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ABHD17C abhydrolase domain containing 17C, depalmitoylase [ Homo sapiens (human) ]

Gene ID: 58489, updated on 22-Jan-2020

Summary

Official Symbol
ABHD17Cprovided by HGNC
Official Full Name
abhydrolase domain containing 17C, depalmitoylaseprovided by HGNC
Primary source
HGNC:HGNC:26925
See related
Ensembl:ENSG00000136379 MIM:617944
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
FAM108C1
Expression
Broad expression in colon (RPKM 37.1), stomach (RPKM 19.2) and 20 other tissues See more
Orthologs

Genomic context

See ABHD17C in Genome Data Viewer
Location:
15q25.1
Exon count:
3
Annotation release Status Assembly Chr Location
109.20191205 current GRCh38.p13 (GCF_000001405.39) 15 NC_000015.10 (80695310..80755621)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 15 NC_000015.9 (80987635..81047962)

Chromosome 15 - NC_000015.10Genomic Context describing neighboring genes Neighboring gene aryl hydrocarbon receptor nuclear translocator 2 Neighboring gene microRNA 5572 Neighboring gene RNA, U6 small nuclear 380, pseudogene Neighboring gene cell migration inducing hyaluronidase 1 Neighboring gene microRNA 549a Neighboring gene uncharacterized LOC107984749

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • FLJ34461, MGC131546

Gene Ontology Provided by GOA

Function Evidence Code Pubs
palmitoyl-(protein) hydrolase activity IMP
Inferred from Mutant Phenotype
more info
PubMed 
Process Evidence Code Pubs
negative regulation of protein localization to microtubule IEA
Inferred from Electronic Annotation
more info
 
positive regulation of protein localization to endosome IEA
Inferred from Electronic Annotation
more info
 
protein depalmitoylation IEA
Inferred from Electronic Annotation
more info
 
protein palmitoylation IGI
Inferred from Genetic Interaction
more info
PubMed 
protein palmitoylation IMP
Inferred from Mutant Phenotype
more info
PubMed 
regulation of postsynapse organization IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
cell junction IEA
Inferred from Electronic Annotation
more info
 
dendritic spine IEA
Inferred from Electronic Annotation
more info
 
glutamatergic synapse IEA
Inferred from Electronic Annotation
more info
 
postsynaptic density IEA
Inferred from Electronic Annotation
more info
 
postsynaptic membrane IEA
Inferred from Electronic Annotation
more info
 
recycling endosome membrane IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
alpha/beta hydrolase domain-containing protein 17C
Names
abhydrolase domain containing 17C
abhydrolase domain-containing protein 17C
abhydrolase domain-containing protein FAM108C1
family with sequence similarity 108, member C1
protein ABHD17C
NP_067037.1

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_021214.2NP_067037.1  alpha/beta hydrolase domain-containing protein 17C

    See identical proteins and their annotated locations for NP_067037.1

    Status: VALIDATED

    Source sequence(s)
    AC023302, AL390079, BC059401
    Consensus CDS
    CCDS45323.1
    UniProtKB/Swiss-Prot
    Q6PCB6
    Related
    ENSP00000258884.4, ENST00000258884.5
    Conserved Domains (1) summary
    COG1073
    Location:134326
    FrsA; Fermentation-respiration switch protein FrsA, has esterase activity, DUF1100 family [Signal transduction mechanisms]

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20191205

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000015.10 Reference GRCh38.p13 Primary Assembly

    Range
    80695310..80755621
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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