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bmpr1aa bone morphogenetic protein receptor, type IAa [ Danio rerio (zebrafish) ]

Gene ID: 58145, updated on 25-Aug-2020

Summary

Official Symbol
bmpr1aaprovided by ZNC
Official Full Name
bone morphogenetic protein receptor, type IAaprovided by ZNC
Primary source
ZFIN:ZDB-GENE-000502-1
See related
Ensembl:ENSDARG00000019728
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
BR; al; alk; bmp; BR1a; alk3; zBMP; alk3tr; bmpr1a; BMPR-IA; zgc:136731
Orthologs

Genomic context

See bmpr1aa in Genome Data Viewer
Location:
chromosome: 13
Exon count:
18
Annotation release Status Assembly Chr Location
106 current GRCz11 (GCF_000002035.6) 13 NC_007124.7 (22555763..22619802)
105 previous assembly GRCz10 (GCF_000002035.5) 13 NC_007124.6 (22425229..22489352)
103 previous assembly Zv9 (GCF_000002035.4) 13 NC_007124.5 (22695962..22760014)

Chromosome 13 - NC_007124.7Genomic Context describing neighboring genes Neighboring gene opsin 4a (melanopsin) Neighboring gene LIM domain binding 3a Neighboring gene multimerin 2a Neighboring gene zgc:193505 Neighboring gene synuclein, gamma a

Genomic regions, transcripts, and products

Pathways from PubChem

General gene information

Markers

Homology

Clone Names

  • MGC136731

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
ATP binding IEA
Inferred from Electronic Annotation
more info
 
SMAD binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
kinase activity IEA
Inferred from Electronic Annotation
more info
 
nucleotide binding IEA
Inferred from Electronic Annotation
more info
 
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
protein kinase activity IEA
Inferred from Electronic Annotation
more info
 
protein serine/threonine kinase activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
protein serine/threonine kinase activity IEA
Inferred from Electronic Annotation
more info
 
transferase activity IEA
Inferred from Electronic Annotation
more info
 
transforming growth factor beta receptor activity, type I IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
transmembrane receptor protein serine/threonine kinase activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
BMP signaling pathway IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
BMP signaling pathway IGI
Inferred from Genetic Interaction
more info
PubMed 
cardiac cell fate specification IGI
Inferred from Genetic Interaction
more info
PubMed 
cellular response to growth factor stimulus IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
determination of heart left/right asymmetry IGI
Inferred from Genetic Interaction
more info
PubMed 
determination of heart left/right asymmetry IMP
Inferred from Mutant Phenotype
more info
PubMed 
dorsal/ventral pattern formation IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
dorsal/ventral pattern formation IGI
Inferred from Genetic Interaction
more info
PubMed 
embryonic heart tube left/right pattern formation IMP
Inferred from Mutant Phenotype
more info
 
heart looping IMP
Inferred from Mutant Phenotype
more info
 
left/right pattern formation IGI
Inferred from Genetic Interaction
more info
PubMed 
left/right pattern formation IMP
Inferred from Mutant Phenotype
more info
PubMed 
lymph vessel development IGI
Inferred from Genetic Interaction
more info
PubMed 
phosphorylation IEA
Inferred from Electronic Annotation
more info
 
protein phosphorylation IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
protein phosphorylation IEA
Inferred from Electronic Annotation
more info
 
transmembrane receptor protein serine/threonine kinase signaling pathway IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
BMP receptor complex IDA
Inferred from Direct Assay
more info
PubMed 
integral component of membrane IEA
Inferred from Electronic Annotation
more info
 
membrane IEA
Inferred from Electronic Annotation
more info
 
plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
receptor complex IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 

General protein information

Preferred Names
bone morphogenetic protein receptor type-1A; bone morphogenetic protein receptor, type IAa
Names
alk3a
bone morphogenetic protein receptor, type 1a
bone morphogenetic protein receptor, type 1aa
NP_571696.2
XP_005156936.1
XP_009305624.1
XP_021336337.1
XP_021336338.1
XP_021336339.1
XP_021336340.1

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_131621.3NP_571696.2  bone morphogenetic protein receptor, type IAa precursor

    See identical proteins and their annotated locations for NP_571696.2

    Status: VALIDATED

    Source sequence(s)
    BX005174, CT573135
    UniProtKB/TrEMBL
    Q1RLX1
    Related
    ENSDARP00000015287.7, ENSDART00000026768.9
    Conserved Domains (3) summary
    pfam01064
    Location:59134
    Activin_recp; Activin types I and II receptor domain
    pfam08515
    Location:200227
    TGF_beta_GS; Transforming growth factor beta type I GS-motif
    cl21453
    Location:233519
    PKc_like; Protein Kinases, catalytic domain

RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007124.7 Reference GRCz11 Primary Assembly

    Range
    22555763..22619802
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005156879.4XP_005156936.1  bone morphogenetic protein receptor type-1A isoform X2

    See identical proteins and their annotated locations for XP_005156936.1

    UniProtKB/TrEMBL
    B3DJG0
    Related
    ENSDARP00000152766.1, ENSDART00000183723.1
    Conserved Domains (3) summary
    pfam01064
    Location:58133
    Activin_recp; Activin types I and II receptor domain
    pfam08515
    Location:199226
    TGF_beta_GS; Transforming growth factor beta type I GS-motif
    cl21453
    Location:232518
    PKc_like; Protein Kinases, catalytic domain
  2. XM_009307349.3XP_009305624.1  bone morphogenetic protein receptor type-1A isoform X1

    See identical proteins and their annotated locations for XP_009305624.1

    UniProtKB/TrEMBL
    Q1RLX1
    Related
    ENSDARP00000150931.1, ENSDART00000193633.1
    Conserved Domains (3) summary
    pfam01064
    Location:59134
    Activin_recp; Activin types I and II receptor domain
    pfam08515
    Location:200227
    TGF_beta_GS; Transforming growth factor beta type I GS-motif
    cl21453
    Location:233519
    PKc_like; Protein Kinases, catalytic domain
  3. XM_021480665.1XP_021336340.1  bone morphogenetic protein receptor type-1A isoform X3

    Conserved Domains (2) summary
    pfam08515
    Location:100127
    TGF_beta_GS; Transforming growth factor beta type I GS-motif
    cl21453
    Location:133419
    PKc_like; Protein Kinases, catalytic domain
  4. XM_021480662.1XP_021336337.1  bone morphogenetic protein receptor type-1A isoform X1

    Conserved Domains (3) summary
    pfam01064
    Location:59134
    Activin_recp; Activin types I and II receptor domain
    pfam08515
    Location:200227
    TGF_beta_GS; Transforming growth factor beta type I GS-motif
    cl21453
    Location:233519
    PKc_like; Protein Kinases, catalytic domain
  5. XM_021480664.1XP_021336339.1  bone morphogenetic protein receptor type-1A isoform X2

    Conserved Domains (3) summary
    pfam01064
    Location:58133
    Activin_recp; Activin types I and II receptor domain
    pfam08515
    Location:199226
    TGF_beta_GS; Transforming growth factor beta type I GS-motif
    cl21453
    Location:232518
    PKc_like; Protein Kinases, catalytic domain
  6. XM_021480663.1XP_021336338.1  bone morphogenetic protein receptor type-1A isoform X1

    Conserved Domains (3) summary
    pfam01064
    Location:59134
    Activin_recp; Activin types I and II receptor domain
    pfam08515
    Location:200227
    TGF_beta_GS; Transforming growth factor beta type I GS-motif
    cl21453
    Location:233519
    PKc_like; Protein Kinases, catalytic domain

Reference GRCz11 ALT_DRER_TU_1

Genomic

  1. NW_018394884.1 Reference GRCz11 ALT_DRER_TU_1

    Range
    36379..63256
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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