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Thap11 THAP domain containing 11 [ Mus musculus (house mouse) ]

Gene ID: 59016, updated on 12-May-2024

Summary

Official Symbol
Thap11provided by MGI
Official Full Name
THAP domain containing 11provided by MGI
Primary source
MGI:MGI:1930964
See related
Ensembl:ENSMUSG00000036442 AllianceGenome:MGI:1930964
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Ronin; CTG-B43a; CTG-B45d; 2810036E22Rik
Summary
Predicted to enable DNA-binding transcription repressor activity, RNA polymerase II-specific; RNA polymerase II cis-regulatory region sequence-specific DNA binding activity; and zinc ion binding activity. Predicted to be involved in negative regulation of transcription by RNA polymerase II. Predicted to be located in cytosol. Predicted to be active in nucleoplasm. Is expressed in 1-cell stage embryo; brain ventricular layer; forelimb bud; inferior colliculus; and oocyte. Orthologous to human THAP11 (THAP domain containing 11). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
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Genomic context

See Thap11 in Genome Data Viewer
Location:
8 D3; 8 53.05 cM
Exon count:
1
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 8 NC_000074.7 (106581735..106583582)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 8 NC_000074.6 (105855103..105856950)

Chromosome 8 - NC_000074.7Genomic Context describing neighboring genes Neighboring gene RAN binding protein 10 Neighboring gene STARR-positive B cell enhancer ABC_E2272 Neighboring gene translin-associated factor X (Tsnax) interacting protein 1 Neighboring gene STARR-positive B cell enhancer ABC_E2875 Neighboring gene centromere protein T Neighboring gene STARR-positive B cell enhancer ABC_E3799 Neighboring gene STARR-seq mESC enhancer starr_22544 Neighboring gene nuclear transport factor 2 Neighboring gene STARR-seq mESC enhancer starr_22545 Neighboring gene CapStarr-seq enhancer MGSCv37_chr8:108404648-108404831 Neighboring gene enhancer of mRNA decapping 4

Genomic regions, transcripts, and products

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Gene Ontology Provided by MGI

Component Evidence Code Pubs
part_of RNA polymerase II transcription regulator complex IC
Inferred by Curator
more info
PubMed 
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 
located_in cytosol ISO
Inferred from Sequence Orthology
more info
 
is_active_in nucleoplasm IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in nucleoplasm ISO
Inferred from Sequence Orthology
more info
 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
THAP domain-containing protein 11

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_021513.2NP_067488.1  THAP domain-containing protein 11

    See identical proteins and their annotated locations for NP_067488.1

    Status: VALIDATED

    Source sequence(s)
    AC116569
    Consensus CDS
    CCDS22616.1
    UniProtKB/Swiss-Prot
    Q3TCZ5, Q99KZ0, Q9JJD0
    Related
    ENSMUSP00000048994.8, ENSMUST00000040445.9
    Conserved Domains (1) summary
    pfam05485
    Location:581
    THAP; THAP domain

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000074.7 Reference GRCm39 C57BL/6J

    Range
    106581735..106583582
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)