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ATG101 autophagy related 101 [ Homo sapiens (human) ]

Gene ID: 60673, updated on 1-Jun-2020

Summary

Official Symbol
ATG101provided by HGNC
Official Full Name
autophagy related 101provided by HGNC
Primary source
HGNC:HGNC:25679
See related
Ensembl:ENSG00000123395 MIM:615089
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
C12orf44
Expression
Ubiquitous expression in testis (RPKM 16.2), thyroid (RPKM 14.2) and 25 other tissues See more
Orthologs

Genomic context

See ATG101 in Genome Data Viewer
Location:
12q13.13
Exon count:
5
Annotation release Status Assembly Chr Location
109.20200522 current GRCh38.p13 (GCF_000001405.39) 12 NC_000012.12 (52069923..52077495)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 12 NC_000012.11 (52463758..52471279)

Chromosome 12 - NC_000012.12Genomic Context describing neighboring genes Neighboring gene Sharpr-MPRA regulatory region 2055 Neighboring gene nuclear receptor subfamily 4 group A member 1 Neighboring gene uncharacterized LOC107984510 Neighboring gene small integral membrane protein 41 Neighboring gene uncharacterized LOC112268096 Neighboring gene olfactory receptor family 7 subfamily E member 47 pseudogene Neighboring gene uncharacterized LOC105369771

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • FLJ11773

Gene Ontology Provided by GOA

Function Evidence Code Pubs
identical protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
protein-containing complex binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
autophagosome assembly IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
autophagosome assembly IMP
Inferred from Mutant Phenotype
more info
PubMed 
macroautophagy TAS
Traceable Author Statement
more info
 
regulation of macroautophagy TAS
Traceable Author Statement
more info
 
Component Evidence Code Pubs
cytosol TAS
Traceable Author Statement
more info
 
endoplasmic reticulum membrane TAS
Traceable Author Statement
more info
 
phagophore assembly site IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
phagophore assembly site IDA
Inferred from Direct Assay
more info
PubMed 

General protein information

Preferred Names
autophagy-related protein 101
Names
Atg13-interacting protein

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001098673.2NP_001092143.1  autophagy-related protein 101

    See identical proteins and their annotated locations for NP_001092143.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) uses an alternate splice site in the 5' UTR, compared to variant 1. Both variants 1 and 2 encode the same protein.
    Source sequence(s)
    BC005151, BP309508, CB137838
    Consensus CDS
    CCDS8820.1
    UniProtKB/Swiss-Prot
    Q9BSB4
    UniProtKB/TrEMBL
    A0A024R128
    Related
    ENSP00000450088.1, ENST00000553049.5
    Conserved Domains (1) summary
    pfam07855
    Location:9172
    ATG101; Autophagy-related protein 101
  2. NM_021934.4NP_068753.2  autophagy-related protein 101

    See identical proteins and their annotated locations for NP_068753.2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longer transcript. Both variants 1 and 2 encode the same protein.
    Source sequence(s)
    BC005151, CB137838
    Consensus CDS
    CCDS8820.1
    UniProtKB/Swiss-Prot
    Q9BSB4
    UniProtKB/TrEMBL
    A0A024R128
    Related
    ENSP00000338990.4, ENST00000336854.8
    Conserved Domains (1) summary
    pfam07855
    Location:9172
    ATG101; Autophagy-related protein 101

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000012.12 Reference GRCh38.p13 Primary Assembly

    Range
    52069923..52077495
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_024449120.1XP_024304888.1  autophagy-related protein 101 isoform X1

    Conserved Domains (1) summary
    pfam07855
    Location:9172
    ATG101; Autophagy-related protein 101
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