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Mettl9 methyltransferase like 9 [ Mus musculus (house mouse) ]

Gene ID: 59052, updated on 6-Jun-2024

Summary

Official Symbol
Mettl9provided by MGI
Official Full Name
methyltransferase like 9provided by MGI
Primary source
MGI:MGI:1914862
See related
Ensembl:ENSMUSG00000030876 AllianceGenome:MGI:1914862
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Drev; mMETTL9; MNCb-5680; 0610012D09Rik
Summary
Enables protein-L-histidine N-pros-methyltransferase activity. Predicted to act upstream of or within methylation. Predicted to be located in mitochondrion. Predicted to be active in endoplasmic reticulum. Is expressed in retina inner nuclear layer and retina outer nuclear layer. Orthologous to human METTL9 (methyltransferase like 9). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in CNS E11.5 (RPKM 36.9), CNS E14 (RPKM 28.6) and 28 other tissues See more
Orthologs
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Genomic context

See Mettl9 in Genome Data Viewer
Location:
7 F2; 7 65.07 cM
Exon count:
12
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 7 NC_000073.7 (120631717..120676058)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 7 NC_000073.6 (121032384..121076835)

Chromosome 7 - NC_000073.7Genomic Context describing neighboring genes Neighboring gene major facilitator superfamily domain containing 13B Neighboring gene STARR-positive B cell enhancer ABC_E4973 Neighboring gene predicted pseudogene 9234 Neighboring gene predicted gene, 25924 Neighboring gene predicted gene, 27991 Neighboring gene 60S ribosomal protein L32 pseudogene Neighboring gene immunoglobulin superfamily, member 6 Neighboring gene otoancorin Neighboring gene STARR-seq mESC enhancer starr_20059 Neighboring gene src family associated phosphoprotein 2 pseudogene

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables methyltransferase activity IEA
Inferred from Electronic Annotation
more info
 
enables protein-L-histidine N-pros-methyltransferase activity IDA
Inferred from Direct Assay
more info
PubMed 
enables protein-L-histidine N-pros-methyltransferase activity ISO
Inferred from Sequence Orthology
more info
 
enables transferase activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
acts_upstream_of_or_within methylation IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
is_active_in endoplasmic reticulum ISO
Inferred from Sequence Orthology
more info
 
located_in mitochondrion IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
protein-L-histidine N-pros-methyltransferase
Names
DORA reverse strand protein
methyltransferase-like protein 9
NP_001405493.1
NP_001405494.1
NP_001405495.1
NP_001405496.1
NP_001405497.1
NP_001405498.1
NP_001405499.1
NP_001405500.1
NP_001405501.1
NP_001405502.1
NP_001405503.1
NP_001405504.1
NP_001405505.1
NP_001405506.1
NP_001405507.1
NP_001405508.1
NP_001405509.1
NP_001405510.1
NP_001405511.1
NP_001405512.1
NP_067529.2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001418564.1NP_001405493.1  protein-L-histidine N-pros-methyltransferase isoform 2 precursor

    Status: VALIDATED

    Source sequence(s)
    AC140782
  2. NM_001418565.1NP_001405494.1  protein-L-histidine N-pros-methyltransferase isoform 3

    Status: VALIDATED

    Source sequence(s)
    AC140782
  3. NM_001418566.1NP_001405495.1  protein-L-histidine N-pros-methyltransferase isoform 4

    Status: VALIDATED

    Source sequence(s)
    AC140782
  4. NM_001418567.1NP_001405496.1  protein-L-histidine N-pros-methyltransferase isoform 5

    Status: VALIDATED

    Source sequence(s)
    AC140782
    UniProtKB/TrEMBL
    A0A140LJ45
  5. NM_001418568.1NP_001405497.1  protein-L-histidine N-pros-methyltransferase isoform 6 precursor

    Status: VALIDATED

    Source sequence(s)
    AC140782
  6. NM_001418569.1NP_001405498.1  protein-L-histidine N-pros-methyltransferase isoform 7

    Status: VALIDATED

    Source sequence(s)
    AC140782
  7. NM_001418570.1NP_001405499.1  protein-L-histidine N-pros-methyltransferase isoform 8

    Status: VALIDATED

    Source sequence(s)
    AC140782
  8. NM_001418571.1NP_001405500.1  protein-L-histidine N-pros-methyltransferase isoform 9

    Status: VALIDATED

    Source sequence(s)
    AC140782
    UniProtKB/TrEMBL
    A0A140LJ45
  9. NM_001418572.1NP_001405501.1  protein-L-histidine N-pros-methyltransferase isoform 10 precursor

    Status: VALIDATED

    Source sequence(s)
    AC140782
  10. NM_001418573.1NP_001405502.1  protein-L-histidine N-pros-methyltransferase isoform 11 precursor

    Status: VALIDATED

    Source sequence(s)
    AC140782
  11. NM_001418574.1NP_001405503.1  protein-L-histidine N-pros-methyltransferase isoform 5

    Status: VALIDATED

    Source sequence(s)
    AC140782
    UniProtKB/TrEMBL
    A0A140LJ45
  12. NM_001418575.1NP_001405504.1  protein-L-histidine N-pros-methyltransferase isoform 9

    Status: VALIDATED

    Source sequence(s)
    AC140782
    UniProtKB/TrEMBL
    A0A140LJ45
  13. NM_001418576.1NP_001405505.1  protein-L-histidine N-pros-methyltransferase isoform 5

    Status: VALIDATED

    Source sequence(s)
    AC140782
    UniProtKB/TrEMBL
    A0A140LJ45
    Related
    ENSMUSP00000147071.2, ENSMUST00000207351.2
  14. NM_001418577.1NP_001405506.1  protein-L-histidine N-pros-methyltransferase isoform 9

    Status: VALIDATED

    Source sequence(s)
    AC140782
    UniProtKB/TrEMBL
    A0A140LJ45
  15. NM_001418578.1NP_001405507.1  protein-L-histidine N-pros-methyltransferase isoform 5

    Status: VALIDATED

    Source sequence(s)
    AC140782
    UniProtKB/TrEMBL
    A0A140LJ45
  16. NM_001418579.1NP_001405508.1  protein-L-histidine N-pros-methyltransferase isoform 9

    Status: VALIDATED

    Source sequence(s)
    AC140782
    UniProtKB/TrEMBL
    A0A140LJ45
  17. NM_001418580.1NP_001405509.1  protein-L-histidine N-pros-methyltransferase isoform 12

    Status: VALIDATED

    Source sequence(s)
    AC140782
  18. NM_001418581.1NP_001405510.1  protein-L-histidine N-pros-methyltransferase isoform 13

    Status: VALIDATED

    Source sequence(s)
    AC140782
  19. NM_001418582.1NP_001405511.1  protein-L-histidine N-pros-methyltransferase isoform 14

    Status: VALIDATED

    Source sequence(s)
    AC140782
  20. NM_001418583.1NP_001405512.1  protein-L-histidine N-pros-methyltransferase isoform 15

    Status: VALIDATED

    Source sequence(s)
    AC140782
  21. NM_021554.3NP_067529.2  protein-L-histidine N-pros-methyltransferase isoform 1 precursor

    See identical proteins and their annotated locations for NP_067529.2

    Status: VALIDATED

    Source sequence(s)
    AC140782
    Consensus CDS
    CCDS21800.1
    UniProtKB/Swiss-Prot
    A0JG25, Q3TDX0, Q641L4, Q8R567, Q9EPL3, Q9EPL4, Q9JJ88
    Related
    ENSMUSP00000033163.7, ENSMUST00000033163.8
    Conserved Domains (1) summary
    pfam05219
    Location:56317
    DREV; DREV methyltransferase

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000073.7 Reference GRCm39 C57BL/6J

    Range
    120631717..120676058
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)