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Prap1 proline-rich acidic protein 1 [ Rattus norvegicus (Norway rat) ]

Gene ID: 60574, updated on 22-Aug-2021

Summary

Official Symbol
Prap1provided by RGD
Official Full Name
proline-rich acidic protein 1provided by RGD
Primary source
RGD:61876
See related
Ensembl:ENSRNOG00000018446
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
Upa
Summary
specifically expressed in intestine and uterus; may play a role in pregnant uterus, and in digestion and absorption of nutrients in the gastrointestinal tract [RGD, Feb 2006]
Expression
Biased expression in Liver (RPKM 10.7), Testes (RPKM 10.5) and 3 other tissues See more
Orthologs
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Genomic context

See Prap1 in Genome Data Viewer
Location:
1q41
Exon count:
5
Annotation release Status Assembly Chr Location
108 current mRatBN7.2 (GCF_015227675.2) 1 NC_051336.1 (194883078..194886874)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 1 NC_005100.4 (212558257..212562053)

Chromosome 1 - NC_051336.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC102551319 Neighboring gene calcyon neuron-specific vesicular protein Neighboring gene fucose mutarotase Neighboring gene enoyl-CoA hydratase, short chain 1 Neighboring gene polyamine oxidase

Genomic regions, transcripts, and products

Expression

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

General gene information

Homology

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables triglyceride binding ISO
Inferred from Sequence Orthology
more info
 
enables triglyceride binding ISS
Inferred from Sequence or Structural Similarity
more info
 
Process Evidence Code Pubs
involved_in DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest ISO
Inferred from Sequence Orthology
more info
 
involved_in DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest ISS
Inferred from Sequence or Structural Similarity
more info
 
involved_in cellular response to DNA damage stimulus ISO
Inferred from Sequence Orthology
more info
 
involved_in cellular response to DNA damage stimulus ISS
Inferred from Sequence or Structural Similarity
more info
 
involved_in cellular response to X-ray ISO
Inferred from Sequence Orthology
more info
 
involved_in cellular response to X-ray ISS
Inferred from Sequence or Structural Similarity
more info
 
involved_in deactivation of mitotic spindle assembly checkpoint ISO
Inferred from Sequence Orthology
more info
 
involved_in deactivation of mitotic spindle assembly checkpoint ISS
Inferred from Sequence or Structural Similarity
more info
 
involved_in negative regulation of apoptotic process ISO
Inferred from Sequence Orthology
more info
 
involved_in negative regulation of apoptotic process ISS
Inferred from Sequence or Structural Similarity
more info
 
involved_in positive regulation of intestinal lipid absorption ISO
Inferred from Sequence Orthology
more info
 
involved_in positive regulation of intestinal lipid absorption ISS
Inferred from Sequence or Structural Similarity
more info
 
involved_in positive regulation of phospholipid transport ISO
Inferred from Sequence Orthology
more info
 
involved_in positive regulation of phospholipid transport ISS
Inferred from Sequence or Structural Similarity
more info
 
involved_in positive regulation of triglyceride transport ISO
Inferred from Sequence Orthology
more info
 
involved_in positive regulation of triglyceride transport ISS
Inferred from Sequence or Structural Similarity
more info
 
Component Evidence Code Pubs
located_in endoplasmic reticulum ISO
Inferred from Sequence Orthology
more info
 
located_in endoplasmic reticulum ISS
Inferred from Sequence or Structural Similarity
more info
 
located_in extracellular region ISO
Inferred from Sequence Orthology
more info
 
located_in extracellular region ISS
Inferred from Sequence or Structural Similarity
more info
 

General protein information

Preferred Names
proline-rich acidic protein 1
Names
uterine-specific proline-rich acidic protein

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_031669.1NP_113857.1  proline-rich acidic protein 1 precursor

    See identical proteins and their annotated locations for NP_113857.1

    Status: PROVISIONAL

    Source sequence(s)
    AF214733
    UniProtKB/Swiss-Prot
    Q9ES75
    Related
    ENSRNOP00000024912.3, ENSRNOT00000024912.4
    Conserved Domains (1) summary
    pfam15314
    Location:100144
    PRAP; Proline-rich acidic protein 1, pregnancy-specific uterine

RefSeqs of Annotated Genomes: Rattus norvegicus Annotation Release 108 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference mRatBN7.2 Primary Assembly

Genomic

  1. NC_051336.1 Reference mRatBN7.2 Primary Assembly

    Range
    194883078..194886874
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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