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Rab37 RAB37, member RAS oncogene family [ Mus musculus (house mouse) ]

Gene ID: 58222, updated on 13-Dec-2022

Summary

Official Symbol
Rab37provided by MGI
Official Full Name
RAB37, member RAS oncogene familyprovided by MGI
Primary source
MGI:MGI:1929945
See related
Ensembl:ENSMUSG00000020732 AllianceGenome:MGI:1929945
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
B230331O03Rik; B230354I04Rik
Summary
Predicted to enable GTPase activity. Predicted to act upstream of or within protein transport. Located in secretory granule. Is expressed in brain and retina. Orthologous to human RAB37 (RAB37, member RAS oncogene family). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Broad expression in cerebellum adult (RPKM 5.8), frontal lobe adult (RPKM 3.4) and 16 other tissues See more
Orthologs
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Genomic context

See Rab37 in Genome Data Viewer
Location:
11; 11 E2
Exon count:
11
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 11 NC_000077.7 (114982257..115053066)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 11 NC_000077.6 (115091331..115162773)

Chromosome 11 - NC_000077.7Genomic Context describing neighboring genes Neighboring gene CD300 molecule like family member D3 Neighboring gene CD300E molecule Neighboring gene CD300 molecule like family member F Neighboring gene NHERF family PDZ scaffold protein 1 Neighboring gene transmembrane protein 104 Neighboring gene N-acetyltransferase 9 (GCN5-related, putative)

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • MGC157622

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables GTP binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables GTPase activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables GTPase activity ISS
Inferred from Sequence or Structural Similarity
more info
PubMed 
enables nucleotide binding IEA
Inferred from Electronic Annotation
more info
 
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
acts_upstream_of_or_within protein transport IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
is_active_in Golgi apparatus IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in cytoplasmic vesicle IEA
Inferred from Electronic Annotation
more info
 
located_in endoplasmic reticulum-Golgi intermediate compartment ISO
Inferred from Sequence Orthology
more info
 
is_active_in endosome IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in secretory granule IDA
Inferred from Direct Assay
more info
PubMed 

General protein information

Preferred Names
ras-related protein Rab-37
Names
GTPase Rab37
RAB37, member of RAS oncogene family

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001163753.1NP_001157225.1  ras-related protein Rab-37 isoform 2

    See identical proteins and their annotated locations for NP_001157225.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) differs at the 5' end, and is missing two in-frame coding exons compared to variant 1. This results in a shorter isoform (2) with a distinct N-terminus compared to isoform 1.
    Source sequence(s)
    AK046260, BB084455
    Consensus CDS
    CCDS48979.1
    UniProtKB/TrEMBL
    A0A8C6ID99, Q8BQX0
    Related
    ENSMUSP00000065016.5, ENSMUST00000067754.11
    Conserved Domains (1) summary
    cd04112
    Location:23213
    Rab26; Rab GTPase family 26 (Rab26)
  2. NM_021411.4NP_067386.3  ras-related protein Rab-37 isoform 1

    See identical proteins and their annotated locations for NP_067386.3

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) encodes the longer isoform (1).
    Source sequence(s)
    AK040216, AK050483, BB084455, BY131048
    Consensus CDS
    CCDS25620.1
    UniProtKB/Swiss-Prot
    Q9JKM7
    UniProtKB/TrEMBL
    A0A6P5QMN4, A0A8C6IA11, Q544E8
    Related
    ENSMUSP00000021076.6, ENSMUST00000021076.6
    Conserved Domains (1) summary
    cd04112
    Location:31220
    Rab26; Rab GTPase family 26 (Rab26)

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000077.7 Reference GRCm39 C57BL/6J

    Range
    114982257..115053066
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_036156872.1XP_036012765.1  ras-related protein Rab-37 isoform X1

    Conserved Domains (1) summary
    cl38936
    Location:31144
    P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases

RNA

  1. XR_003949483.2 RNA Sequence