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Donson downstream neighbor of SON [ Mus musculus (house mouse) ]

Gene ID: 60364, updated on 5-Mar-2024

Summary

Official Symbol
Donsonprovided by MGI
Official Full Name
downstream neighbor of SONprovided by MGI
Primary source
MGI:MGI:1890621
See related
Ensembl:ENSMUSG00000022960 AllianceGenome:MGI:1890621
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
ORF60; 1110025J21Rik
Summary
Predicted to be involved in mitotic G2 DNA damage checkpoint signaling; nuclear DNA replication; and replication fork protection. Predicted to be located in replication fork. Predicted to be part of replisome. Predicted to be active in nucleus. Is expressed in several structures, including central nervous system; genitourinary system; gut; limb; and sensory organ. Orthologous to human DONSON (DNA replication fork stabilization factor DONSON). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in testis adult (RPKM 13.4), liver E14 (RPKM 10.6) and 27 other tissues See more
Orthologs
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Genomic context

See Donson in Genome Data Viewer
Location:
16 C3.3- C4; 16 53.25 cM
Exon count:
11
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 16 NC_000082.7 (91463744..91485702, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 16 NC_000082.6 (91666856..91688932, complement)

Chromosome 16 - NC_000082.7Genomic Context describing neighboring genes Neighboring gene phosphoribosylglycinamide formyltransferase Neighboring gene STARR-positive B cell enhancer ABC_E3174 Neighboring gene STARR-positive B cell enhancer ABC_E7475 Neighboring gene predicted gene, 36712 Neighboring gene Son DNA binding protein Neighboring gene STARR-positive B cell enhancer ABC_E2468 Neighboring gene predicted gene 10785 Neighboring gene crystallin zeta like 1 Neighboring gene predicted gene, 46543

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)

General gene information

Markers

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
 
Process Evidence Code Pubs
involved_in DNA damage checkpoint signaling ISO
Inferred from Sequence Orthology
more info
 
involved_in DNA replication ISO
Inferred from Sequence Orthology
more info
 
involved_in mitotic DNA replication checkpoint signaling ISO
Inferred from Sequence Orthology
more info
 
involved_in mitotic G2 DNA damage checkpoint signaling ISO
Inferred from Sequence Orthology
more info
 
acts_upstream_of_or_within multicellular organism development IEA
Inferred from Electronic Annotation
more info
 
involved_in nuclear DNA replication IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in replication fork processing ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in nucleus ISO
Inferred from Sequence Orthology
more info
 
located_in replication fork ISO
Inferred from Sequence Orthology
more info
 
part_of replisome ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
protein downstream neighbor of Son
Names
protein 3SG

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_021720.1NP_068366.1  protein downstream neighbor of Son

    See identical proteins and their annotated locations for NP_068366.1

    Status: PROVISIONAL

    Source sequence(s)
    BC043316
    Consensus CDS
    CCDS28330.1
    UniProtKB/Swiss-Prot
    Q80V93, Q8BV55, Q9QXP4
    UniProtKB/TrEMBL
    F6QFE2
    Related
    ENSMUSP00000023682.5, ENSMUST00000023682.12

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000082.7 Reference GRCm39 C57BL/6J

    Range
    91463744..91485702 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006523069.5XP_006523132.1  protein downstream neighbor of Son isoform X1

    See identical proteins and their annotated locations for XP_006523132.1

    UniProtKB/Swiss-Prot
    Q80V93, Q8BV55, Q9QXP4
    UniProtKB/TrEMBL
    F6QFE2