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SIM2 SIM bHLH transcription factor 2 [ Canis lupus familiaris (dog) ]

Gene ID: 607987, updated on 5-Mar-2024

Summary

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Official Symbol
SIM2provided by VGNC
Official Full Name
SIM bHLH transcription factor 2provided by VGNC
Primary source
VGNC:VGNC:46175
See related
Ensembl:ENSCAFG00845027660
Gene type
protein coding
RefSeq status
MODEL
Organism
Canis lupus familiaris (sub-species: familiaris)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 31
Exon count:
11
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) 31 NC_051835.1 (31182551..31236268)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 31 NC_006613.4 (30940849..30994549)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 31 NC_049252.1 (31553961..31607783)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) 31 NC_049291.1 (31050827..31104585)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 31 NC_049772.1 (31063591..31118290)

Chromosome 31 - NC_051835.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC111093492 Neighboring gene uncharacterized LOC119867060 Neighboring gene uncharacterized LOC111093561 Neighboring gene holocarboxylase synthetase Neighboring gene uncharacterized LOC111093563

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Genome-wide identification and analysis of basic helix-loop-helix domains in dog, Canis lupus familiaris. Wang XH, et al. Mol Genet Genomics, 2015 Apr. PMID 25403511

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables DNA-binding transcription factor activity, RNA polymerase II-specific IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables RNA polymerase II transcription regulatory region sequence-specific DNA binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein dimerization activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in regulation of transcription by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
single-minded homolog 2; LOW QUALITY PROTEIN: single-minded homolog 2
Names
single-minded family bHLH transcription factor 2

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051835.1 Reference ROS_Cfam_1.0

    Range
    31182551..31236268
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038443478.1 → XP_038299406.1  single-minded homolog 2

    UniProtKB/TrEMBL
    A0A8C0LKS6, A0A8C0TCM2, A0A8I3PUA3
    Related
    ENSCAFP00845038275.1, ENSCAFT00845048781.1
    Conserved Domains (4) summary
    smart00091
    Location:79 → 144
    PAS; PAS domain
    pfam08447
    Location:243 → 329
    PAS_3; PAS fold
    cd19739
    Location:1 → 74
    bHLH-PAS_SIM2; basic helix-loop-helix-Per-ARNT-Sim (bHLH-PAS) domain found in single-minded homolog 2 (SIM2) and similar proteins
    pfam06621
    Location:359 → 554
    SIM_C; Single-minded protein C-terminus

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049291.1 Alternate UMICH_Zoey_3.1

    Range
    31050827..31104585
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038517892.1 → XP_038373820.1  single-minded homolog 2

    Conserved Domains (4) summary
    smart00091
    Location:79 → 144
    PAS; PAS domain
    pfam08447
    Location:243 → 329
    PAS_3; PAS fold
    cd19739
    Location:1 → 74
    bHLH-PAS_SIM2; basic helix-loop-helix-Per-ARNT-Sim (bHLH-PAS) domain found in single-minded homolog 2 (SIM2) and similar proteins
    pfam06621
    Location:359 → 554
    SIM_C; Single-minded protein C-terminus

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049772.1 Alternate UNSW_CanFamBas_1.0

    Range
    31063591..31118290
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038645841.1 → XP_038501769.1  LOW QUALITY PROTEIN: single-minded homolog 2

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049252.1 Alternate UU_Cfam_GSD_1.0

    Range
    31553961..31607783
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038581465.1 → XP_038437393.1  LOW QUALITY PROTEIN: single-minded homolog 2

    UniProtKB/TrEMBL
    A0A8C0LKS6, A0A8C0TCM2, A0A8I3PUA3
    Conserved Domains (4) summary
    smart00091
    Location:79 → 144
    PAS; PAS domain
    pfam08447
    Location:243 → 329
    PAS_3; PAS fold
    cd19739
    Location:1 → 74
    bHLH-PAS_SIM2; basic helix-loop-helix-Per-ARNT-Sim (bHLH-PAS) domain found in single-minded homolog 2 (SIM2) and similar proteins
    pfam06621
    Location:359 → 554
    SIM_C; Single-minded protein C-terminus

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006613.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    30940849..30994549
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038461665.1 → XP_038317593.1  single-minded homolog 2

    UniProtKB/TrEMBL
    A0A8C0LKS6, A0A8C0TCM2, A0A8I3PUA3
    Conserved Domains (4) summary
    smart00091
    Location:79 → 144
    PAS; PAS domain
    pfam08447
    Location:243 → 329
    PAS_3; PAS fold
    cd19739
    Location:1 → 74
    bHLH-PAS_SIM2; basic helix-loop-helix-Per-ARNT-Sim (bHLH-PAS) domain found in single-minded homolog 2 (SIM2) and similar proteins
    pfam06621
    Location:359 → 554
    SIM_C; Single-minded protein C-terminus
Nucleotide Protein
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