canis lupus familiaris
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs
all
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Try the new Transcripts and proteins table
See DIXDC1 in Genome Data Viewer
Location:
chromosome: 5
Exon count:
24
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) 5 NC_051809.1 (21119943..21191396, complement)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 5 NC_006587.4 (21019330..21090701, complement)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 5 NC_049226.1 (21130502..21201971, complement)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) 5 NC_049265.1 (21181292..21252715, complement)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 5 NC_049746.1 (21081791..21153169, complement)

Chromosome 5 - NC_051809.1Genomic Context describing neighboring genes Neighboring gene PIH1 domain containing 2 Neighboring gene dihydrolipoamide S-acetyltransferase Neighboring gene uncharacterized LOC106558799 Neighboring gene chromosome 5 C11orf52 homolog Neighboring gene ATP synthase subunit ATP5MPL, mitochondrial-like Neighboring gene heat shock protein family B (small) member 2

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in canonical Wnt signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytosol IEA
Inferred from Electronic Annotation
more info
 PubMed 
Preferred Names
dixin

NEW Try the new Transcript table

RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051809.1 Reference ROS_Cfam_1.0

    Range
    21119943..21191396 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038664899.1 → XP_038520827.1  dixin isoform X5

    UniProtKB/TrEMBL
    A0A8I3MK00
    Related
    ENSCAFP00845002506.1, ENSCAFT00845003146.1
    Conserved Domains (3) summary
    COG1196
    Location:280 → 464
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    pfam00778
    Location:599 → 676
    DIX; DIX domain
    cd21213
    Location:21 → 127
    CH_DIXDC1; calponin homology (CH) domain found in Dixin and similar proteins

  2. XM_038664896.1 → XP_038520824.1  dixin isoform X2

    UniProtKB/TrEMBL
    A0A8I3MK00
    Conserved Domains (3) summary
    COG1196
    Location:295 → 486
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    pfam00778
    Location:621 → 698
    DIX; DIX domain
    cd21213
    Location:43 → 149
    CH_DIXDC1; calponin homology (CH) domain found in Dixin and similar proteins

  3. XM_038664901.1 → XP_038520829.1  dixin isoform X7

    UniProtKB/TrEMBL
    A0A8I3MK00
    Conserved Domains (2) summary
    COG1196
    Location:303 → 487
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    cd21213
    Location:44 → 150
    CH_DIXDC1; calponin homology (CH) domain found in Dixin and similar proteins

  4. XM_038664897.1 → XP_038520825.1  dixin isoform X3

    UniProtKB/TrEMBL
    A0A8I3MK00
    Conserved Domains (3) summary
    COG1196
    Location:302 → 486
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    pfam00778
    Location:621 → 698
    DIX; DIX domain
    cd21213
    Location:44 → 149
    CH_DIXDC1; calponin homology (CH) domain found in Dixin and similar proteins

  5. XM_038664895.1 → XP_038520823.1  dixin isoform X1

    UniProtKB/TrEMBL
    A0A8I3MK00
    Conserved Domains (3) summary
    COG1196
    Location:303 → 487
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    pfam00778
    Location:622 → 699
    DIX; DIX domain
    cd21213
    Location:44 → 150
    CH_DIXDC1; calponin homology (CH) domain found in Dixin and similar proteins

  6. XM_038664900.1 → XP_038520828.1  dixin isoform X6

    UniProtKB/TrEMBL
    A0A8I3MK00
    Conserved Domains (3) summary
    COG1196
    Location:260 → 451
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    pfam00778
    Location:586 → 663
    DIX; DIX domain
    cd21213
    Location:44 → 150
    CH_DIXDC1; calponin homology (CH) domain found in Dixin and similar proteins

  7. XM_038664898.1 → XP_038520826.1  dixin isoform X4

    UniProtKB/TrEMBL
    A0A8I3MEG7, A0A8I3MK00
    Related
    ENSCAFP00845002524.1, ENSCAFT00845003169.1
    Conserved Domains (3) summary
    COG1196
    Location:281 → 465
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    pfam00778
    Location:600 → 677
    DIX; DIX domain
    cd21213
    Location:22 → 128
    CH_DIXDC1; calponin homology (CH) domain found in Dixin and similar proteins

  8. XM_038664902.1 → XP_038520830.1  dixin isoform X8

    UniProtKB/TrEMBL
    A0A8I3MIV3
    Related
    ENSCAFP00845002515.1, ENSCAFT00845003157.1
    Conserved Domains (2) summary
    COG1196
    Location:70 → 254
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    pfam00778
    Location:389 → 466
    DIX; DIX domain

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049265.1 Alternate UMICH_Zoey_3.1

    Range
    21181292..21252715 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038475039.1 → XP_038330967.1  

    Conserved Domains (3) summary
    COG1196
    Location:280 → 464
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    pfam00778
    Location:599 → 676
    DIX; DIX domain
    cd21213
    Location:21 → 127
    CH_DIXDC1; calponin homology (CH) domain found in Dixin and similar proteins

  2. XM_038475036.1 → XP_038330964.1  

    Conserved Domains (3) summary
    COG1196
    Location:295 → 486
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    pfam00778
    Location:621 → 698
    DIX; DIX domain
    cd21213
    Location:43 → 149
    CH_DIXDC1; calponin homology (CH) domain found in Dixin and similar proteins

  3. XM_038475041.1 → XP_038330969.1  

    Conserved Domains (2) summary
    COG1196
    Location:303 → 487
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    cd21213
    Location:44 → 150
    CH_DIXDC1; calponin homology (CH) domain found in Dixin and similar proteins

  4. XM_038475037.1 → XP_038330965.1  

    Conserved Domains (3) summary
    COG1196
    Location:302 → 486
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    pfam00778
    Location:621 → 698
    DIX; DIX domain
    cd21213
    Location:44 → 149
    CH_DIXDC1; calponin homology (CH) domain found in Dixin and similar proteins

  5. XM_038475035.1 → XP_038330963.1  

    Conserved Domains (3) summary
    COG1196
    Location:303 → 487
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    pfam00778
    Location:622 → 699
    DIX; DIX domain
    cd21213
    Location:44 → 150
    CH_DIXDC1; calponin homology (CH) domain found in Dixin and similar proteins

  6. XM_038475040.1 → XP_038330968.1  

    Conserved Domains (3) summary
    COG1196
    Location:260 → 451
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    pfam00778
    Location:586 → 663
    DIX; DIX domain
    cd21213
    Location:44 → 150
    CH_DIXDC1; calponin homology (CH) domain found in Dixin and similar proteins

  7. XM_038475038.1 → XP_038330966.1  

    Conserved Domains (3) summary
    COG1196
    Location:281 → 465
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    pfam00778
    Location:600 → 677
    DIX; DIX domain
    cd21213
    Location:22 → 128
    CH_DIXDC1; calponin homology (CH) domain found in Dixin and similar proteins

  8. XM_038475042.1 → XP_038330970.1  

    Conserved Domains (2) summary
    COG1196
    Location:70 → 254
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    pfam00778
    Location:389 → 466
    DIX; DIX domain

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049746.1 Alternate UNSW_CanFamBas_1.0

    Range
    21081791..21153169 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038600368.1 → XP_038456296.1  

  2. XM_038600365.1 → XP_038456293.1  

  3. XM_038600370.1 → XP_038456298.1  

  4. XM_038600366.1 → XP_038456294.1  

  5. XM_038600364.1 → XP_038456292.1  

  6. XM_038600369.1 → XP_038456297.1  

  7. XM_038600367.1 → XP_038456295.1  

  8. XM_038600371.1 → XP_038456299.1  

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049226.1 Alternate UU_Cfam_GSD_1.0

    Range
    21130502..21201971 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038536175.1 → XP_038392103.1  dixin isoform X5

    UniProtKB/TrEMBL
    A0A8I3MK00
    Conserved Domains (3) summary
    COG1196
    Location:280 → 464
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    pfam00778
    Location:599 → 676
    DIX; DIX domain
    cd21213
    Location:21 → 127
    CH_DIXDC1; calponin homology (CH) domain found in Dixin and similar proteins

  2. XM_038536171.1 → XP_038392099.1  dixin isoform X2

    UniProtKB/TrEMBL
    A0A8I3MK00
    Conserved Domains (3) summary
    COG1196
    Location:295 → 486
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    pfam00778
    Location:621 → 698
    DIX; DIX domain
    cd21213
    Location:43 → 149
    CH_DIXDC1; calponin homology (CH) domain found in Dixin and similar proteins

  3. XM_038536177.1 → XP_038392105.1  dixin isoform X7

    UniProtKB/TrEMBL
    A0A8I3MK00
    Conserved Domains (2) summary
    COG1196
    Location:303 → 487
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    cd21213
    Location:44 → 150
    CH_DIXDC1; calponin homology (CH) domain found in Dixin and similar proteins

  4. XM_038536173.1 → XP_038392101.1  dixin isoform X3

    UniProtKB/TrEMBL
    A0A8I3MK00
    Conserved Domains (3) summary
    COG1196
    Location:302 → 486
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    pfam00778
    Location:621 → 698
    DIX; DIX domain
    cd21213
    Location:44 → 149
    CH_DIXDC1; calponin homology (CH) domain found in Dixin and similar proteins

  5. XM_038536170.1 → XP_038392098.1  dixin isoform X1

    UniProtKB/TrEMBL
    A0A8I3MK00
    Conserved Domains (3) summary
    COG1196
    Location:303 → 487
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    pfam00778
    Location:622 → 699
    DIX; DIX domain
    cd21213
    Location:44 → 150
    CH_DIXDC1; calponin homology (CH) domain found in Dixin and similar proteins

  6. XM_038536176.1 → XP_038392104.1  dixin isoform X6

    UniProtKB/TrEMBL
    A0A8I3MK00
    Conserved Domains (3) summary
    COG1196
    Location:260 → 451
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    pfam00778
    Location:586 → 663
    DIX; DIX domain
    cd21213
    Location:44 → 150
    CH_DIXDC1; calponin homology (CH) domain found in Dixin and similar proteins

  7. XM_038536174.1 → XP_038392102.1  dixin isoform X4

    UniProtKB/TrEMBL
    A0A8I3MEG7, A0A8I3MK00
    Conserved Domains (3) summary
    COG1196
    Location:281 → 465
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    pfam00778
    Location:600 → 677
    DIX; DIX domain
    cd21213
    Location:22 → 128
    CH_DIXDC1; calponin homology (CH) domain found in Dixin and similar proteins

  8. XM_038536178.1 → XP_038392106.1  dixin isoform X8

    UniProtKB/TrEMBL
    A0A8I3MIV3
    Conserved Domains (2) summary
    COG1196
    Location:70 → 254
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    pfam00778
    Location:389 → 466
    DIX; DIX domain

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006587.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    21019330..21090701 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_014113421.3 → XP_013968896.1  dixin isoform X5

    UniProtKB/TrEMBL
    A0A8I3MK00
    Conserved Domains (3) summary
    COG1196
    Location:280 → 464
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    pfam00778
    Location:599 → 676
    DIX; DIX domain
    cd21213
    Location:21 → 127
    CH_DIXDC1; calponin homology (CH) domain found in Dixin and similar proteins

  2. XM_014113419.3 → XP_013968894.1  dixin isoform X2

    UniProtKB/TrEMBL
    A0A8I3MK00
    Conserved Domains (3) summary
    COG1196
    Location:295 → 486
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    pfam00778
    Location:621 → 698
    DIX; DIX domain
    cd21213
    Location:43 → 149
    CH_DIXDC1; calponin homology (CH) domain found in Dixin and similar proteins

  3. XM_005619777.4 → XP_005619834.1  dixin isoform X7

    UniProtKB/TrEMBL
    A0A8I3MK00
    Conserved Domains (2) summary
    COG1196
    Location:303 → 487
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    cd21213
    Location:44 → 150
    CH_DIXDC1; calponin homology (CH) domain found in Dixin and similar proteins

  4. XM_014113420.3 → XP_013968895.1  dixin isoform X3

    UniProtKB/TrEMBL
    A0A8I3MK00
    Conserved Domains (3) summary
    COG1196
    Location:302 → 486
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    pfam00778
    Location:621 → 698
    DIX; DIX domain
    cd21213
    Location:44 → 149
    CH_DIXDC1; calponin homology (CH) domain found in Dixin and similar proteins

  5. XM_005619776.4 → XP_005619833.1  dixin isoform X1

    UniProtKB/TrEMBL
    A0A8I3MK00
    Conserved Domains (3) summary
    COG1196
    Location:303 → 487
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    pfam00778
    Location:622 → 699
    DIX; DIX domain
    cd21213
    Location:44 → 150
    CH_DIXDC1; calponin homology (CH) domain found in Dixin and similar proteins

  6. XM_038510675.1 → XP_038366603.1  dixin isoform X6

    UniProtKB/TrEMBL
    A0A8I3MK00
    Conserved Domains (3) summary
    COG1196
    Location:260 → 451
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    pfam00778
    Location:586 → 663
    DIX; DIX domain
    cd21213
    Location:44 → 150
    CH_DIXDC1; calponin homology (CH) domain found in Dixin and similar proteins

  7. XM_856985.6 → XP_862078.1  dixin isoform X4

    UniProtKB/TrEMBL
    A0A8I3MEG7, A0A8I3MK00
    Conserved Domains (3) summary
    COG1196
    Location:281 → 465
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    pfam00778
    Location:600 → 677
    DIX; DIX domain
    cd21213
    Location:22 → 128
    CH_DIXDC1; calponin homology (CH) domain found in Dixin and similar proteins

  8. XM_857012.6 → XP_862105.2  dixin isoform X8

    UniProtKB/TrEMBL
    A0A8I3MIV3
    Conserved Domains (2) summary
    COG1196
    Location:70 → 254
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    pfam00778
    Location:389 → 466
    DIX; DIX domain
Nucleotide Protein
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