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PRM3 protamine 3 [ Homo sapiens (human) ]

Gene ID: 58531, updated on 5-Aug-2022

Summary

Official Symbol
PRM3provided by HGNC
Official Full Name
protamine 3provided by HGNC
Primary source
HGNC:HGNC:13732
See related
Ensembl:ENSG00000178257 AllianceGenome:HGNC:13732
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary
Predicted to enable DNA binding activity. Predicted to be involved in flagellated sperm motility. Predicted to be located in nucleus. Predicted to be part of nucleosome. Predicted to be active in cytoplasm. [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
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Genomic context

See PRM3 in Genome Data Viewer
Location:
16p13.13
Exon count:
1
Annotation release Status Assembly Chr Location
110 current GRCh38.p14 (GCF_000001405.40) 16 NC_000016.10 (11273199..11273629, complement)
110 current T2T-CHM13v2.0 (GCF_009914755.1) 16 NC_060940.1 (11309421..11309851, complement)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 16 NC_000016.9 (11367056..11367486, complement)

Chromosome 16 - NC_000016.10Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC105371082 Neighboring gene suppressor of cytokine signaling 1 Neighboring gene small nucleolar RNA SNORA48 Neighboring gene transition protein 2 Neighboring gene protamine 2

Genomic regions, transcripts, and products

Phenotypes

EBI GWAS Catalog

Description
Genetic variants associated with disordered eating.
EBI GWAS Catalog
Genome-wide meta-analysis identifies novel multiple sclerosis susceptibility loci.
EBI GWAS Catalog
Meta-analysis of genome-wide association study data identifies additional type 1 diabetes risk loci.
EBI GWAS Catalog

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Homology

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables DNA binding IEA
Inferred from Electronic Annotation
more info
 
enables molecular_function ND
No biological Data available
more info
 
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
 
involved_in cell differentiation IEA
Inferred from Electronic Annotation
more info
 
involved_in chromosome condensation IEA
Inferred from Electronic Annotation
more info
 
involved_in flagellated sperm motility IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in spermatogenesis IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
is_active_in cellular_component ND
No biological Data available
more info
 
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
part_of nucleosome IEA
Inferred from Electronic Annotation
more info
 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
protamine-3
Names
gene 4
sperm protamine P3

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_021247.3NP_067070.2  protamine-3

    Status: VALIDATED

    Source sequence(s)
    AC009121, AW666005, KF459690
    Consensus CDS
    CCDS76821.1
    UniProtKB/Swiss-Prot
    Q9NNZ6
    Related
    ENSP00000325638.2, ENST00000327157.4

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 110 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000016.10 Reference GRCh38.p14 Primary Assembly

    Range
    11273199..11273629 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060940.1 Alternate T2T-CHM13v2.0

    Range
    11309421..11309851 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)