Format

Send to:

Choose Destination

RAB3B RAB3B, member RAS oncogene family [ Homo sapiens (human) ]

Gene ID: 5865, updated on 8-Jul-2021

Summary

Official Symbol
RAB3Bprovided by HGNC
Official Full Name
RAB3B, member RAS oncogene familyprovided by HGNC
Primary source
HGNC:HGNC:9778
See related
Ensembl:ENSG00000169213 MIM:179510
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Expression
Biased expression in prostate (RPKM 6.0), brain (RPKM 3.4) and 11 other tissues See more
Orthologs
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

See RAB3B in Genome Data Viewer
Location:
1p32.3
Exon count:
6
Annotation release Status Assembly Chr Location
109.20210514 current GRCh38.p13 (GCF_000001405.39) 1 NC_000001.11 (51907956..51990700, complement)
105.20201022 previous assembly GRCh37.p13 (GCF_000001405.25) 1 NC_000001.10 (52373628..52456372, complement)

Chromosome 1 - NC_000001.11Genomic Context describing neighboring genes Neighboring gene nardilysin convertase Neighboring gene tRNA splicing endonuclease subunit 15 pseudogene 2 Neighboring gene Sharpr-MPRA regulatory region 5937 Neighboring gene RNA, 5S ribosomal pseudogene 48 Neighboring gene ribosomal protein S26 pseudogene 14 Neighboring gene Sharpr-MPRA regulatory region 8174 Neighboring gene RNA, 7SL, cytoplasmic 290, pseudogene

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables GDP binding IDA
Inferred from Direct Assay
more info
PubMed 
enables GTP binding IEA
Inferred from Electronic Annotation
more info
 
enables GTPase activity IDA
Inferred from Direct Assay
more info
PubMed 
enables myosin V binding IPI
Inferred from Physical Interaction
more info
PubMed 
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Component Evidence Code Pubs
located_in Golgi apparatus IEA
Inferred from Electronic Annotation
more info
 
is_active_in anchored component of synaptic vesicle membrane IDA
Inferred from Direct Assay
more info
PubMed 
located_in anchored component of synaptic vesicle membrane IDA
Inferred from Direct Assay
more info
PubMed 
is_active_in anchored component of synaptic vesicle membrane IMP
Inferred from Mutant Phenotype
more info
PubMed 
located_in anchored component of synaptic vesicle membrane IMP
Inferred from Mutant Phenotype
more info
PubMed 
located_in cytoplasm IDA
Inferred from Direct Assay
more info
PubMed 
located_in cytosol IEA
Inferred from Electronic Annotation
more info
 
is_active_in dopaminergic synapse IDA
Inferred from Direct Assay
more info
PubMed 
located_in dopaminergic synapse IDA
Inferred from Direct Assay
more info
PubMed 
is_active_in dopaminergic synapse IMP
Inferred from Mutant Phenotype
more info
PubMed 
located_in dopaminergic synapse IMP
Inferred from Mutant Phenotype
more info
PubMed 
is_active_in endosome IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in extracellular exosome HDA PubMed 
located_in perinuclear region of cytoplasm IDA
Inferred from Direct Assay
more info
PubMed 
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
is_active_in synaptic vesicle IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in vesicle IDA
Inferred from Direct Assay
more info
PubMed 

General protein information

Preferred Names
ras-related protein Rab-3B
Names
brain antigen RAB3B

NCBI Reference Sequences (RefSeq)

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_002867.4NP_002858.2  ras-related protein Rab-3B

    See identical proteins and their annotated locations for NP_002858.2

    Status: VALIDATED

    Source sequence(s)
    AL589663, AU119030, BC005035
    Consensus CDS
    CCDS560.1
    UniProtKB/Swiss-Prot
    P20337
    Related
    ENSP00000360718.3, ENST00000371655.4
    Conserved Domains (2) summary
    smart00175
    Location:23183
    RAB; Rab subfamily of small GTPases
    cd01865
    Location:22186
    Rab3; Rab GTPase family 3 contains Rab3A, Rab3B, Rab3C and Rab3D

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20210514

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000001.11 Reference GRCh38.p13 Primary Assembly

    Range
    51907956..51990700 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_017001958.1XP_016857447.1  ras-related protein Rab-3B isoform X1

    UniProtKB/Swiss-Prot
    P20337
    Conserved Domains (2) summary
    smart00175
    Location:23183
    RAB; Rab subfamily of small GTPases
    cd01865
    Location:22186
    Rab3; Rab GTPase family 3 contains Rab3A, Rab3B, Rab3C and Rab3D
Support Center