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IGFBP4 insulin like growth factor binding protein 4 [ Canis lupus familiaris (dog) ]

Gene ID: 608158, updated on 27-Jun-2026
Official Symbol
IGFBP4provided by VGNC
Official Full Name
insulin like growth factor binding protein 4provided by VGNC
Primary source
VGNC:VGNC:41905
See related
Ensembl:ENSCAFG00845008138 RGD:12316258
Gene type
protein coding
RefSeq status
MODEL
Organism
Canis lupus familiaris (sub-species: familiaris)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs
all
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See IGFBP4 in Genome Data Viewer
Location:
chromosome: 9
Exon count:
4
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) 9 NC_051813.1 (22962295..22974991, complement)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 9 NC_006591.4 (21642296..21654538, complement)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 9 NC_049230.1 (22120045..22132291, complement)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) 9 NC_049269.1 (21736648..21748885, complement)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 9 NC_049750.1 (21995532..22007775, complement)

Chromosome 9 - NC_051813.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC111097354 Neighboring gene tensin 4 Neighboring gene microRNA mir-8888 Neighboring gene uncharacterized LOC106559289 Neighboring gene uncharacterized LOC111097355 Neighboring gene TAF12 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 20kDa pseudogene Neighboring gene DNA topoisomerase II alpha

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables insulin-like growth factor I binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables insulin-like growth factor II binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in regulation of insulin-like growth factor receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in extracellular region IEA
Inferred from Electronic Annotation
more info
 PubMed 
Preferred Names
insulin-like growth factor-binding protein 4

NEW Try the new Transcript table

RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051813.1 Reference ROS_Cfam_1.0

    Range
    22962295..22974991 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038676557.1 → XP_038532485.1  insulin-like growth factor-binding protein 4

    UniProtKB/TrEMBL
    A0A8I3NA54
    Related
    ENSCAFP00845011095.1, ENSCAFT00845014323.1
    Conserved Domains (2) summary
    smart00121
    Location:25 → 101
    IB; Insulin growth factor-binding protein homologues
    pfam00086
    Location:174 → 249
    Thyroglobulin_1; Thyroglobulin type-1 repeat

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049269.1 Alternate UMICH_Zoey_3.1

    Range
    21736648..21748885 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038485614.1 → XP_038341542.1  

    Conserved Domains (2) summary
    smart00121
    Location:25 → 101
    IB; Insulin growth factor-binding protein homologues
    pfam00086
    Location:174 → 249
    Thyroglobulin_1; Thyroglobulin type-1 repeat

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049750.1 Alternate UNSW_CanFamBas_1.0

    Range
    21995532..22007775 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038611364.1 → XP_038467292.1  

    Conserved Domains (2) summary
    smart00121
    Location:25 → 101
    IB; Insulin growth factor-binding protein homologues
    pfam00086
    Location:174 → 249
    Thyroglobulin_1; Thyroglobulin type-1 repeat

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049230.1 Alternate UU_Cfam_GSD_1.0

    Range
    22120045..22132291 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038547380.1 → XP_038403308.1  insulin-like growth factor-binding protein 4

    UniProtKB/TrEMBL
    A0A8I3NA54
    Conserved Domains (2) summary
    smart00121
    Location:25 → 101
    IB; Insulin growth factor-binding protein homologues
    pfam00086
    Location:174 → 249
    Thyroglobulin_1; Thyroglobulin type-1 repeat

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006591.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    21642296..21654538 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_845091.5 → XP_850184.2  insulin-like growth factor-binding protein 4

    UniProtKB/TrEMBL
    A0A8I3NA54
    Conserved Domains (2) summary
    smart00121
    Location:25 → 101
    IB; Insulin growth factor-binding protein homologues
    pfam00086
    Location:174 → 249
    Thyroglobulin_1; Thyroglobulin type-1 repeat
Nucleotide Protein
Heading Accession and Version

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