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AVPI1 arginine vasopressin induced 1 [ Homo sapiens (human) ]

Gene ID: 60370, updated on 5-Aug-2026
Official Symbol
AVPI1provided by HGNC
Official Full Name
arginine vasopressin induced 1provided by HGNC
Primary source
HGNC:HGNC:30898
See related
Ensembl:ENSG00000119986 MIM:618537; AllianceGenome:HGNC:30898
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
VIP32; VIT32; PP5395
Summary
Predicted to be involved in positive regulation of MAPK cascade. [provided by Alliance of Genome Resources, Jul 2025]
Expression
Ubiquitous expression in adrenal (RPKM 14.7), colon (RPKM 12.7) and 25 other tissues See more
Orthologs
all
Try the new Gene page
Try the new Transcripts and proteins table
See AVPI1 in Genome Data Viewer
Location:
10q24.2
Exon count:
3
Annotation release Status Assembly Chr Location
RS_2025_08 current GRCh38.p14 (GCF_000001405.40) 10 NC_000010.11 (97677424..97687241, complement)
RS_2025_08 current T2T-CHM13v2.0 (GCF_009914755.1) 10 NC_060934.1 (98557625..98567393, complement)
RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 10 NC_000010.10 (99437181..99446998, complement)

Chromosome 10 - NC_000010.11Genomic Context describing neighboring genes Neighboring gene MORN repeat containing 4 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 3854 Neighboring gene ReSE screen-validated silencer GRCh37_chr10:99399170-99399353 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 2683 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 3855 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 3856 Neighboring gene MED14-independent group 3 enhancer GRCh37_chr10:99411103-99412302 Neighboring gene phosphatidylinositol 4-kinase type 2 alpha Neighboring gene H3K27ac hESC enhancer GRCh37_chr10:99435535-99436034 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 3857 Neighboring gene BRD4-independent group 4 enhancer GRCh37_chr10:99446822-99448021 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 3858 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 2685 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr10:99478816-99479636 Neighboring gene MARVEL domain containing 1 Neighboring gene Sharpr-MPRA regulatory region 11334 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 3859 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 2686 Neighboring gene zinc finger FYVE-type containing 27 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 2687 Neighboring gene H3K27ac hESC enhancer GRCh37_chr10:99519797-99520296

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. AVP-induced VIT32 gene expression in collecting duct cells occurs via trans-activation of a CRE in the 5'-flanking region of the VIT32 gene. Thomas CP, et al. Am J Physiol Renal Physiol, 2004 Sep. PMID 15140762
  2. A novel vasopressin-induced transcript promotes MAP kinase activation and ENaC downregulation. Nicod M, et al. EMBO J, 2002 Oct 1. PMID 12356727, Free PMC Article
  3. Anisomelic acid promotes proteasomal degradation of HPV16 E6 via E3 ligase recruitment: A mass spectrometry-based interactome study. Santos Silva M, et al. J Proteomics, 2026 Jan 6. PMID 40967472
  4. Expanding the substantial interactome of NEMO using protein microarrays. Fenner BJ, et al. PLoS One, 2010 Jan 20. PMID 20098747, Free PMC Article
  5. Large-scale cDNA transfection screening for genes related to cancer development and progression. Wan D, et al. Proc Natl Acad Sci U S A, 2004 Nov 2. PMID 15498874, Free PMC Article

See all (23) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Observational study of gene-disease association. (HuGE Navigator)
    Title: A scan of chromosome 10 identifies a novel locus showing strong association with late-onset Alzheimer disease.
Submit: New GeneRIF Correction

Find tests for this gene in the NIH Genetic Testing Registry (GTR)

Review eQTL and phenotype association data in this region using PheGenI

See variants in ClinVar

See studies and variants in dbVar

See Variation Viewer (GRCh37.p13)

Products Interactant Other Gene Complex Source Pubs Description

Markers

Homology

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
Process Evidence Code Pubs
involved_in positive regulation of MAPK cascade IBA
Inferred from Biological aspect of Ancestor
more info
  
Preferred Names
arginine vasopressin-induced protein 1
Names
AVP-induced protein 1
vasopressin-induced transcript

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_021732.3 → NP_068378.2  arginine vasopressin-induced protein 1

    Status: VALIDATED

    Source sequence(s)
    AL355315
    Consensus CDS
    CCDS7470.1
    UniProtKB/Swiss-Prot
    Q53G32, Q5T686, Q9H2R9, Q9HBN9
    Related
    ENSP00000359660.3, ENST00000370626.4
    Conserved Domains (1) summary
    pfam15063
    Location:2 → 70
    TC1; Thyroid cancer protein 1

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2025_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000010.11 Reference GRCh38.p14 Primary Assembly

    Range
    97677424..97687241 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_017016494.2 → XP_016871983.1  arginine vasopressin-induced protein 1 isoform X1

    UniProtKB/Swiss-Prot
    Q53G32, Q5T686, Q9H2R9, Q9HBN9
    Related
    ENSP00000564665.1, ENST00000894606.1
    Conserved Domains (1) summary
    pfam15063
    Location:2 → 70
    TC1; Thyroid cancer protein 1

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060934.1 Alternate T2T-CHM13v2.0

    Range
    98557625..98567393 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_054366513.1 → XP_054222488.1  arginine vasopressin-induced protein 1 isoform X1

    UniProtKB/Swiss-Prot
    Q53G32, Q5T686, Q9H2R9, Q9HBN9
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q5T686.3 GenPept UniProtKB/Swiss-Prot:Q5T686

Gene LinkOut

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