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Nsa2 NSA2 ribosome biogenesis homolog [ Mus musculus (house mouse) ]

Gene ID: 59050, updated on 5-Mar-2024

Summary

Official Symbol
Nsa2provided by MGI
Official Full Name
NSA2 ribosome biogenesis homologprovided by MGI
Primary source
MGI:MGI:1913883
See related
Ensembl:ENSMUSG00000060739 AllianceGenome:MGI:1913883
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Yr29; LNR42; Nsa2p; Tinp1; 5730427N09Rik
Summary
Predicted to be involved in maturation of 5.8S rRNA and maturation of LSU-rRNA. Predicted to act upstream of or within rRNA processing. Predicted to be located in nucleus. Predicted to be part of preribosome, large subunit precursor. Is expressed in several structures, including branchial arch; extraembryonic ectoderm; neural ectoderm; and trunk mesenchyme. Orthologous to human NSA2 (NSA2 ribosome biogenesis factor). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Broad expression in CNS E11.5 (RPKM 31.3), bladder adult (RPKM 26.9) and 24 other tissues See more
Orthologs
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Genomic context

Location:
13 D1; 13 50.66 cM
Exon count:
6
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 13 NC_000079.7 (97265935..97274434, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 13 NC_000079.6 (97129427..97137926, complement)

Chromosome 13 - NC_000079.7Genomic Context describing neighboring genes Neighboring gene RIKEN cDNA 1700029F12 gene Neighboring gene predicted gene, 41028 Neighboring gene STARR-seq mESC enhancer starr_35359 Neighboring gene family with sequence similarity 169, member A Neighboring gene STARR-seq mESC enhancer starr_35363 Neighboring gene proteolipid protein 2, retrotransposed Neighboring gene STARR-positive B cell enhancer ABC_E3094 Neighboring gene G elongation factor, mitochondrial 2 Neighboring gene hexosaminidase B Neighboring gene STARR-seq mESC enhancer starr_35367 Neighboring gene STARR-seq mESC enhancer starr_35370 Neighboring gene ectodermal-neural cortex 1

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (1) 

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Clone Names

  • MGC118054

Gene Ontology Provided by MGI

Process Evidence Code Pubs
involved_in maturation of 5.8S rRNA IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in maturation of LSU-rRNA IBA
Inferred from Biological aspect of Ancestor
more info
 
acts_upstream_of_or_within rRNA processing IEA
Inferred from Electronic Annotation
more info
 
acts_upstream_of_or_within ribosome biogenesis IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 
part_of preribosome, large subunit precursor IBA
Inferred from Biological aspect of Ancestor
more info
 
part_of ribonucleoprotein complex IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
ribosome biogenesis protein NSA2 homolog
Names
L-name related protein
L-name-related protein 42
TGF-beta-inducible nuclear protein 1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_021552.5NP_067527.3  ribosome biogenesis protein NSA2 homolog

    See identical proteins and their annotated locations for NP_067527.3

    Status: VALIDATED

    Source sequence(s)
    AC154620, AK078457, CJ132894
    Consensus CDS
    CCDS36756.1
    UniProtKB/Swiss-Prot
    A0JNU8, Q8BHQ6, Q8BHT0, Q9CR47, Q9CRQ0, Q9CS34, Q9CYK0, Q9JKF9
    UniProtKB/TrEMBL
    Q5M9P2
    Related
    ENSMUSP00000073161.8, ENSMUST00000073456.9
    Conserved Domains (1) summary
    cd11381
    Location:4260
    NSA2; pre-ribosomal protein NSA2 (Nop seven-associated 2)

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000079.7 Reference GRCm39 C57BL/6J

    Range
    97265935..97274434 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)