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ADAMTS9 ADAM metallopeptidase with thrombospondin type 1 motif 9 [ Canis lupus familiaris (dog) ]

Gene ID: 606847, updated on 25-Jul-2026
Official Symbol
ADAMTS9provided by VGNC
Official Full Name
ADAM metallopeptidase with thrombospondin type 1 motif 9provided by VGNC
Primary source
VGNC:VGNC:37605
See related
Ensembl:ENSCAFG00845012850 RGD:12358317
Gene type
protein coding
RefSeq status
MODEL
Organism
Canis lupus familiaris
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs
all
Try the new Gene page
Try the new Transcripts and proteins table
See ADAMTS9 in Genome Data Viewer
Location:
chromosome: 20
Exon count:
40
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) 20 NC_051824.1 (26630243..26790304)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 20 NC_006602.4 (26514671..26674068)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 20 NC_049241.1 (26736222..26895640)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) 20 NC_049280.1 (26324394..26484009)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 20 NC_049761.1 (26676416..26835956)

Chromosome 20 - NC_051824.1Genomic Context describing neighboring genes Neighboring gene U4atac minor spliceosomal RNA Neighboring gene uncharacterized LOC111091286 Neighboring gene uncharacterized LOC119864667 Neighboring gene uncharacterized LOC111091285 Neighboring gene U6 spliceosomal RNA Neighboring gene prickle planar cell polarity protein 2

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables metalloendopeptidase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables zinc ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in extracellular matrix organization IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in proteolysis IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in extracellular matrix IEA
Inferred from Electronic Annotation
more info
 PubMed 
Preferred Names
A disintegrin and metalloproteinase with thrombospondin motifs 9

NEW Try the new Transcript table

RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051824.1 Reference ROS_Cfam_1.0

    Range
    26630243..26790304
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038427235.1 → XP_038283163.1  A disintegrin and metalloproteinase with thrombospondin motifs 9 isoform X1

    UniProtKB/TrEMBL
    A0A8C0KDA9, A0A8C0KDG4, A0A8I3NK12
    Related
    ENSCAFP00845017964.1, ENSCAFT00845022915.1
    Conserved Domains (7) summary
    smart00209
    Location:585 → 636
    TSP1; Thrombospondin type 1 repeats
    cd04273
    Location:290 → 493
    ZnMc_ADAMTS_like; Zinc-dependent metalloprotease, ADAMTS_like subgroup. ADAMs (A Disintegrin And Metalloprotease) are glycoproteins, which play roles in cell signaling, cell fusion, and cell-cell interactions. This particular subfamily represents domain architectures that ...
    pfam05986
    Location:747 → 865
    ADAM_spacer1; ADAM-TS Spacer 1
    pfam01562
    Location:49 → 204
    Pep_M12B_propep; Reprolysin family propeptide
    pfam08685
    Location:1733 → 1929
    GON; GON domain
    pfam17771
    Location:508 → 572
    ADAM_CR_2; ADAM cysteine-rich domain
    pfam19030
    Location:1105 → 1159
    TSP1_ADAMTS; Thrombospondin type 1 domain

  2. XM_038427238.1 → XP_038283166.1  A disintegrin and metalloproteinase with thrombospondin motifs 9 isoform X4

    UniProtKB/TrEMBL
    A0A8C0KDD9, A0A8I3NP26
    Related
    ENSCAFP00845018541.1, ENSCAFT00845023619.1
    Conserved Domains (7) summary
    smart00209
    Location:585 → 636
    TSP1; Thrombospondin type 1 repeats
    cd04273
    Location:290 → 493
    ZnMc_ADAMTS_like; Zinc-dependent metalloprotease, ADAMTS_like subgroup. ADAMs (A Disintegrin And Metalloprotease) are glycoproteins, which play roles in cell signaling, cell fusion, and cell-cell interactions. This particular subfamily represents domain architectures that ...
    pfam05986
    Location:747 → 865
    ADAM_spacer1; ADAM-TS Spacer 1
    pfam01562
    Location:49 → 204
    Pep_M12B_propep; Reprolysin family propeptide
    pfam08685
    Location:1675 → 1871
    GON; GON domain
    pfam17771
    Location:508 → 572
    ADAM_CR_2; ADAM cysteine-rich domain
    pfam19030
    Location:1105 → 1159
    TSP1_ADAMTS; Thrombospondin type 1 domain

  3. XM_038427237.1 → XP_038283165.1  A disintegrin and metalloproteinase with thrombospondin motifs 9 isoform X3

    UniProtKB/TrEMBL
    A0A8C0KDD9, A0A8I3NZ51
    Related
    ENSCAFP00845018378.1, ENSCAFT00845023420.1
    Conserved Domains (7) summary
    smart00209
    Location:585 → 636
    TSP1; Thrombospondin type 1 repeats
    cd04273
    Location:290 → 493
    ZnMc_ADAMTS_like; Zinc-dependent metalloprotease, ADAMTS_like subgroup. ADAMs (A Disintegrin And Metalloprotease) are glycoproteins, which play roles in cell signaling, cell fusion, and cell-cell interactions. This particular subfamily represents domain architectures that ...
    pfam05986
    Location:747 → 865
    ADAM_spacer1; ADAM-TS Spacer 1
    pfam01562
    Location:49 → 204
    Pep_M12B_propep; Reprolysin family propeptide
    pfam08685
    Location:1677 → 1873
    GON; GON domain
    pfam17771
    Location:508 → 572
    ADAM_CR_2; ADAM cysteine-rich domain
    pfam19030
    Location:1105 → 1159
    TSP1_ADAMTS; Thrombospondin type 1 domain

  4. XM_038427236.1 → XP_038283164.1  A disintegrin and metalloproteinase with thrombospondin motifs 9 isoform X2

    UniProtKB/TrEMBL
    A0A8C0KDA9, A0A8I3NP62
    Related
    ENSCAFP00845018099.1, ENSCAFT00845023085.1
    Conserved Domains (7) summary
    smart00209
    Location:557 → 608
    TSP1; Thrombospondin type 1 repeats
    cd04273
    Location:290 → 465
    ZnMc_ADAMTS_like; Zinc-dependent metalloprotease, ADAMTS_like subgroup. ADAMs (A Disintegrin And Metalloprotease) are glycoproteins, which play roles in cell signaling, cell fusion, and cell-cell interactions. This particular subfamily represents domain architectures that ...
    pfam05986
    Location:719 → 837
    ADAM_spacer1; ADAM-TS Spacer 1
    pfam01562
    Location:49 → 204
    Pep_M12B_propep; Reprolysin family propeptide
    pfam08685
    Location:1705 → 1901
    GON; GON domain
    pfam17771
    Location:480 → 544
    ADAM_CR_2; ADAM cysteine-rich domain
    pfam19030
    Location:1077 → 1131
    TSP1_ADAMTS; Thrombospondin type 1 domain

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049280.1 Alternate UMICH_Zoey_3.1

    Range
    26324394..26484009
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038502965.1 → XP_038358893.1  

    Conserved Domains (7) summary
    smart00209
    Location:585 → 636
    TSP1; Thrombospondin type 1 repeats
    cd04273
    Location:290 → 493
    ZnMc_ADAMTS_like; Zinc-dependent metalloprotease, ADAMTS_like subgroup. ADAMs (A Disintegrin And Metalloprotease) are glycoproteins, which play roles in cell signaling, cell fusion, and cell-cell interactions. This particular subfamily represents domain architectures that ...
    pfam05986
    Location:747 → 865
    ADAM_spacer1; ADAM-TS Spacer 1
    pfam01562
    Location:49 → 204
    Pep_M12B_propep; Reprolysin family propeptide
    pfam08685
    Location:1733 → 1929
    GON; GON domain
    pfam17771
    Location:508 → 572
    ADAM_CR_2; ADAM cysteine-rich domain
    pfam19030
    Location:1105 → 1159
    TSP1_ADAMTS; Thrombospondin type 1 domain

  2. XM_038502968.1 → XP_038358896.1  

    Conserved Domains (7) summary
    smart00209
    Location:585 → 636
    TSP1; Thrombospondin type 1 repeats
    cd04273
    Location:290 → 493
    ZnMc_ADAMTS_like; Zinc-dependent metalloprotease, ADAMTS_like subgroup. ADAMs (A Disintegrin And Metalloprotease) are glycoproteins, which play roles in cell signaling, cell fusion, and cell-cell interactions. This particular subfamily represents domain architectures that ...
    pfam05986
    Location:747 → 865
    ADAM_spacer1; ADAM-TS Spacer 1
    pfam01562
    Location:49 → 204
    Pep_M12B_propep; Reprolysin family propeptide
    pfam08685
    Location:1675 → 1871
    GON; GON domain
    pfam17771
    Location:508 → 572
    ADAM_CR_2; ADAM cysteine-rich domain
    pfam19030
    Location:1105 → 1159
    TSP1_ADAMTS; Thrombospondin type 1 domain

  3. XM_038502967.1 → XP_038358895.1  

    Conserved Domains (7) summary
    smart00209
    Location:585 → 636
    TSP1; Thrombospondin type 1 repeats
    cd04273
    Location:290 → 493
    ZnMc_ADAMTS_like; Zinc-dependent metalloprotease, ADAMTS_like subgroup. ADAMs (A Disintegrin And Metalloprotease) are glycoproteins, which play roles in cell signaling, cell fusion, and cell-cell interactions. This particular subfamily represents domain architectures that ...
    pfam05986
    Location:747 → 865
    ADAM_spacer1; ADAM-TS Spacer 1
    pfam01562
    Location:49 → 204
    Pep_M12B_propep; Reprolysin family propeptide
    pfam08685
    Location:1677 → 1873
    GON; GON domain
    pfam17771
    Location:508 → 572
    ADAM_CR_2; ADAM cysteine-rich domain
    pfam19030
    Location:1105 → 1159
    TSP1_ADAMTS; Thrombospondin type 1 domain

  4. XM_038502966.1 → XP_038358894.1  

    Conserved Domains (7) summary
    smart00209
    Location:557 → 608
    TSP1; Thrombospondin type 1 repeats
    cd04273
    Location:290 → 465
    ZnMc_ADAMTS_like; Zinc-dependent metalloprotease, ADAMTS_like subgroup. ADAMs (A Disintegrin And Metalloprotease) are glycoproteins, which play roles in cell signaling, cell fusion, and cell-cell interactions. This particular subfamily represents domain architectures that ...
    pfam05986
    Location:719 → 837
    ADAM_spacer1; ADAM-TS Spacer 1
    pfam01562
    Location:49 → 204
    Pep_M12B_propep; Reprolysin family propeptide
    pfam08685
    Location:1705 → 1901
    GON; GON domain
    pfam17771
    Location:480 → 544
    ADAM_CR_2; ADAM cysteine-rich domain
    pfam19030
    Location:1077 → 1131
    TSP1_ADAMTS; Thrombospondin type 1 domain

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049761.1 Alternate UNSW_CanFamBas_1.0

    Range
    26676416..26835956
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038630051.1 → XP_038485979.1  

    Conserved Domains (7) summary
    smart00209
    Location:585 → 636
    TSP1; Thrombospondin type 1 repeats
    cd04273
    Location:290 → 493
    ZnMc_ADAMTS_like; Zinc-dependent metalloprotease, ADAMTS_like subgroup. ADAMs (A Disintegrin And Metalloprotease) are glycoproteins, which play roles in cell signaling, cell fusion, and cell-cell interactions. This particular subfamily represents domain architectures that ...
    pfam05986
    Location:747 → 865
    ADAM_spacer1; ADAM-TS Spacer 1
    pfam01562
    Location:49 → 204
    Pep_M12B_propep; Reprolysin family propeptide
    pfam08685
    Location:1733 → 1929
    GON; GON domain
    pfam17771
    Location:508 → 572
    ADAM_CR_2; ADAM cysteine-rich domain
    pfam19030
    Location:1105 → 1159
    TSP1_ADAMTS; Thrombospondin type 1 domain

  2. XM_038630054.1 → XP_038485982.1  

    Conserved Domains (7) summary
    smart00209
    Location:585 → 636
    TSP1; Thrombospondin type 1 repeats
    cd04273
    Location:290 → 493
    ZnMc_ADAMTS_like; Zinc-dependent metalloprotease, ADAMTS_like subgroup. ADAMs (A Disintegrin And Metalloprotease) are glycoproteins, which play roles in cell signaling, cell fusion, and cell-cell interactions. This particular subfamily represents domain architectures that ...
    pfam05986
    Location:747 → 865
    ADAM_spacer1; ADAM-TS Spacer 1
    pfam01562
    Location:49 → 204
    Pep_M12B_propep; Reprolysin family propeptide
    pfam08685
    Location:1675 → 1871
    GON; GON domain
    pfam17771
    Location:508 → 572
    ADAM_CR_2; ADAM cysteine-rich domain
    pfam19030
    Location:1105 → 1159
    TSP1_ADAMTS; Thrombospondin type 1 domain

  3. XM_038630053.1 → XP_038485981.1  

    Conserved Domains (7) summary
    smart00209
    Location:585 → 636
    TSP1; Thrombospondin type 1 repeats
    cd04273
    Location:290 → 493
    ZnMc_ADAMTS_like; Zinc-dependent metalloprotease, ADAMTS_like subgroup. ADAMs (A Disintegrin And Metalloprotease) are glycoproteins, which play roles in cell signaling, cell fusion, and cell-cell interactions. This particular subfamily represents domain architectures that ...
    pfam05986
    Location:747 → 865
    ADAM_spacer1; ADAM-TS Spacer 1
    pfam01562
    Location:49 → 204
    Pep_M12B_propep; Reprolysin family propeptide
    pfam08685
    Location:1677 → 1873
    GON; GON domain
    pfam17771
    Location:508 → 572
    ADAM_CR_2; ADAM cysteine-rich domain
    pfam19030
    Location:1105 → 1159
    TSP1_ADAMTS; Thrombospondin type 1 domain

  4. XM_038630052.1 → XP_038485980.1  

    Conserved Domains (7) summary
    smart00209
    Location:557 → 608
    TSP1; Thrombospondin type 1 repeats
    cd04273
    Location:290 → 465
    ZnMc_ADAMTS_like; Zinc-dependent metalloprotease, ADAMTS_like subgroup. ADAMs (A Disintegrin And Metalloprotease) are glycoproteins, which play roles in cell signaling, cell fusion, and cell-cell interactions. This particular subfamily represents domain architectures that ...
    pfam05986
    Location:719 → 837
    ADAM_spacer1; ADAM-TS Spacer 1
    pfam01562
    Location:49 → 204
    Pep_M12B_propep; Reprolysin family propeptide
    pfam08685
    Location:1705 → 1901
    GON; GON domain
    pfam17771
    Location:480 → 544
    ADAM_CR_2; ADAM cysteine-rich domain
    pfam19030
    Location:1077 → 1131
    TSP1_ADAMTS; Thrombospondin type 1 domain

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049241.1 Alternate UU_Cfam_GSD_1.0

    Range
    26736222..26895640
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038565917.1 → XP_038421845.1  A disintegrin and metalloproteinase with thrombospondin motifs 9 isoform X1

    UniProtKB/TrEMBL
    A0A8C0KDA9

  2. XM_038565920.1 → XP_038421848.1  A disintegrin and metalloproteinase with thrombospondin motifs 9 isoform X4

    UniProtKB/TrEMBL
    A0A8C0KDD9

  3. XM_038565919.1 → XP_038421847.1  A disintegrin and metalloproteinase with thrombospondin motifs 9 isoform X3

    UniProtKB/TrEMBL
    A0A8C0KDD9

  4. XM_038565918.1 → XP_038421846.1  A disintegrin and metalloproteinase with thrombospondin motifs 9 isoform X2

    UniProtKB/TrEMBL
    A0A8C0KDA9

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006602.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    26514671..26674068
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_843300.6 → XP_848393.1  A disintegrin and metalloproteinase with thrombospondin motifs 9 isoform X1

    UniProtKB/TrEMBL
    A0A8C0KDA9, A0A8C0KDG4, A0A8I3NK12
    Conserved Domains (7) summary
    smart00209
    Location:585 → 636
    TSP1; Thrombospondin type 1 repeats
    cd04273
    Location:290 → 493
    ZnMc_ADAMTS_like; Zinc-dependent metalloprotease, ADAMTS_like subgroup. ADAMs (A Disintegrin And Metalloprotease) are glycoproteins, which play roles in cell signaling, cell fusion, and cell-cell interactions. This particular subfamily represents domain architectures that ...
    pfam05986
    Location:747 → 865
    ADAM_spacer1; ADAM-TS Spacer 1
    pfam01562
    Location:49 → 204
    Pep_M12B_propep; Reprolysin family propeptide
    pfam08685
    Location:1733 → 1929
    GON; GON domain
    pfam17771
    Location:508 → 572
    ADAM_CR_2; ADAM cysteine-rich domain
    pfam19030
    Location:1105 → 1159
    TSP1_ADAMTS; Thrombospondin type 1 domain

  2. XM_022406482.2 → XP_022262190.1  A disintegrin and metalloproteinase with thrombospondin motifs 9 isoform X4

    UniProtKB/TrEMBL
    A0A8C0KDD9, A0A8I3NP26
    Conserved Domains (7) summary
    smart00209
    Location:585 → 636
    TSP1; Thrombospondin type 1 repeats
    cd04273
    Location:290 → 493
    ZnMc_ADAMTS_like; Zinc-dependent metalloprotease, ADAMTS_like subgroup. ADAMs (A Disintegrin And Metalloprotease) are glycoproteins, which play roles in cell signaling, cell fusion, and cell-cell interactions. This particular subfamily represents domain architectures that ...
    pfam05986
    Location:747 → 865
    ADAM_spacer1; ADAM-TS Spacer 1
    pfam01562
    Location:49 → 204
    Pep_M12B_propep; Reprolysin family propeptide
    pfam08685
    Location:1675 → 1871
    GON; GON domain
    pfam17771
    Location:508 → 572
    ADAM_CR_2; ADAM cysteine-rich domain
    pfam19030
    Location:1105 → 1159
    TSP1_ADAMTS; Thrombospondin type 1 domain

  3. XM_014121873.3 → XP_013977348.1  A disintegrin and metalloproteinase with thrombospondin motifs 9 isoform X3

    UniProtKB/TrEMBL
    A0A8C0KDD9, A0A8I3NZ51
    Conserved Domains (7) summary
    smart00209
    Location:585 → 636
    TSP1; Thrombospondin type 1 repeats
    cd04273
    Location:290 → 493
    ZnMc_ADAMTS_like; Zinc-dependent metalloprotease, ADAMTS_like subgroup. ADAMs (A Disintegrin And Metalloprotease) are glycoproteins, which play roles in cell signaling, cell fusion, and cell-cell interactions. This particular subfamily represents domain architectures that ...
    pfam05986
    Location:747 → 865
    ADAM_spacer1; ADAM-TS Spacer 1
    pfam01562
    Location:49 → 204
    Pep_M12B_propep; Reprolysin family propeptide
    pfam08685
    Location:1677 → 1873
    GON; GON domain
    pfam17771
    Location:508 → 572
    ADAM_CR_2; ADAM cysteine-rich domain
    pfam19030
    Location:1105 → 1159
    TSP1_ADAMTS; Thrombospondin type 1 domain

  4. XM_005632347.4 → XP_005632404.1  A disintegrin and metalloproteinase with thrombospondin motifs 9 isoform X2

    UniProtKB/TrEMBL
    A0A8C0KDA9, A0A8I3NP62
    Conserved Domains (7) summary
    smart00209
    Location:557 → 608
    TSP1; Thrombospondin type 1 repeats
    cd04273
    Location:290 → 465
    ZnMc_ADAMTS_like; Zinc-dependent metalloprotease, ADAMTS_like subgroup. ADAMs (A Disintegrin And Metalloprotease) are glycoproteins, which play roles in cell signaling, cell fusion, and cell-cell interactions. This particular subfamily represents domain architectures that ...
    pfam05986
    Location:719 → 837
    ADAM_spacer1; ADAM-TS Spacer 1
    pfam01562
    Location:49 → 204
    Pep_M12B_propep; Reprolysin family propeptide
    pfam08685
    Location:1705 → 1901
    GON; GON domain
    pfam17771
    Location:480 → 544
    ADAM_CR_2; ADAM cysteine-rich domain
    pfam19030
    Location:1077 → 1131
    TSP1_ADAMTS; Thrombospondin type 1 domain
Nucleotide Protein
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