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Rhbg Rhesus blood group-associated B glycoprotein [ Mus musculus (house mouse) ]

Gene ID: 58176, updated on 19-Jun-2024

Summary

Official Symbol
Rhbgprovided by MGI
Official Full Name
Rhesus blood group-associated B glycoproteinprovided by MGI
Primary source
MGI:MGI:1927379
See related
Ensembl:ENSMUSG00000104445 AllianceGenome:MGI:1927379
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Summary
Enables ammonium transmembrane transporter activity. Involved in ammonium transmembrane transport. Located in basolateral plasma membrane. Is expressed in genitourinary system. Orthologous to human RHBG (Rh family B glycoprotein). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in kidney adult (RPKM 38.4), large intestine adult (RPKM 18.5) and 10 other tissues See more
Orthologs
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Genomic context

See Rhbg in Genome Data Viewer
Location:
3 F1; 3 38.78 cM
Exon count:
10
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 3 NC_000069.7 (88150181..88162046, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 3 NC_000069.6 (88242874..88254739, complement)

Chromosome 3 - NC_000069.7Genomic Context describing neighboring genes Neighboring gene predicted gene 3764 Neighboring gene microRNA 3093 Neighboring gene microRNA 9b-1 Neighboring gene microRNA 9-1 Neighboring gene STARR-seq mESC enhancer starr_08177 Neighboring gene VISTA enhancer mm474 Neighboring gene STARR-seq mESC enhancer starr_08178 Neighboring gene STARR-seq mESC enhancer starr_08179 Neighboring gene TSSK6 activating co-chaperone Neighboring gene chaperonin containing TCP1 subunit 3

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

Related articles in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (2) 
  • Gene trapped (1) 
  • Targeted (2)  1 citation

Pathways from PubChem

General gene information

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables ammonium channel activity IBA
Inferred from Biological aspect of Ancestor
more info
 
enables ammonium channel activity IDA
Inferred from Direct Assay
more info
PubMed 
enables ammonium channel activity ISO
Inferred from Sequence Orthology
more info
 
enables ankyrin binding ISO
Inferred from Sequence Orthology
more info
 
enables carbon dioxide transmembrane transporter activity ISO
Inferred from Sequence Orthology
more info
 
Process Evidence Code Pubs
involved_in ammonium homeostasis IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in ammonium transmembrane transport IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in ammonium transmembrane transport IDA
Inferred from Direct Assay
more info
PubMed 
involved_in ammonium transmembrane transport ISO
Inferred from Sequence Orthology
more info
 
involved_in transepithelial ammonium transport ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
located_in basolateral plasma membrane IDA
Inferred from Direct Assay
more info
PubMed 
located_in basolateral plasma membrane ISO
Inferred from Sequence Orthology
more info
 
located_in membrane IDA
Inferred from Direct Assay
more info
PubMed 
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in plasma membrane ISO
Inferred from Sequence Orthology
more info
 
located_in plasma membrane ISS
Inferred from Sequence or Structural Similarity
more info
PubMed 
located_in spectrin-associated cytoskeleton ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
ammonium transporter Rh type B
Names
Rh type B glycoprotein
rh family type B glycoprotein
rhesus blood group family type B glycoprotein

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_021375.3NP_067350.2  ammonium transporter Rh type B

    See identical proteins and their annotated locations for NP_067350.2

    Status: PROVISIONAL

    Source sequence(s)
    AK081882
    Consensus CDS
    CCDS17466.1
    UniProtKB/Swiss-Prot
    Q8BUX5, Q9QXP1
    UniProtKB/TrEMBL
    E9Q2A2
    Related
    ENSMUSP00000130767.2, ENSMUST00000171887.4
    Conserved Domains (1) summary
    cl03012
    Location:58403
    Ammonium_transp; Ammonium Transporter Family

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000069.7 Reference GRCm39 C57BL/6J

    Range
    88150181..88162046 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006501826.4XP_006501889.1  ammonium transporter Rh type B isoform X1

    UniProtKB/TrEMBL
    E9Q2A2
    Conserved Domains (1) summary
    cl03012
    Location:58362
    Ammonium_transp; Ammonium Transporter Family