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PRDM13 PR/SET domain 13 [ Homo sapiens (human) ]

Gene ID: 59336, updated on 8-Dec-2018

Summary

Official Symbol
PRDM13provided by HGNC
Official Full Name
PR/SET domain 13provided by HGNC
Primary source
HGNC:HGNC:13998
See related
Ensembl:ENSG00000112238 MIM:616741
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
PFM10; MU-MB-20.220
Expression
Low expression observed in reference dataset See more
Orthologs

Genomic context

See PRDM13 in Genome Data Viewer
Location:
6q16.2
Exon count:
4
Annotation release Status Assembly Chr Location
109 current GRCh38.p12 (GCF_000001405.38) 6 NC_000006.12 (99606774..99615578)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 6 NC_000006.11 (100054650..100063454)

Chromosome 6 - NC_000006.12Genomic Context describing neighboring genes Neighboring gene thiosulfate sulfurtransferase like domain containing 3 Neighboring gene CCNC and PRDM13 intergenic region DNase I hypersensitve site DHS6S1 Neighboring gene ribosomal protein S3 pseudogene 5 Neighboring gene melanin concentrating hormone receptor 2 Neighboring gene MCHR2 antisense RNA 1 Neighboring gene nucleophosmin 1 pseudogene 38

Genomic regions, transcripts, and products

Bibliography

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Phenotypes

NHGRI GWAS Catalog

Description
Thirty new loci for age at menarche identified by a meta-analysis of genome-wide association studies.
NHGRI GWA Catalog

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by GOA

Function Evidence Code Pubs
DNA-binding transcription factor activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
DNA-binding transcription factor activity, RNA polymerase II-specific ISA
Inferred from Sequence Alignment
more info
 
RNA polymerase II regulatory region sequence-specific DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
chromatin DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
histone methyltransferase activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
metal ion binding IEA
Inferred from Electronic Annotation
more info
 
sequence-specific DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Process Evidence Code Pubs
histone methylation IEA
Inferred from Electronic Annotation
more info
 
negative regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
neurogenesis IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
nucleus IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 

General protein information

Preferred Names
PR domain zinc finger protein 13
Names
PR domain 13
PR domain containing 13
PR-domain containing protein 13

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_021620.3NP_067633.2  PR domain zinc finger protein 13

    See identical proteins and their annotated locations for NP_067633.2

    Status: VALIDATED

    Source sequence(s)
    AL035087, AY004253
    Consensus CDS
    CCDS43487.1
    UniProtKB/Swiss-Prot
    Q9H4Q3
    Related
    ENSP00000358217.4, ENST00000369215.4
    Conserved Domains (6) summary
    sd00017
    Location:575595
    ZF_C2H2; C2H2 Zn finger [structural motif]
    sd00018
    Location:137160
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam00096
    Location:575595
    zf-C2H2; Zinc finger, C2H2 type
    pfam00856
    Location:14111
    SET; SET domain
    pfam13465
    Location:588610
    zf-H2C2_2; Zinc-finger double domain
    pfam13894
    Location:630653
    zf-C2H2_4; C2H2-type zinc finger

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p12 Primary Assembly

Genomic

  1. NC_000006.12 Reference GRCh38.p12 Primary Assembly

    Range
    99606774..99615578
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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