Format

Send to:

Choose Destination

Hibadh 3-hydroxyisobutyrate dehydrogenase [ Mus musculus (house mouse) ]

Gene ID: 58875, updated on 18-Apr-2019

Summary

Official Symbol
Hibadhprovided by MGI
Official Full Name
3-hydroxyisobutyrate dehydrogenaseprovided by MGI
Primary source
MGI:MGI:1889802
See related
Ensembl:ENSMUSG00000029776
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
AI265272; 6430402H10Rik
Expression
Broad expression in kidney adult (RPKM 114.2), liver adult (RPKM 95.3) and 26 other tissues See more
Orthologs

Genomic context

See Hibadh in Genome Data Viewer
Location:
6; 6 B3
Exon count:
8
Annotation release Status Assembly Chr Location
106 current GRCm38.p4 (GCF_000001635.24) 6 NC_000072.6 (52546230..52640300, complement)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 6 NC_000072.5 (52496224..52590294, complement)

Chromosome 6 - NC_000072.6Genomic Context describing neighboring genes Neighboring gene ribosomal protein L38 pseudogene Neighboring gene RIKEN cDNA 1700094M24 gene Neighboring gene predicted gene, 33047 Neighboring gene Tax1 (human T cell leukemia virus type I) binding protein 1 Neighboring gene JAZF zinc finger 1 Neighboring gene predicted gene, 33219

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Gene trapped (1) 
  • Targeted (2) 

Pathways from BioSystems

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
3-hydroxyisobutyrate dehydrogenase activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
3-hydroxyisobutyrate dehydrogenase activity ISO
Inferred from Sequence Orthology
more info
 
NAD binding IEA
Inferred from Electronic Annotation
more info
 
NADP binding IEA
Inferred from Electronic Annotation
more info
 
oxidoreductase activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
branched-chain amino acid catabolic process IEA
Inferred from Electronic Annotation
more info
 
oxidation-reduction process IEA
Inferred from Electronic Annotation
more info
 
valine catabolic process IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
valine catabolic process ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
mitochondrion HDA PubMed 
mitochondrion IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 

General protein information

Preferred Names
3-hydroxyisobutyrate dehydrogenase, mitochondrial
NP_663542.1

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_145567.1NP_663542.1  3-hydroxyisobutyrate dehydrogenase, mitochondrial precursor

    See identical proteins and their annotated locations for NP_663542.1

    Status: PROVISIONAL

    Source sequence(s)
    BC003914
    Consensus CDS
    CCDS20151.1
    UniProtKB/Swiss-Prot
    Q99L13
    Related
    ENSMUSP00000031788.8, ENSMUST00000031788.8
    Conserved Domains (3) summary
    TIGR01692
    Location:43330
    HIBADH; 3-hydroxyisobutyrate dehydrogenase
    pfam03446
    Location:38199
    NAD_binding_2; NAD binding domain of 6-phosphogluconate dehydrogenase
    pfam14833
    Location:202329
    NAD_binding_11; NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38.p4 C57BL/6J

Genomic

  1. NC_000072.6 Reference GRCm38.p4 C57BL/6J

    Range
    52546230..52640300 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Support Center