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MTMR2 myotubularin related protein 2 [ Canis lupus familiaris (dog) ]

Gene ID: 606918, updated on 25-Jul-2026
Official Symbol
MTMR2provided by VGNC
Official Full Name
myotubularin related protein 2provided by VGNC
Primary source
VGNC:VGNC:43483
See related
Ensembl:ENSCAFG00845017531 RGD:12210659
Gene type
protein coding
RefSeq status
MODEL
Organism
Canis lupus familiaris
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs
all
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See MTMR2 in Genome Data Viewer
Location:
chromosome: 21
Exon count:
20
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) 21 NC_051825.1 (5366974..5491223)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 21 NC_006603.4 (5205909..5327596)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 21 NC_049242.1 (5273521..5395231)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) 21 NC_049281.1 (5164226..5285897)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 21 NC_049762.1 (5225833..5347545)

Chromosome 21 - NC_051825.1Genomic Context describing neighboring genes Neighboring gene mastermind like transcriptional coactivator 2 Neighboring gene small nucleolar RNA SNORA11 Neighboring gene uncharacterized LOC106560166 Neighboring gene centrosomal protein 57 Neighboring gene family with sequence similarity 76 member B Neighboring gene uncharacterized LOC111091478 Neighboring gene nucleoside diphosphate kinase A-like

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in dephosphorylation IEA
Inferred from Electronic Annotation
more info
 PubMed 
Preferred Names
myotubularin-related protein 2
XP_005633385.1
XP_005633386.1
XP_005633387.1
XP_005633388.1
XP_013977931.1
XP_022263173.1
XP_038285619.1
XP_038285620.1
XP_038285621.1
XP_038285622.1
XP_038285623.1
XP_038285624.1
XP_038285625.1
XP_038312098.1
XP_038312099.1
XP_038361036.1
XP_038361037.1
XP_038361038.1
XP_038361039.1
XP_038361040.1
XP_038361041.1
XP_038361042.1
XP_038361043.1
XP_038424157.1
XP_038424158.1
XP_038424159.1
XP_038424160.1
XP_038424161.1
XP_038424162.1
XP_038424163.1
XP_038424164.1
XP_038488298.1
XP_038488299.1
XP_038488300.1
XP_038488301.1
XP_038488302.1
XP_038488303.1
XP_038488304.1
XP_038488305.1

NEW Try the new Transcript table

RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051825.1 Reference ROS_Cfam_1.0

    Range
    5366974..5491223
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038429692.1 → XP_038285620.1  myotubularin-related protein 2 isoform X2

    UniProtKB/TrEMBL
    A0A8C0KV46
    Conserved Domains (2) summary
    pfam06602
    Location:202 → 459
    Myotub-related; Myotubularin-like phosphatase domain
    cl17171
    Location:73 → 187
    PH-like; Pleckstrin homology-like domain

  2. XM_038429691.1 → XP_038285619.1  myotubularin-related protein 2 isoform X1

    UniProtKB/TrEMBL
    A0A8C0KV46
    Related
    ENSCAFP00845024345.1, ENSCAFT00845031077.1
    Conserved Domains (2) summary
    pfam06602
    Location:202 → 528
    Myotub-related; Myotubularin-like phosphatase domain
    cl17171
    Location:73 → 187
    PH-like; Pleckstrin homology-like domain

  3. XM_038429694.1 → XP_038285622.1  myotubularin-related protein 2 isoform X3

    UniProtKB/TrEMBL
    A0A8C0KVJ4
    Conserved Domains (2) summary
    pfam06602
    Location:130 → 456
    Myotub-related; Myotubularin-like phosphatase domain
    cl17171
    Location:1 → 115
    PH-like; Pleckstrin homology-like domain

  4. XM_038429695.1 → XP_038285623.1  myotubularin-related protein 2 isoform X3

    UniProtKB/TrEMBL
    A0A8C0KVJ4
    Conserved Domains (2) summary
    pfam06602
    Location:130 → 456
    Myotub-related; Myotubularin-like phosphatase domain
    cl17171
    Location:1 → 115
    PH-like; Pleckstrin homology-like domain

  5. XM_038429693.1 → XP_038285621.1  myotubularin-related protein 2 isoform X3

    UniProtKB/TrEMBL
    A0A8C0KVJ4
    Related
    ENSCAFP00845024442.1, ENSCAFT00845031223.1
    Conserved Domains (2) summary
    pfam06602
    Location:130 → 456
    Myotub-related; Myotubularin-like phosphatase domain
    cl17171
    Location:1 → 115
    PH-like; Pleckstrin homology-like domain

  6. XM_038429697.1 → XP_038285625.1  myotubularin-related protein 2 isoform X3

    UniProtKB/TrEMBL
    A0A8C0KVJ4
    Conserved Domains (2) summary
    pfam06602
    Location:130 → 456
    Myotub-related; Myotubularin-like phosphatase domain
    cl17171
    Location:1 → 115
    PH-like; Pleckstrin homology-like domain

  7. XM_038429696.1 → XP_038285624.1  myotubularin-related protein 2 isoform X3

    UniProtKB/TrEMBL
    A0A8C0KVJ4
    Conserved Domains (2) summary
    pfam06602
    Location:130 → 456
    Myotub-related; Myotubularin-like phosphatase domain
    cl17171
    Location:1 → 115
    PH-like; Pleckstrin homology-like domain

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049281.1 Alternate UMICH_Zoey_3.1

    Range
    5164226..5285897
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038505109.1 → XP_038361037.1  

    Conserved Domains (2) summary
    pfam06602
    Location:202 → 459
    Myotub-related; Myotubularin-like phosphatase domain
    cl17171
    Location:73 → 187
    PH-like; Pleckstrin homology-like domain

  2. XM_038505108.1 → XP_038361036.1  

    Conserved Domains (2) summary
    pfam06602
    Location:202 → 528
    Myotub-related; Myotubularin-like phosphatase domain
    cl17171
    Location:73 → 187
    PH-like; Pleckstrin homology-like domain

  3. XM_038505112.1 → XP_038361040.1  

    Conserved Domains (2) summary
    pfam06602
    Location:130 → 456
    Myotub-related; Myotubularin-like phosphatase domain
    cl17171
    Location:1 → 115
    PH-like; Pleckstrin homology-like domain

  4. XM_038505113.1 → XP_038361041.1  

    Conserved Domains (2) summary
    pfam06602
    Location:130 → 456
    Myotub-related; Myotubularin-like phosphatase domain
    cl17171
    Location:1 → 115
    PH-like; Pleckstrin homology-like domain

  5. XM_038505110.1 → XP_038361038.1  

    Conserved Domains (2) summary
    pfam06602
    Location:130 → 456
    Myotub-related; Myotubularin-like phosphatase domain
    cl17171
    Location:1 → 115
    PH-like; Pleckstrin homology-like domain

  6. XM_038505111.1 → XP_038361039.1  

    Conserved Domains (2) summary
    pfam06602
    Location:130 → 456
    Myotub-related; Myotubularin-like phosphatase domain
    cl17171
    Location:1 → 115
    PH-like; Pleckstrin homology-like domain

  7. XM_038505115.1 → XP_038361043.1  

    Conserved Domains (2) summary
    pfam06602
    Location:130 → 456
    Myotub-related; Myotubularin-like phosphatase domain
    cl17171
    Location:1 → 115
    PH-like; Pleckstrin homology-like domain

  8. XM_038505114.1 → XP_038361042.1  

    Conserved Domains (2) summary
    pfam06602
    Location:130 → 456
    Myotub-related; Myotubularin-like phosphatase domain
    cl17171
    Location:1 → 115
    PH-like; Pleckstrin homology-like domain

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049762.1 Alternate UNSW_CanFamBas_1.0

    Range
    5225833..5347545
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038632371.1 → XP_038488299.1  

    Conserved Domains (2) summary
    pfam06602
    Location:202 → 459
    Myotub-related; Myotubularin-like phosphatase domain
    cl17171
    Location:73 → 187
    PH-like; Pleckstrin homology-like domain

  2. XM_038632370.1 → XP_038488298.1  

    Conserved Domains (2) summary
    pfam06602
    Location:202 → 528
    Myotub-related; Myotubularin-like phosphatase domain
    cl17171
    Location:73 → 187
    PH-like; Pleckstrin homology-like domain

  3. XM_038632374.1 → XP_038488302.1  

    Conserved Domains (2) summary
    pfam06602
    Location:130 → 456
    Myotub-related; Myotubularin-like phosphatase domain
    cl17171
    Location:1 → 115
    PH-like; Pleckstrin homology-like domain

  4. XM_038632375.1 → XP_038488303.1  

    Conserved Domains (2) summary
    pfam06602
    Location:130 → 456
    Myotub-related; Myotubularin-like phosphatase domain
    cl17171
    Location:1 → 115
    PH-like; Pleckstrin homology-like domain

  5. XM_038632372.1 → XP_038488300.1  

    Conserved Domains (2) summary
    pfam06602
    Location:130 → 456
    Myotub-related; Myotubularin-like phosphatase domain
    cl17171
    Location:1 → 115
    PH-like; Pleckstrin homology-like domain

  6. XM_038632373.1 → XP_038488301.1  

    Conserved Domains (2) summary
    pfam06602
    Location:130 → 456
    Myotub-related; Myotubularin-like phosphatase domain
    cl17171
    Location:1 → 115
    PH-like; Pleckstrin homology-like domain

  7. XM_038632377.1 → XP_038488305.1  

    Conserved Domains (2) summary
    pfam06602
    Location:130 → 456
    Myotub-related; Myotubularin-like phosphatase domain
    cl17171
    Location:1 → 115
    PH-like; Pleckstrin homology-like domain

  8. XM_038632376.1 → XP_038488304.1  

    Conserved Domains (2) summary
    pfam06602
    Location:130 → 456
    Myotub-related; Myotubularin-like phosphatase domain
    cl17171
    Location:1 → 115
    PH-like; Pleckstrin homology-like domain

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049242.1 Alternate UU_Cfam_GSD_1.0

    Range
    5273521..5395231
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038568230.1 → XP_038424158.1  myotubularin-related protein 2 isoform X2

    UniProtKB/TrEMBL
    A0A8C0KV46
    Conserved Domains (2) summary
    pfam06602
    Location:202 → 459
    Myotub-related; Myotubularin-like phosphatase domain
    cl17171
    Location:73 → 187
    PH-like; Pleckstrin homology-like domain

  2. XM_038568229.1 → XP_038424157.1  myotubularin-related protein 2 isoform X1

    UniProtKB/TrEMBL
    A0A8C0KV46
    Conserved Domains (2) summary
    pfam06602
    Location:202 → 528
    Myotub-related; Myotubularin-like phosphatase domain
    cl17171
    Location:73 → 187
    PH-like; Pleckstrin homology-like domain

  3. XM_038568233.1 → XP_038424161.1  myotubularin-related protein 2 isoform X3

    UniProtKB/TrEMBL
    A0A8C0KVJ4
    Conserved Domains (2) summary
    pfam06602
    Location:130 → 456
    Myotub-related; Myotubularin-like phosphatase domain
    cl17171
    Location:1 → 115
    PH-like; Pleckstrin homology-like domain

  4. XM_038568234.1 → XP_038424162.1  myotubularin-related protein 2 isoform X3

    UniProtKB/TrEMBL
    A0A8C0KVJ4
    Conserved Domains (2) summary
    pfam06602
    Location:130 → 456
    Myotub-related; Myotubularin-like phosphatase domain
    cl17171
    Location:1 → 115
    PH-like; Pleckstrin homology-like domain

  5. XM_038568231.1 → XP_038424159.1  myotubularin-related protein 2 isoform X3

    UniProtKB/TrEMBL
    A0A8C0KVJ4
    Conserved Domains (2) summary
    pfam06602
    Location:130 → 456
    Myotub-related; Myotubularin-like phosphatase domain
    cl17171
    Location:1 → 115
    PH-like; Pleckstrin homology-like domain

  6. XM_038568232.1 → XP_038424160.1  myotubularin-related protein 2 isoform X3

    UniProtKB/TrEMBL
    A0A8C0KVJ4
    Conserved Domains (2) summary
    pfam06602
    Location:130 → 456
    Myotub-related; Myotubularin-like phosphatase domain
    cl17171
    Location:1 → 115
    PH-like; Pleckstrin homology-like domain

  7. XM_038568236.1 → XP_038424164.1  myotubularin-related protein 2 isoform X3

    UniProtKB/TrEMBL
    A0A8C0KVJ4
    Conserved Domains (2) summary
    pfam06602
    Location:130 → 456
    Myotub-related; Myotubularin-like phosphatase domain
    cl17171
    Location:1 → 115
    PH-like; Pleckstrin homology-like domain

  8. XM_038568235.1 → XP_038424163.1  myotubularin-related protein 2 isoform X3

    UniProtKB/TrEMBL
    A0A8C0KVJ4
    Conserved Domains (2) summary
    pfam06602
    Location:130 → 456
    Myotub-related; Myotubularin-like phosphatase domain
    cl17171
    Location:1 → 115
    PH-like; Pleckstrin homology-like domain

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006603.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    5205909..5327596
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038456171.1 → XP_038312099.1  myotubularin-related protein 2 isoform X2

    UniProtKB/TrEMBL
    A0A8C0KV46
    Conserved Domains (2) summary
    pfam06602
    Location:202 → 459
    Myotub-related; Myotubularin-like phosphatase domain
    cl17171
    Location:73 → 187
    PH-like; Pleckstrin homology-like domain

  2. XM_038456170.1 → XP_038312098.1  myotubularin-related protein 2 isoform X1

    UniProtKB/TrEMBL
    A0A8C0KV46
    Conserved Domains (2) summary
    pfam06602
    Location:202 → 528
    Myotub-related; Myotubularin-like phosphatase domain
    cl17171
    Location:73 → 187
    PH-like; Pleckstrin homology-like domain

  3. XM_005633330.3 → XP_005633387.1  myotubularin-related protein 2 isoform X3

    See identical proteins and their annotated locations for XP_005633387.1

    UniProtKB/TrEMBL
    A0A8C0KVJ4
    Conserved Domains (2) summary
    pfam06602
    Location:130 → 456
    Myotub-related; Myotubularin-like phosphatase domain
    cl17171
    Location:1 → 115
    PH-like; Pleckstrin homology-like domain

  4. XM_014122456.3 → XP_013977931.1  myotubularin-related protein 2 isoform X3

    UniProtKB/TrEMBL
    A0A8C0KVJ4
    Conserved Domains (2) summary
    pfam06602
    Location:130 → 456
    Myotub-related; Myotubularin-like phosphatase domain
    cl17171
    Location:1 → 115
    PH-like; Pleckstrin homology-like domain

  5. XM_005633328.3 → XP_005633385.1  myotubularin-related protein 2 isoform X3

    See identical proteins and their annotated locations for XP_005633385.1

    UniProtKB/TrEMBL
    A0A8C0KVJ4
    Conserved Domains (2) summary
    pfam06602
    Location:130 → 456
    Myotub-related; Myotubularin-like phosphatase domain
    cl17171
    Location:1 → 115
    PH-like; Pleckstrin homology-like domain

  6. XM_005633329.4 → XP_005633386.1  myotubularin-related protein 2 isoform X3

    See identical proteins and their annotated locations for XP_005633386.1

    UniProtKB/TrEMBL
    A0A8C0KVJ4
    Conserved Domains (2) summary
    pfam06602
    Location:130 → 456
    Myotub-related; Myotubularin-like phosphatase domain
    cl17171
    Location:1 → 115
    PH-like; Pleckstrin homology-like domain

  7. XM_005633331.3 → XP_005633388.1  myotubularin-related protein 2 isoform X3

    See identical proteins and their annotated locations for XP_005633388.1

    UniProtKB/TrEMBL
    A0A8C0KVJ4
    Conserved Domains (2) summary
    pfam06602
    Location:130 → 456
    Myotub-related; Myotubularin-like phosphatase domain
    cl17171
    Location:1 → 115
    PH-like; Pleckstrin homology-like domain

  8. XM_022407465.2 → XP_022263173.1  myotubularin-related protein 2 isoform X3

    UniProtKB/TrEMBL
    A0A8C0KVJ4
    Conserved Domains (2) summary
    pfam06602
    Location:130 → 456
    Myotub-related; Myotubularin-like phosphatase domain
    cl17171
    Location:1 → 115
    PH-like; Pleckstrin homology-like domain
Nucleotide Protein
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