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ZNF71 zinc finger protein 71 [ Homo sapiens (human) ]

Gene ID: 58491, updated on 11-Jun-2021

Summary

Official Symbol
ZNF71provided by HGNC
Official Full Name
zinc finger protein 71provided by HGNC
Primary source
HGNC:HGNC:13141
See related
Ensembl:ENSG00000197951 MIM:194545
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
EZFIT
Expression
Ubiquitous expression in endometrium (RPKM 1.6), fat (RPKM 1.6) and 25 other tissues See more
Orthologs
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Genomic context

See ZNF71 in Genome Data Viewer
Location:
19q13.43
Exon count:
4
Annotation release Status Assembly Chr Location
109.20210514 current GRCh38.p13 (GCF_000001405.39) 19 NC_000019.10 (56595302..56624486)
105.20201022 previous assembly GRCh37.p13 (GCF_000001405.25) 19 NC_000019.9 (57106670..57135854)

Chromosome 19 - NC_000019.10Genomic Context describing neighboring genes Neighboring gene zinc finger protein 470 Neighboring gene sialic acid binding Ig like lectin 31, pseudogene Neighboring gene ZNF71-SMIM17 readthrough (NMD candidate) Neighboring gene Sharpr-MPRA regulatory region 15209 Neighboring gene small integral membrane protein 17

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Phenotypes

Associated conditions

Description Tests
A genome-wide association study of total serum and mite-specific IgEs in asthma patients.
GeneReviews: Not available

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables DNA-binding transcription activator activity, RNA polymerase II-specific IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
 
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
involved_in positive regulation of transcription by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
 
involved_in regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 

General protein information

Preferred Names
endothelial zinc finger protein induced by tumor necrosis factor alpha
Names
Kruppel-related zinc finger protein

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001370214.1NP_001357143.1  endothelial zinc finger protein induced by tumor necrosis factor alpha isoform 1

    Status: VALIDATED

    Source sequence(s)
    AA580897, AC007228, AF269249, BC014280, BQ932244, CA416578, CR989498, HY138791
    Conserved Domains (2) summary
    COG5048
    Location:110479
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:272292
    ZF_C2H2; C2H2 Zn finger [structural motif]
  2. NM_001370215.1NP_001357144.1  endothelial zinc finger protein induced by tumor necrosis factor alpha isoform 2

    Status: VALIDATED

    Source sequence(s)
    AA580897, AC007228, AF269249, BC014280, BQ932244, CA416578, CR989498, HY138791
    Related
    ENSP00000471138.2, ENST00000599599.7
    Conserved Domains (3) summary
    COG5048
    Location:170544
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:332352
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam01352
    Location:1354
    KRAB; KRAB box
  3. NM_021216.5NP_067039.1  endothelial zinc finger protein induced by tumor necrosis factor alpha isoform 1

    See identical proteins and their annotated locations for NP_067039.1

    Status: VALIDATED

    Source sequence(s)
    AC007228, AF269249, BC014280, BP377051
    Consensus CDS
    CCDS12947.1
    UniProtKB/Swiss-Prot
    Q9NQZ8
    Related
    ENSP00000328245.5, ENST00000328070.10
    Conserved Domains (2) summary
    COG5048
    Location:110479
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:272292
    ZF_C2H2; C2H2 Zn finger [structural motif]

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20210514

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000019.10 Reference GRCh38.p13 Primary Assembly

    Range
    56595302..56624486
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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