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Gpd1 glycerol-3-phosphate dehydrogenase 1 [ Rattus norvegicus (Norway rat) ]

Gene ID: 60666, updated on 18-Apr-2019

Summary

Official Symbol
Gpd1provided by RGD
Official Full Name
glycerol-3-phosphate dehydrogenase 1provided by RGD
Primary source
RGD:621381
See related
Ensembl:ENSRNOG00000056457
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
GPDH; Gpd3
Summary
a mitochondrial glycerol 3-phosphate dehydrogenase active in testis [RGD, Feb 2006]
Expression
Biased expression in Muscle (RPKM 2232.8), Thymus (RPKM 2059.3) and 6 other tissues See more
Orthologs

Genomic context

See Gpd1 in Genome Data Viewer
Location:
7q36
Exon count:
9
Annotation release Status Assembly Chr Location
106 current Rnor_6.0 (GCF_000001895.5) 7 NC_005106.4 (141368928..141377931)
104 previous assembly Rnor_5.0 (GCF_000001895.4) X NC_005120.3 (115874138..115882579)

Chromosome 7 - NC_005106.4Genomic Context describing neighboring genes Neighboring gene acid sensing ion channel subunit 1 Neighboring gene uncharacterized LOC108351553 Neighboring gene SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1 Neighboring gene cytochrome c oxidase assembly factor COX14 Neighboring gene ceramide synthase 5

Genomic regions, transcripts, and products

Expression

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Pathways from BioSystems

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • MGC93453

Gene Ontology Provided by RGD

Process Evidence Code Pubs
NADH metabolic process IDA
Inferred from Direct Assay
more info
PubMed 
NADH oxidation IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
NADH oxidation IDA
Inferred from Direct Assay
more info
PubMed 
NADH oxidation ISO
Inferred from Sequence Orthology
more info
PubMed 
carbohydrate metabolic process IDA
Inferred from Direct Assay
more info
PubMed 
cellular response to cAMP IEA
Inferred from Electronic Annotation
more info
 
cellular response to cAMP ISO
Inferred from Sequence Orthology
more info
PubMed 
cellular response to tumor necrosis factor IEA
Inferred from Electronic Annotation
more info
 
cellular response to tumor necrosis factor ISO
Inferred from Sequence Orthology
more info
PubMed 
gluconeogenesis IEA
Inferred from Electronic Annotation
more info
 
gluconeogenesis ISO
Inferred from Sequence Orthology
more info
PubMed 
glycerol-3-phosphate catabolic process IEA
Inferred from Electronic Annotation
more info
 
glycerol-3-phosphate metabolic process IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
glycerol-3-phosphate metabolic process IDA
Inferred from Direct Assay
more info
PubMed 
glycerol-3-phosphate metabolic process ISO
Inferred from Sequence Orthology
more info
PubMed 
glycerolipid metabolic process IDA
Inferred from Direct Assay
more info
PubMed 
glycerophosphate shuttle IEA
Inferred from Electronic Annotation
more info
 
glycerophosphate shuttle ISO
Inferred from Sequence Orthology
more info
PubMed 
positive regulation of glycolytic process IEA
Inferred from Electronic Annotation
more info
 
positive regulation of glycolytic process ISO
Inferred from Sequence Orthology
more info
PubMed 
Component Evidence Code Pubs
cytosol IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
cytosol IDA
Inferred from Direct Assay
more info
PubMed 
glycerol-3-phosphate dehydrogenase complex IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
glycerol-3-phosphate dehydrogenase [NAD(+)], cytoplasmic
Names
GPD-C
GPDH-C
glycerol 3-phosphate dehydrogenase
glycerol-3-phosphate dehydrogenase 1 (soluble)
glycerol-3-phosphate dehydrogenase [NAD+], cytoplasmic
NP_071551.2
XP_006257438.1

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_022215.2NP_071551.2  glycerol-3-phosphate dehydrogenase [NAD(+)], cytoplasmic

    See identical proteins and their annotated locations for NP_071551.2

    Status: PROVISIONAL

    Source sequence(s)
    BC088396
    UniProtKB/Swiss-Prot
    O35077
    Related
    ENSRNOP00000074647.1, ENSRNOT00000087662.1
    Conserved Domains (3) summary
    TIGR03376
    Location:5342
    glycerol3P_DH; glycerol-3-phosphate dehydrogenase (NAD(+))
    pfam01210
    Location:5172
    NAD_Gly3P_dh_N; NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus
    pfam07479
    Location:194335
    NAD_Gly3P_dh_C; NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus

RefSeqs of Annotated Genomes: Rattus norvegicus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Rnor_6.0 Primary Assembly

Genomic

  1. NC_005106.4 Reference Rnor_6.0 Primary Assembly

    Range
    141368928..141377931
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006257376.2XP_006257438.1  glycerol-3-phosphate dehydrogenase [NAD(+)], cytoplasmic isoform X1

    See identical proteins and their annotated locations for XP_006257438.1

    UniProtKB/Swiss-Prot
    O35077
    Conserved Domains (3) summary
    TIGR03376
    Location:5342
    glycerol3P_DH; glycerol-3-phosphate dehydrogenase (NAD(+))
    pfam01210
    Location:5172
    NAD_Gly3P_dh_N; NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus
    pfam07479
    Location:194335
    NAD_Gly3P_dh_C; NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus

Alternate Rn_Celera

Genomic

  1. AC_000075.1 Alternate Rn_Celera

    Range
    127325535..127332926
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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