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VPS4B vacuolar protein sorting 4 homolog B [ Canis lupus familiaris (dog) ]

Gene ID: 607306, updated on 25-Jul-2026
Official Symbol
VPS4Bprovided by VGNC
Official Full Name
vacuolar protein sorting 4 homolog Bprovided by VGNC
Primary source
VGNC:VGNC:48293
See related
Ensembl:ENSCAFG00845002445 RGD:12178603
Gene type
protein coding
RefSeq status
MODEL
Organism
Canis lupus familiaris
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs
all
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Try the new Transcripts and proteins table
See VPS4B in Genome Data Viewer
Location:
chromosome: 1
Exon count:
12
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) 1 NC_051805.1 (13500614..13534990)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 1 NC_006583.4 (14605156..14639495)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 1 NC_049222.1 (13716838..13751163)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) 1 NC_049261.1 (13538762..13573109)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 1 NC_049742.1 (13468029..13502377)

Chromosome 1 - NC_051805.1Genomic Context describing neighboring genes Neighboring gene serpin family B member 12 Neighboring gene serpin family B member 5 Neighboring gene uncharacterized LOC119870705 Neighboring gene 3-ketodihydrosphingosine reductase Neighboring gene BCL2 apoptosis regulator Neighboring gene uncharacterized LOC111094459

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables ATP hydrolysis activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in endosomal transport IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in vacuole organization IEA
Inferred from Electronic Annotation
more info
 PubMed 
Preferred Names
vacuolar protein sorting-associated protein 4B
Names
vacuolar protein sorting factor 4B
XP_005615402.1
XP_038321178.1
XP_038321179.1
XP_038381780.1
XP_038381782.1
XP_038446091.1
XP_038446092.1
XP_038509917.1
XP_038509918.1
XP_848812.1

NEW Try the new Transcript table

RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051805.1 Reference ROS_Cfam_1.0

    Range
    13500614..13534990
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038653990.1 → XP_038509918.1  vacuolar protein sorting-associated protein 4B

    UniProtKB/TrEMBL
    A0A8C0R2D1, A0A8I3RQP9
    Related
    ENSCAFP00845003449.1, ENSCAFT00845004320.1
    Conserved Domains (4) summary
    pfam09336
    Location:381 → 441
    Vps4_C; Vps4 C terminal oligomerization domain
    pfam17862
    Location:325 → 365
    AAA_lid_3; AAA+ lid domain
    cd19521
    Location:128 → 298
    RecA-like_VPS4; ATPase domain of vacuolar protein sorting-associated protein 4
    cl00299
    Location:7 → 69
    MIT; domain contained within Microtubule Interacting and Trafficking molecules. The MIT domain is found in sorting nexins, the nuclear thiol protease PalBH, the AAA protein spastin and archaebacterial proteins with similar domain architecture, vacuolar ...

  2. XM_038653989.1 → XP_038509917.1  vacuolar protein sorting-associated protein 4B

    UniProtKB/TrEMBL
    A0A8C0R2D1, A0A8I3RQP9
    Related
    ENSCAFP00845003439.1, ENSCAFT00845004309.1
    Conserved Domains (4) summary
    pfam09336
    Location:381 → 441
    Vps4_C; Vps4 C terminal oligomerization domain
    pfam17862
    Location:325 → 365
    AAA_lid_3; AAA+ lid domain
    cd19521
    Location:128 → 298
    RecA-like_VPS4; ATPase domain of vacuolar protein sorting-associated protein 4
    cl00299
    Location:7 → 69
    MIT; domain contained within Microtubule Interacting and Trafficking molecules. The MIT domain is found in sorting nexins, the nuclear thiol protease PalBH, the AAA protein spastin and archaebacterial proteins with similar domain architecture, vacuolar ...

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049261.1 Alternate UMICH_Zoey_3.1

    Range
    13538762..13573109
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038465251.1 → XP_038321179.1  

    Conserved Domains (4) summary
    pfam09336
    Location:381 → 441
    Vps4_C; Vps4 C terminal oligomerization domain
    pfam17862
    Location:325 → 365
    AAA_lid_3; AAA+ lid domain
    cd19521
    Location:128 → 298
    RecA-like_VPS4; ATPase domain of vacuolar protein sorting-associated protein 4
    cl00299
    Location:7 → 69
    MIT; domain contained within Microtubule Interacting and Trafficking molecules. The MIT domain is found in sorting nexins, the nuclear thiol protease PalBH, the AAA protein spastin and archaebacterial proteins with similar domain architecture, vacuolar ...

  2. XM_038465250.1 → XP_038321178.1  

    Conserved Domains (4) summary
    pfam09336
    Location:381 → 441
    Vps4_C; Vps4 C terminal oligomerization domain
    pfam17862
    Location:325 → 365
    AAA_lid_3; AAA+ lid domain
    cd19521
    Location:128 → 298
    RecA-like_VPS4; ATPase domain of vacuolar protein sorting-associated protein 4
    cl00299
    Location:7 → 69
    MIT; domain contained within Microtubule Interacting and Trafficking molecules. The MIT domain is found in sorting nexins, the nuclear thiol protease PalBH, the AAA protein spastin and archaebacterial proteins with similar domain architecture, vacuolar ...

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049742.1 Alternate UNSW_CanFamBas_1.0

    Range
    13468029..13502377
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038590164.1 → XP_038446092.1  

    Conserved Domains (4) summary
    pfam09336
    Location:381 → 441
    Vps4_C; Vps4 C terminal oligomerization domain
    pfam17862
    Location:325 → 365
    AAA_lid_3; AAA+ lid domain
    cd19521
    Location:128 → 298
    RecA-like_VPS4; ATPase domain of vacuolar protein sorting-associated protein 4
    cl00299
    Location:7 → 69
    MIT; domain contained within Microtubule Interacting and Trafficking molecules. The MIT domain is found in sorting nexins, the nuclear thiol protease PalBH, the AAA protein spastin and archaebacterial proteins with similar domain architecture, vacuolar ...

  2. XM_038590163.1 → XP_038446091.1  

    Conserved Domains (4) summary
    pfam09336
    Location:381 → 441
    Vps4_C; Vps4 C terminal oligomerization domain
    pfam17862
    Location:325 → 365
    AAA_lid_3; AAA+ lid domain
    cd19521
    Location:128 → 298
    RecA-like_VPS4; ATPase domain of vacuolar protein sorting-associated protein 4
    cl00299
    Location:7 → 69
    MIT; domain contained within Microtubule Interacting and Trafficking molecules. The MIT domain is found in sorting nexins, the nuclear thiol protease PalBH, the AAA protein spastin and archaebacterial proteins with similar domain architecture, vacuolar ...

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049222.1 Alternate UU_Cfam_GSD_1.0

    Range
    13716838..13751163
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038525854.1 → XP_038381782.1  vacuolar protein sorting-associated protein 4B

    UniProtKB/TrEMBL
    A0A8C0R2D1, A0A8I3RQP9
    Conserved Domains (4) summary
    pfam09336
    Location:381 → 441
    Vps4_C; Vps4 C terminal oligomerization domain
    pfam17862
    Location:325 → 365
    AAA_lid_3; AAA+ lid domain
    cd19521
    Location:128 → 298
    RecA-like_VPS4; ATPase domain of vacuolar protein sorting-associated protein 4
    cl00299
    Location:7 → 69
    MIT; domain contained within Microtubule Interacting and Trafficking molecules. The MIT domain is found in sorting nexins, the nuclear thiol protease PalBH, the AAA protein spastin and archaebacterial proteins with similar domain architecture, vacuolar ...

  2. XM_038525852.1 → XP_038381780.1  vacuolar protein sorting-associated protein 4B

    UniProtKB/TrEMBL
    A0A8C0R2D1, A0A8I3RQP9
    Conserved Domains (4) summary
    pfam09336
    Location:381 → 441
    Vps4_C; Vps4 C terminal oligomerization domain
    pfam17862
    Location:325 → 365
    AAA_lid_3; AAA+ lid domain
    cd19521
    Location:128 → 298
    RecA-like_VPS4; ATPase domain of vacuolar protein sorting-associated protein 4
    cl00299
    Location:7 → 69
    MIT; domain contained within Microtubule Interacting and Trafficking molecules. The MIT domain is found in sorting nexins, the nuclear thiol protease PalBH, the AAA protein spastin and archaebacterial proteins with similar domain architecture, vacuolar ...

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006583.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    14605156..14639495
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005615345.4 → XP_005615402.1  vacuolar protein sorting-associated protein 4B

    See identical proteins and their annotated locations for XP_005615402.1

    UniProtKB/TrEMBL
    A0A8C0R2D1, A0A8I3RQP9
    Conserved Domains (4) summary
    pfam09336
    Location:381 → 441
    Vps4_C; Vps4 C terminal oligomerization domain
    pfam17862
    Location:325 → 365
    AAA_lid_3; AAA+ lid domain
    cd19521
    Location:128 → 298
    RecA-like_VPS4; ATPase domain of vacuolar protein sorting-associated protein 4
    cl00299
    Location:7 → 69
    MIT; domain contained within Microtubule Interacting and Trafficking molecules. The MIT domain is found in sorting nexins, the nuclear thiol protease PalBH, the AAA protein spastin and archaebacterial proteins with similar domain architecture, vacuolar ...

  2. XM_843719.6 → XP_848812.1  vacuolar protein sorting-associated protein 4B

    See identical proteins and their annotated locations for XP_848812.1

    UniProtKB/TrEMBL
    A0A8C0R2D1, A0A8I3RQP9
    Conserved Domains (4) summary
    pfam09336
    Location:381 → 441
    Vps4_C; Vps4 C terminal oligomerization domain
    pfam17862
    Location:325 → 365
    AAA_lid_3; AAA+ lid domain
    cd19521
    Location:128 → 298
    RecA-like_VPS4; ATPase domain of vacuolar protein sorting-associated protein 4
    cl00299
    Location:7 → 69
    MIT; domain contained within Microtubule Interacting and Trafficking molecules. The MIT domain is found in sorting nexins, the nuclear thiol protease PalBH, the AAA protein spastin and archaebacterial proteins with similar domain architecture, vacuolar ...
Nucleotide Protein
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