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FGF5 fibroblast growth factor 5 [ Canis lupus familiaris (dog) ]

Gene ID: 608459, updated on 8-Apr-2026
Official Symbol
FGF5provided by VGNC
Official Full Name
fibroblast growth factor 5provided by VGNC
Primary source
VGNC:VGNC:40851
See related
Ensembl:ENSCAFG00845017837 RGD:12317503
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Canis lupus familiaris (sub-species: familiaris)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs
all
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See FGF5 in Genome Data Viewer
Location:
chromosome: 32
Exon count:
3
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) 32 NC_051836.1 (4533042..4556071)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 32 NC_006614.4 (37352539..37372398, complement)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 32 NC_049253.1 (35474935..35494799, complement)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) 32 NC_049292.1 (4572084..4591201)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 32 NC_049773.1 (4469686..4489573)

Chromosome 32 - NC_051836.1Genomic Context describing neighboring genes Neighboring gene small nuclear ribonucleoprotein F Neighboring gene uncharacterized LOC119867172 Neighboring gene PR/SET domain 8 Neighboring gene uncharacterized LOC111093662 Neighboring gene cilia and flagella associated protein 299 Neighboring gene uncharacterized LOC111093683

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. The long and the short of it: evidence that FGF5 is a major determinant of canine 'hair'-itability. Housley DJ, et al. Anim Genet, 2006 Aug. PMID 16879338
  2. Coat variation in the domestic dog is governed by variants in three genes. Cadieu E, et al. Science, 2009 Oct 2. PMID 19713490, Free PMC Article
  3. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  4. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables fibroblast growth factor receptor binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables growth factor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in animal organ morphogenesis IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in cell differentiation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in fibroblast growth factor receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of cell population proliferation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of gene expression IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of protein phosphorylation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of cell migration IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 
Preferred Names
fibroblast growth factor 5
Names
FGF-5
NP_001041594.1

Length

  • 270

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001048129.1 → NP_001041594.1  fibroblast growth factor 5 precursor

    See identical proteins and their annotated locations for NP_001041594.1

    Status: PROVISIONAL

    Source sequence(s)
    DQ268832
    UniProtKB/TrEMBL
    A0A8C0TEW3
    Related
    ENSCAFP00845024720.1, ENSCAFT00845031580.1
    Conserved Domains (1) summary
    smart00442
    Location:87 → 220
    FGF; Acidic and basic fibroblast growth factor family

RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051836.1 Reference ROS_Cfam_1.0

    Range
    4533042..4556071
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038443794.1 → XP_038299722.1  fibroblast growth factor 5 isoform X1

    UniProtKB/TrEMBL
    A0A8C0TEY3, A0A8I3NTW2
    Related
    ENSCAFP00845024770.1, ENSCAFT00845031645.1
    Conserved Domains (1) summary
    cl00060
    Location:91 → 120
    FGF; Acidic and basic fibroblast growth factor family; FGFs are mitogens, which stimulate growth or differentiation of cells of mesodermal or neuroectodermal origin. The family plays essential roles in patterning and differentiation during vertebrate ...

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049292.1 Alternate UMICH_Zoey_3.1

    Range
    4572084..4591201
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049773.1 Alternate UNSW_CanFamBas_1.0

    Range
    4469686..4489573
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049253.1 Alternate UU_Cfam_GSD_1.0

    Range
    35474935..35494799 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006614.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    37352539..37372398 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q20FD0.2 GenPept UniProtKB/Swiss-Prot:Q20FD0

Gene LinkOut

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Molecular Biology Databases
Research Materials