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Prokr1 prokineticin receptor 1 [ Mus musculus (house mouse) ]

Gene ID: 58182, updated on 28-Jun-2021

Summary

Official Symbol
Prokr1provided by MGI
Official Full Name
prokineticin receptor 1provided by MGI
Primary source
MGI:MGI:1929676
See related
Ensembl:ENSMUSG00000049409
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Pk; Gpr; Pkr1; Gpr73; Pk-r1; EG-VEGF; EG-VEGFR1
Expression
Broad expression in genital fat pad adult (RPKM 3.3), liver E14.5 (RPKM 2.0) and 19 other tissues See more
Orthologs
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Genomic context

See Prokr1 in Genome Data Viewer
Location:
6; 6 D1
Exon count:
5
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 6 NC_000072.7 (87555568..87567741, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 6 NC_000072.6 (87578586..87590762, complement)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 6 NC_000072.5 (87528586..87540695, complement)

Chromosome 6 - NC_000072.7Genomic Context describing neighboring genes Neighboring gene bone morphogenetic protein 10 Neighboring gene Rho GTPase activating protein 25 Neighboring gene predicted gene, 34222 Neighboring gene predicted gene, 34312 Neighboring gene aprataxin and PNKP like factor Neighboring gene predicted gene, 46964

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)

Pathways from PubChem

General gene information

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables G protein-coupled receptor activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables G protein-coupled receptor activity ISO
Inferred from Sequence Orthology
more info
 
enables G protein-coupled receptor activity TAS
Traceable Author Statement
more info
PubMed 
enables neuropeptide Y receptor activity IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
located_in integral component of membrane IEA
Inferred from Electronic Annotation
more info
 
is_active_in integral component of plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
prokineticin receptor 1
Names
G-protein coupled receptor 73

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001355655.1NP_001342584.1  prokineticin receptor 1

    Status: VALIDATED

    Source sequence(s)
    AC125171
    Consensus CDS
    CCDS20323.1
    Related
    ENSMUSP00000144999.2, ENSMUST00000204682.3
    Conserved Domains (1) summary
    cd15204
    Location:63353
    7tmA_prokineticin-R; prokineticin receptors, member of the class A family of seven-transmembrane G protein-coupled receptors
  2. NM_021381.4NP_067356.2  prokineticin receptor 1

    See identical proteins and their annotated locations for NP_067356.2

    Status: VALIDATED

    Source sequence(s)
    AC125171, BC059003
    Consensus CDS
    CCDS20323.1
    UniProtKB/Swiss-Prot
    Q9JKL1
    Related
    ENSMUSP00000059034.8, ENSMUST00000050887.9
    Conserved Domains (1) summary
    cd15204
    Location:63353
    7tmA_prokineticin-R; prokineticin receptors, member of the class A family of seven-transmembrane G protein-coupled receptors

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000072.7 Reference GRCm39 C57BL/6J

    Range
    87555568..87567741 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006506433.5XP_006506496.1  prokineticin receptor 1 isoform X2

    Conserved Domains (2) summary
    cd14964
    Location:1848
    7tm_GPCRs; TM helix 3 [structural motif]
    cl28897
    Location:1234
    7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily
  2. XM_006506432.5XP_006506495.1  prokineticin receptor 1 isoform X1

    See identical proteins and their annotated locations for XP_006506495.1

    UniProtKB/Swiss-Prot
    Q9JKL1
    Conserved Domains (1) summary
    cd15204
    Location:63353
    7tmA_prokineticin-R; prokineticin receptors, member of the class A family of seven-transmembrane G protein-coupled receptors
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