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notch2 notch receptor 2 [ Danio rerio (zebrafish) ]

Gene ID: 58065, updated on 17-Nov-2020

Summary

Official Symbol
notch2provided by ZNC
Official Full Name
notch receptor 2provided by ZNC
Primary source
ZFIN:ZDB-GENE-000329-4
See related
Ensembl:ENSDARG00000043130
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
notc; notch6; sb:cb88; sb:cb884
Orthologs

Genomic context

See notch2 in Genome Data Viewer
Location:
chromosome: 8
Exon count:
34
Annotation release Status Assembly Chr Location
106 current GRCz11 (GCF_000002035.6) 8 NC_007119.7 (19548985..19619792)
105 previous assembly GRCz10 (GCF_000002035.5) 8 NC_007119.6 (19516900..19587707)
103 previous assembly Zv9 (GCF_000002035.4) 8 NC_007119.5 (20107974..20157810)

Chromosome 8 - NC_007119.7Genomic Context describing neighboring genes Neighboring gene si:ch73-281k2.5 Neighboring gene SEC22 homolog B, vesicle trafficking protein b Neighboring gene solute carrier family 35 member A3a Neighboring gene family with sequence similarity 78 member Bb

Genomic regions, transcripts, and products

Pathways from PubChem

General gene information

Markers

Homology

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
Notch binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
calcium ion binding IEA
Inferred from Electronic Annotation
more info
 
metal ion binding IEA
Inferred from Electronic Annotation
more info
 
signaling receptor activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
Notch signaling pathway IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Notch signaling pathway IEA
Inferred from Electronic Annotation
more info
 
cartilage development involved in endochondral bone morphogenesis IGI
Inferred from Genetic Interaction
more info
PubMed 
cell differentiation IEA
Inferred from Electronic Annotation
more info
 
endocrine pancreas development IMP
Inferred from Mutant Phenotype
more info
PubMed 
face morphogenesis IGI
Inferred from Genetic Interaction
more info
PubMed 
glucose homeostasis IMP
Inferred from Mutant Phenotype
more info
PubMed 
liver development IGI
Inferred from Genetic Interaction
more info
PubMed 
lymphangiogenesis IMP
Inferred from Mutant Phenotype
more info
PubMed 
multicellular organism development IEA
Inferred from Electronic Annotation
more info
 
pancreas regeneration IMP
Inferred from Mutant Phenotype
more info
PubMed 
regulation of developmental process IEA
Inferred from Electronic Annotation
more info
 
regulation of transcription, DNA-templated IEA
Inferred from Electronic Annotation
more info
 
tissue regeneration IEP
Inferred from Expression Pattern
more info
PubMed 
vasculature development IMP
Inferred from Mutant Phenotype
more info
PubMed 
Component Evidence Code Pubs
integral component of membrane IEA
Inferred from Electronic Annotation
more info
 
membrane IEA
Inferred from Electronic Annotation
more info
 
nucleus IEA
Inferred from Electronic Annotation
more info
 
plasma membrane IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
neurogenic locus notch homolog protein 2
Names
notch 2
notch homolog 2
notch receptor protein 6

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001115094.2NP_001108566.2  neurogenic locus notch homolog protein 2 precursor

    Status: VALIDATED

    Source sequence(s)
    EH438786, FP016062
    UniProtKB/TrEMBL
    F1RCH4
    Related
    ENSDARP00000112112.2, ENSDART00000123104.4

RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007119.7 Reference GRCz11 Primary Assembly

    Range
    19548985..19619792
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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