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MSRA methionine sulfoxide reductase A [ Canis lupus familiaris (dog) ]

Gene ID: 608103, updated on 25-Jul-2026
Official Symbol
MSRAprovided by VGNC
Official Full Name
methionine sulfoxide reductase Aprovided by VGNC
Primary source
VGNC:VGNC:43449
See related
Ensembl:ENSCAFG00845020456 RGD:12393132
Gene type
protein coding
RefSeq status
MODEL
Organism
Canis lupus familiaris
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs
Try the new Gene page
Try the new Transcripts and proteins table
See MSRA in Genome Data Viewer
Location:
chromosome: 25
Exon count:
9
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) 25 NC_051829.1 (27767761..28194963, complement)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 25 NC_006607.4 (28256191..28688850, complement)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 25 NC_049246.1 (27771061..28204784, complement)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) 25 NC_049285.1 (27722315..28155074, complement)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 25 NC_049766.1 (27616218..28042765, complement)

Chromosome 25 - NC_051829.1Genomic Context describing neighboring genes Neighboring gene piggyBac transposable element-derived protein 2-like Neighboring gene decreased expression in renal and prostate cancer protein-like Neighboring gene thymosin beta-4-like Neighboring gene uncharacterized LOC111092374

Markers

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables peptide-methionine (S)-S-oxide reductase activity IEA
Inferred from Electronic Annotation
more info
PubMed 
Process Evidence Code Pubs
involved_in cellular response to oxidative stress IEA
Inferred from Electronic Annotation
more info
PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
PubMed 
Preferred Names
mitochondrial peptide methionine sulfoxide reductase
Names
mitochondrial peptide methionine sulfoxide reductase-like
XP_013963045.2
XP_013963046.2
XP_038291201.1
XP_038291202.1
XP_038291203.1
XP_038291204.1
XP_038291205.1
XP_038291207.1
XP_038291208.1
XP_038314498.1
XP_038314499.1
XP_038314500.1
XP_038314501.1
XP_038366148.1
XP_038366149.1
XP_038366150.1
XP_038366151.1
XP_038366152.1
XP_038366153.1
XP_038429605.1
XP_038429606.1
XP_038429607.1
XP_038429608.1
XP_038429609.1
XP_038429610.1
XP_038493909.1
XP_038493910.1
XP_038493911.1
XP_038493912.1
XP_038493913.1
XP_038493914.1
XP_038493915.1
XP_038493916.1

NEW Try the new Transcript table

RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051829.1 Reference ROS_Cfam_1.0

    Range
    27767761..28194963 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038435276.1XP_038291204.1  mitochondrial peptide methionine sulfoxide reductase isoform X4

    Conserved Domains (1) summary
    cl00366
    Location:26195
    PMSR; Peptide methionine sulfoxide reductase
  2. XM_038435277.1XP_038291205.1  mitochondrial peptide methionine sulfoxide reductase isoform X5

    Conserved Domains (1) summary
    cl00366
    Location:26144
    PMSR; Peptide methionine sulfoxide reductase
  3. XM_038435273.1XP_038291201.1  mitochondrial peptide methionine sulfoxide reductase isoform X1

    UniProtKB/TrEMBL
    A0A8I3P7W6, A0A8I3S4F3
    Related
    ENSCAFP00845028248.1, ENSCAFT00845036094.1
    Conserved Domains (1) summary
    PRK00058
    Location:26230
    PRK00058; peptide-methionine (S)-S-oxide reductase MsrA
  4. XM_038435274.1XP_038291202.1  mitochondrial peptide methionine sulfoxide reductase isoform X2

    Conserved Domains (1) summary
    PRK00058
    Location:26207
    PRK00058; peptide-methionine (S)-S-oxide reductase MsrA
  5. XM_038435279.1XP_038291207.1  mitochondrial peptide methionine sulfoxide reductase isoform X6

    UniProtKB/TrEMBL
    A0A8I3PD07
    Related
    ENSCAFP00845028285.1, ENSCAFT00845036150.1
    Conserved Domains (1) summary
    PRK00058
    Location:1189
    PRK00058; peptide-methionine (S)-S-oxide reductase MsrA
  6. XM_038435280.1XP_038291208.1  mitochondrial peptide methionine sulfoxide reductase isoform X7

    UniProtKB/TrEMBL
    A0A8I3PK74
    Related
    ENSCAFP00845028337.1, ENSCAFT00845036215.1
    Conserved Domains (1) summary
    cl00366
    Location:2166
    PMSR; Peptide methionine sulfoxide reductase
  7. XM_038435275.1XP_038291203.1  mitochondrial peptide methionine sulfoxide reductase isoform X3

    Conserved Domains (1) summary
    PRK00058
    Location:4188
    PRK00058; peptide-methionine (S)-S-oxide reductase MsrA

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049285.1 Alternate UMICH_Zoey_3.1

    Range
    27722315..28155074 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038510222.1XP_038366150.1  

    Conserved Domains (1) summary
    cl00366
    Location:26195
    PMSR; Peptide methionine sulfoxide reductase
  2. XM_038510223.1XP_038366151.1  

    Conserved Domains (1) summary
    cl00366
    Location:26144
    PMSR; Peptide methionine sulfoxide reductase
  3. XM_038510220.1XP_038366148.1  

    Conserved Domains (1) summary
    PRK00058
    Location:26230
    PRK00058; peptide-methionine (S)-S-oxide reductase MsrA
  4. XM_038510221.1XP_038366149.1  

    Conserved Domains (1) summary
    PRK00058
    Location:26207
    PRK00058; peptide-methionine (S)-S-oxide reductase MsrA
  5. XM_038510224.1XP_038366152.1  

    Conserved Domains (1) summary
    PRK00058
    Location:1189
    PRK00058; peptide-methionine (S)-S-oxide reductase MsrA
  6. XM_038510225.1XP_038366153.1  

    Conserved Domains (1) summary
    cl00366
    Location:2166
    PMSR; Peptide methionine sulfoxide reductase

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049766.1 Alternate UNSW_CanFamBas_1.0

    Range
    27616218..28042765 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038637985.1XP_038493913.1  

    Conserved Domains (1) summary
    cl00366
    Location:26195
    PMSR; Peptide methionine sulfoxide reductase
  2. XM_038637986.1XP_038493914.1  

    Conserved Domains (1) summary
    cl00366
    Location:26144
    PMSR; Peptide methionine sulfoxide reductase
  3. XM_038637981.1XP_038493909.1  

  4. XM_038637982.1XP_038493910.1  

  5. XM_038637987.1XP_038493915.1  

    Conserved Domains (1) summary
    PRK00058
    Location:1189
    PRK00058; peptide-methionine (S)-S-oxide reductase MsrA
  6. XM_038637988.1XP_038493916.1  

    Conserved Domains (1) summary
    cl00366
    Location:2166
    PMSR; Peptide methionine sulfoxide reductase
  7. XM_038637983.1XP_038493911.1  

    Conserved Domains (1) summary
    PRK00058
    Location:4188
    PRK00058; peptide-methionine (S)-S-oxide reductase MsrA
  8. XM_038637984.1XP_038493912.1  

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049246.1 Alternate UU_Cfam_GSD_1.0

    Range
    27771061..28204784 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038573679.1XP_038429607.1  mitochondrial peptide methionine sulfoxide reductase isoform X4

    Conserved Domains (1) summary
    cl00366
    Location:26195
    PMSR; Peptide methionine sulfoxide reductase
  2. XM_038573680.1XP_038429608.1  mitochondrial peptide methionine sulfoxide reductase isoform X5

    Conserved Domains (1) summary
    cl00366
    Location:26144
    PMSR; Peptide methionine sulfoxide reductase
  3. XM_038573677.1XP_038429605.1  mitochondrial peptide methionine sulfoxide reductase isoform X1

    UniProtKB/TrEMBL
    A0A8C0KDT7, A0A8I3S4F3
  4. XM_038573678.1XP_038429606.1  mitochondrial peptide methionine sulfoxide reductase isoform X2

  5. XM_038573681.1XP_038429609.1  mitochondrial peptide methionine sulfoxide reductase isoform X6

    UniProtKB/TrEMBL
    A0A8I3PD07
    Conserved Domains (1) summary
    PRK00058
    Location:1189
    PRK00058; peptide-methionine (S)-S-oxide reductase MsrA
  6. XM_038573682.1XP_038429610.1  mitochondrial peptide methionine sulfoxide reductase isoform X7

    UniProtKB/TrEMBL
    A0A8I3PK74
    Conserved Domains (1) summary
    cl00366
    Location:2166
    PMSR; Peptide methionine sulfoxide reductase

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006607.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    28256191..28688850 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038458572.1XP_038314500.1  mitochondrial peptide methionine sulfoxide reductase isoform X4

    Conserved Domains (1) summary
    cl00366
    Location:26195
    PMSR; Peptide methionine sulfoxide reductase
  2. XM_038458573.1XP_038314501.1  mitochondrial peptide methionine sulfoxide reductase isoform X5

    Conserved Domains (1) summary
    cl00366
    Location:26144
    PMSR; Peptide methionine sulfoxide reductase
  3. XM_038458570.1XP_038314498.1  mitochondrial peptide methionine sulfoxide reductase isoform X1

    UniProtKB/TrEMBL
    A0A8I3S4F3
    Conserved Domains (1) summary
    PRK00058
    Location:26230
    PRK00058; peptide-methionine (S)-S-oxide reductase MsrA
  4. XM_038458571.1XP_038314499.1  mitochondrial peptide methionine sulfoxide reductase isoform X2

    Conserved Domains (1) summary
    PRK00058
    Location:26207
    PRK00058; peptide-methionine (S)-S-oxide reductase MsrA
  5. XM_014107570.3XP_013963045.2  mitochondrial peptide methionine sulfoxide reductase isoform X6

    Conserved Domains (1) summary
    PRK00058
    Location:1189
    PRK00058; peptide-methionine (S)-S-oxide reductase MsrA
  6. XM_014107571.3XP_013963046.2  mitochondrial peptide methionine sulfoxide reductase isoform X7

    Conserved Domains (1) summary
    cl00366
    Location:2166
    PMSR; Peptide methionine sulfoxide reductase