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Prokr1 prokineticin receptor 1 [ Mus musculus (house mouse) ]

Gene ID: 58182, updated on 8-Dec-2018

Summary

Official Symbol
Prokr1provided by MGI
Official Full Name
prokineticin receptor 1provided by MGI
Primary source
MGI:MGI:1929676
See related
Ensembl:ENSMUSG00000049409
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Pkr1; Gpr73; Pk-r1; EG-VEGFR1
Expression
Broad expression in genital fat pad adult (RPKM 3.3), liver E14.5 (RPKM 2.0) and 19 other tissues See more
Orthologs

Genomic context

See Prokr1 in Genome Data Viewer
Location:
6; 6 D1
Exon count:
3
Annotation release Status Assembly Chr Location
106 current GRCm38.p4 (GCF_000001635.24) 6 NC_000072.6 (87578589..87590770, complement)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 6 NC_000072.5 (87528586..87540695, complement)

Chromosome 6 - NC_000072.6Genomic Context describing neighboring genes Neighboring gene bone morphogenetic protein 10 Neighboring gene Rho GTPase activating protein 25 Neighboring gene predicted gene, 34222 Neighboring gene predicted gene, 34312 Neighboring gene predicted gene, 46964 Neighboring gene aprataxin and PNKP like factor

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)

Pathways from BioSystems

General gene information

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
G protein-coupled receptor activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
G protein-coupled receptor activity ISO
Inferred from Sequence Orthology
more info
 
G protein-coupled receptor activity TAS
Traceable Author Statement
more info
PubMed 
neuropeptide Y receptor activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
G protein-coupled receptor signaling pathway IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
G protein-coupled receptor signaling pathway TAS
Traceable Author Statement
more info
PubMed 
circadian rhythm IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
circadian rhythm TAS
Traceable Author Statement
more info
PubMed 
coronary vasculature development TAS
Traceable Author Statement
more info
PubMed 
negative regulation of apoptotic process ISO
Inferred from Sequence Orthology
more info
 
signal transduction IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
integral component of membrane IEA
Inferred from Electronic Annotation
more info
 
integral component of plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
membrane IEA
Inferred from Electronic Annotation
more info
 
plasma membrane IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
prokineticin receptor 1
Names
G-protein coupled receptor 73

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001355655.1NP_001342584.1  prokineticin receptor 1

    Status: VALIDATED

    Source sequence(s)
    AC125171
    Conserved Domains (1) summary
    cd15204
    Location:63353
    7tmA_prokineticin-R; prokineticin receptors, member of the class A family of seven-transmembrane G protein-coupled receptors
  2. NM_021381.4NP_067356.2  prokineticin receptor 1

    See identical proteins and their annotated locations for NP_067356.2

    Status: VALIDATED

    Source sequence(s)
    AC125171, BC059003
    Consensus CDS
    CCDS20323.1
    UniProtKB/Swiss-Prot
    Q9JKL1
    Related
    ENSMUSP00000059034.7, ENSMUST00000050887.8
    Conserved Domains (1) summary
    cd15204
    Location:63353
    7tmA_prokineticin-R; prokineticin receptors, member of the class A family of seven-transmembrane G protein-coupled receptors

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38.p4 C57BL/6J

Genomic

  1. NC_000072.6 Reference GRCm38.p4 C57BL/6J

    Range
    87578589..87590770 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006506431.3XP_006506494.1  prokineticin receptor 1 isoform X1

    UniProtKB/Swiss-Prot
    Q9JKL1
    Related
    ENSMUSP00000144999.1, ENSMUST00000204682.2
    Conserved Domains (1) summary
    cd15204
    Location:63353
    7tmA_prokineticin-R; prokineticin receptors, member of the class A family of seven-transmembrane G protein-coupled receptors
  2. XM_006506433.3XP_006506496.1  prokineticin receptor 1 isoform X2

    Conserved Domains (1) summary
    pfam00001
    Location:1219
    7tm_1; 7 transmembrane receptor (rhodopsin family)
  3. XM_006506432.3XP_006506495.1  prokineticin receptor 1 isoform X1

    See identical proteins and their annotated locations for XP_006506495.1

    UniProtKB/Swiss-Prot
    Q9JKL1
    Conserved Domains (1) summary
    cd15204
    Location:63353
    7tmA_prokineticin-R; prokineticin receptors, member of the class A family of seven-transmembrane G protein-coupled receptors
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