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MLX MAX dimerization protein MLX [ Canis lupus familiaris (dog) ]

Gene ID: 607668, updated on 25-Jul-2026
Official Symbol
MLXprovided by VGNC
Official Full Name
MAX dimerization protein MLXprovided by VGNC
Primary source
VGNC:VGNC:43267
See related
RGD:12383213
Gene type
protein coding
RefSeq status
MODEL
Organism
Canis lupus familiaris
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Also known as
TF4
Orthologs
all
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Try the new Transcripts and proteins table
See MLX in Genome Data Viewer
Location:
chromosome: 9
Exon count:
8
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) 9 NC_051813.1 (21110183..21114741, complement)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 9 NC_006591.4 (19853081..19857639, complement)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 9 NC_049230.1 (20265296..20269857, complement)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) 9 NC_049269.1 (19896017..19900567, complement)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 9 NC_049750.1 (20160949..20165810, complement)

Chromosome 9 - NC_051813.1Genomic Context describing neighboring genes Neighboring gene tubulin, gamma 1 Neighboring gene reticulophagy regulator family member 3 Neighboring gene PSMC3 interacting protein Neighboring gene Coenzyme A synthase Neighboring gene hydroxysteroid 17-beta dehydrogenase 1

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. Genome-wide identification and analysis of basic helix-loop-helix domains in dog, Canis lupus familiaris. Wang XH, et al. Mol Genet Genomics, 2015 Apr. PMID 25403511
  2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables DNA-binding transcription factor activity, RNA polymerase II-specific IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein dimerization activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in regulation of transcription by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 
Preferred Names
max-like protein X
Names
MAX-like protein X
MLX, MAX dimerization protein

NEW Try the new Transcript table

RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051813.1 Reference ROS_Cfam_1.0

    Range
    21110183..21114741 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038676426.1 → XP_038532354.1  max-like protein X isoform X5

    UniProtKB/TrEMBL
    A0A8C0KKL0
    Conserved Domains (1) summary
    cd19687
    Location:95 → 171
    bHLHzip_Mlx; basic Helix-Loop-Helix-zipper (bHLHzip) domain found in Max-like protein X (Mlx) and similar proteins

  2. XM_038676425.1 → XP_038532353.1  max-like protein X isoform X4

    UniProtKB/TrEMBL
    A0A8C0KLW2
    Conserved Domains (1) summary
    cd19687
    Location:45 → 121
    bHLHzip_Mlx; basic Helix-Loop-Helix-zipper (bHLHzip) domain found in Max-like protein X (Mlx) and similar proteins

  3. XM_038676424.1 → XP_038532352.1  max-like protein X isoform X3

    UniProtKB/TrEMBL
    A0A8C0KKL0
    Conserved Domains (1) summary
    cd19687
    Location:75 → 151
    bHLHzip_Mlx; basic Helix-Loop-Helix-zipper (bHLHzip) domain found in Max-like protein X (Mlx) and similar proteins

  4. XM_038676423.1 → XP_038532351.1  max-like protein X isoform X2

    Conserved Domains (1) summary
    cd19687
    Location:99 → 175
    bHLHzip_Mlx; basic Helix-Loop-Helix-zipper (bHLHzip) domain found in Max-like protein X (Mlx) and similar proteins

  5. XM_038676422.1 → XP_038532350.1  max-like protein X isoform X1

    UniProtKB/TrEMBL
    A0A8C0KKL0, A0A8C0R0L1
    Conserved Domains (1) summary
    cd19687
    Location:129 → 205
    bHLHzip_Mlx; basic Helix-Loop-Helix-zipper (bHLHzip) domain found in Max-like protein X (Mlx) and similar proteins

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049269.1 Alternate UMICH_Zoey_3.1

    Range
    19896017..19900567 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038485507.1 → XP_038341435.1  

    Conserved Domains (1) summary
    cd19687
    Location:45 → 121
    bHLHzip_Mlx; basic Helix-Loop-Helix-zipper (bHLHzip) domain found in Max-like protein X (Mlx) and similar proteins

  2. XM_038485506.1 → XP_038341434.1  

    Conserved Domains (1) summary
    cd19687
    Location:75 → 151
    bHLHzip_Mlx; basic Helix-Loop-Helix-zipper (bHLHzip) domain found in Max-like protein X (Mlx) and similar proteins

  3. XM_038485505.1 → XP_038341433.1  

    Conserved Domains (1) summary
    cd19687
    Location:95 → 171
    bHLHzip_Mlx; basic Helix-Loop-Helix-zipper (bHLHzip) domain found in Max-like protein X (Mlx) and similar proteins

  4. XM_038485504.1 → XP_038341432.1  

    Conserved Domains (1) summary
    cd19687
    Location:99 → 175
    bHLHzip_Mlx; basic Helix-Loop-Helix-zipper (bHLHzip) domain found in Max-like protein X (Mlx) and similar proteins

  5. XM_038485503.1 → XP_038341431.1  

    Conserved Domains (1) summary
    cd19687
    Location:129 → 205
    bHLHzip_Mlx; basic Helix-Loop-Helix-zipper (bHLHzip) domain found in Max-like protein X (Mlx) and similar proteins

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049750.1 Alternate UNSW_CanFamBas_1.0

    Range
    20160949..20165810 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038611238.1 → XP_038467166.1  

    Conserved Domains (1) summary
    cd19687
    Location:95 → 171
    bHLHzip_Mlx; basic Helix-Loop-Helix-zipper (bHLHzip) domain found in Max-like protein X (Mlx) and similar proteins

  2. XM_038611237.1 → XP_038467165.1  

    Conserved Domains (1) summary
    cd19687
    Location:45 → 121
    bHLHzip_Mlx; basic Helix-Loop-Helix-zipper (bHLHzip) domain found in Max-like protein X (Mlx) and similar proteins

  3. XM_038611236.1 → XP_038467164.1  

    Conserved Domains (1) summary
    cd19687
    Location:75 → 151
    bHLHzip_Mlx; basic Helix-Loop-Helix-zipper (bHLHzip) domain found in Max-like protein X (Mlx) and similar proteins

  4. XM_038611235.1 → XP_038467163.1  

    Conserved Domains (1) summary
    cd19687
    Location:99 → 175
    bHLHzip_Mlx; basic Helix-Loop-Helix-zipper (bHLHzip) domain found in Max-like protein X (Mlx) and similar proteins

  5. XM_038611234.1 → XP_038467162.1  

    Conserved Domains (1) summary
    cd19687
    Location:129 → 205
    bHLHzip_Mlx; basic Helix-Loop-Helix-zipper (bHLHzip) domain found in Max-like protein X (Mlx) and similar proteins

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049230.1 Alternate UU_Cfam_GSD_1.0

    Range
    20265296..20269857 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038547269.1 → XP_038403197.1  max-like protein X isoform X5

    UniProtKB/TrEMBL
    A0A8C0KKL0
    Conserved Domains (1) summary
    cd19687
    Location:95 → 171
    bHLHzip_Mlx; basic Helix-Loop-Helix-zipper (bHLHzip) domain found in Max-like protein X (Mlx) and similar proteins

  2. XM_038547268.1 → XP_038403196.1  max-like protein X isoform X4

    UniProtKB/TrEMBL
    A0A8C0KLW2
    Conserved Domains (1) summary
    cd19687
    Location:45 → 121
    bHLHzip_Mlx; basic Helix-Loop-Helix-zipper (bHLHzip) domain found in Max-like protein X (Mlx) and similar proteins

  3. XM_038547267.1 → XP_038403195.1  max-like protein X isoform X3

    UniProtKB/TrEMBL
    A0A8C0KKL0
    Conserved Domains (1) summary
    cd19687
    Location:75 → 151
    bHLHzip_Mlx; basic Helix-Loop-Helix-zipper (bHLHzip) domain found in Max-like protein X (Mlx) and similar proteins

  4. XM_038547266.1 → XP_038403194.1  max-like protein X isoform X2

    Conserved Domains (1) summary
    cd19687
    Location:99 → 175
    bHLHzip_Mlx; basic Helix-Loop-Helix-zipper (bHLHzip) domain found in Max-like protein X (Mlx) and similar proteins

  5. XM_038547265.1 → XP_038403193.1  max-like protein X isoform X1

    UniProtKB/TrEMBL
    A0A8C0KKL0, A0A8C0R0L1
    Conserved Domains (1) summary
    cd19687
    Location:129 → 205
    bHLHzip_Mlx; basic Helix-Loop-Helix-zipper (bHLHzip) domain found in Max-like protein X (Mlx) and similar proteins

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006591.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    19853081..19857639 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_022422976.2 → XP_022278684.1  max-like protein X isoform X5

    UniProtKB/TrEMBL
    A0A8C0KKL0
    Conserved Domains (1) summary
    cd19687
    Location:95 → 171
    bHLHzip_Mlx; basic Helix-Loop-Helix-zipper (bHLHzip) domain found in Max-like protein X (Mlx) and similar proteins

  2. XM_003435229.5 → XP_003435277.3  max-like protein X isoform X4

    UniProtKB/TrEMBL
    A0A8C0KLW2
    Conserved Domains (1) summary
    cd19687
    Location:45 → 121
    bHLHzip_Mlx; basic Helix-Loop-Helix-zipper (bHLHzip) domain found in Max-like protein X (Mlx) and similar proteins

  3. XM_003435228.5 → XP_003435276.3  max-like protein X isoform X3

    UniProtKB/TrEMBL
    A0A8C0KKL0
    Conserved Domains (1) summary
    cd19687
    Location:75 → 151
    bHLHzip_Mlx; basic Helix-Loop-Helix-zipper (bHLHzip) domain found in Max-like protein X (Mlx) and similar proteins

  4. XM_005624449.4 → XP_005624506.2  max-like protein X isoform X2

    Conserved Domains (1) summary
    cd19687
    Location:99 → 175
    bHLHzip_Mlx; basic Helix-Loop-Helix-zipper (bHLHzip) domain found in Max-like protein X (Mlx) and similar proteins

  5. XM_844284.6 → XP_849377.3  max-like protein X isoform X1

    UniProtKB/TrEMBL
    A0A8C0KKL0, A0A8C0R0L1
    Conserved Domains (1) summary
    cd19687
    Location:129 → 205
    bHLHzip_Mlx; basic Helix-Loop-Helix-zipper (bHLHzip) domain found in Max-like protein X (Mlx) and similar proteins
Nucleotide Protein
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