U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Stx6 syntaxin 6 [ Rattus norvegicus (Norway rat) ]

Gene ID: 60562, updated on 8-Dec-2022

Summary

Official Symbol
Stx6provided by RGD
Official Full Name
syntaxin 6provided by RGD
Primary source
RGD:61915
See related
Ensembl:ENSRNOG00000003402 AllianceGenome:RGD:61915
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary
Predicted to enable SNAP receptor activity and syntaxin binding activity. Involved in synaptic vesicle to endosome fusion. Located in synaptic vesicle and trans-Golgi network membrane. Is integral component of membrane. Is integral component of synaptic vesicle membrane. Orthologous to human STX6 (syntaxin 6). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in Brain (RPKM 184.0), Thymus (RPKM 159.4) and 9 other tissues See more
Orthologs
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

See Stx6 in Genome Data Viewer
Location:
13q21
Exon count:
8
Annotation release Status Assembly Chr Location
108 current mRatBN7.2 (GCF_015227675.2) 13 NC_051348.1 (67332329..67378580)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 13 NC_005112.4 (72804218..72850757)

Chromosome 13 - NC_051348.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC108352557 Neighboring gene major histocompatibility complex, class I-related Neighboring gene similar to 6820428L09 protein Neighboring gene xenotropic and polytropic retrovirus receptor 1

Genomic regions, transcripts, and products

Expression

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • MGC93348

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables SNAP receptor activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables SNAP receptor activity IEA
Inferred from Electronic Annotation
more info
 
enables SNARE binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
enables syntaxin binding ISO
Inferred from Sequence Orthology
more info
 
Process Evidence Code Pubs
involved_in Golgi ribbon formation ISO
Inferred from Sequence Orthology
more info
 
involved_in Golgi vesicle transport IEA
Inferred from Electronic Annotation
more info
 
involved_in endocytic recycling IDA
Inferred from Direct Assay
more info
PubMed 
acts_upstream_of_or_within endocytic recycling ISO
Inferred from Sequence Orthology
more info
 
involved_in endocytic recycling ISO
Inferred from Sequence Orthology
more info
 
acts_upstream_of_or_within endosome organization ISO
Inferred from Sequence Orthology
more info
 
involved_in intracellular protein transport IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in intracellular protein transport IEA
Inferred from Electronic Annotation
more info
 
involved_in membrane fusion IEA
Inferred from Electronic Annotation
more info
 
involved_in regulation of protein localization ISO
Inferred from Sequence Orthology
more info
 
involved_in retrograde transport, endosome to Golgi IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in retrograde transport, endosome to Golgi IDA
Inferred from Direct Assay
more info
PubMed 
involved_in retrograde transport, endosome to Golgi ISO
Inferred from Sequence Orthology
more info
 
involved_in synaptic vesicle to endosome fusion IDA
Inferred from Direct Assay
more info
PubMed 
involved_in synaptic vesicle to endosome fusion IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in vesicle docking IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in vesicle fusion IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in vesicle fusion ISO
Inferred from Sequence Orthology
more info
 
involved_in vesicle-mediated transport IDA
Inferred from Direct Assay
more info
PubMed 
Component Evidence Code Pubs
located_in Golgi apparatus IDA
Inferred from Direct Assay
more info
PubMed 
located_in Golgi apparatus ISO
Inferred from Sequence Orthology
more info
 
located_in Golgi membrane IEA
Inferred from Electronic Annotation
more info
 
part_of SNARE complex IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
part_of SNARE complex ISO
Inferred from Sequence Orthology
more info
 
located_in cytosol IEA
Inferred from Electronic Annotation
more info
 
located_in cytosol ISO
Inferred from Sequence Orthology
more info
 
located_in early endosome ISO
Inferred from Sequence Orthology
more info
 
is_active_in endomembrane system IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in membrane IDA
Inferred from Direct Assay
more info
PubMed 
located_in membrane ISO
Inferred from Sequence Orthology
more info
 
located_in nucleoplasm IEA
Inferred from Electronic Annotation
more info
 
located_in nucleoplasm ISO
Inferred from Sequence Orthology
more info
 
located_in perinuclear region of cytoplasm ISO
Inferred from Sequence Orthology
more info
 
located_in phagocytic vesicle ISO
Inferred from Sequence Orthology
more info
 
located_in recycling endosome IDA
Inferred from Direct Assay
more info
PubMed 
located_in recycling endosome membrane IEA
Inferred from Electronic Annotation
more info
 
located_in synaptic vesicle IDA
Inferred from Direct Assay
more info
PubMed 
is_active_in synaptic vesicle membrane EXP
Inferred from Experiment
more info
PubMed 
is_active_in synaptic vesicle membrane IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
is_active_in synaptic vesicle membrane IDA
Inferred from Direct Assay
more info
PubMed 
located_in synaptic vesicle membrane IDA
Inferred from Direct Assay
more info
PubMed 
located_in terminal bouton HDA PubMed 
located_in trans-Golgi network IEA
Inferred from Electronic Annotation
more info
 
located_in trans-Golgi network ISO
Inferred from Sequence Orthology
more info
 
located_in trans-Golgi network membrane IDA
Inferred from Direct Assay
more info
PubMed 
located_in trans-Golgi network membrane ISO
Inferred from Sequence Orthology
more info
 

NCBI Reference Sequences (RefSeq)

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_031665.2NP_113853.1  syntaxin-6

    See identical proteins and their annotated locations for NP_113853.1

    Status: PROVISIONAL

    Source sequence(s)
    BC081769
    UniProtKB/Swiss-Prot
    Q63635
    Related
    ENSRNOP00000080858.1, ENSRNOT00000099649.1
    Conserved Domains (2) summary
    cd15851
    Location:166231
    SNARE_Syntaxin6; SNARE motif of syntaxin 6
    cd21447
    Location:5107
    SNARE_NTD_STX6; N-terminal domain of syntaxin-6

RefSeqs of Annotated Genomes: Rattus norvegicus Annotation Release 108 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference mRatBN7.2 Primary Assembly

Genomic

  1. NC_051348.1 Reference mRatBN7.2 Primary Assembly

    Range
    67332329..67378580
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)