NEW
Try the new Transcript table
These reference sequences exist independently of genome builds. Explain
These reference sequences are curated independently of the genome
annotation cycle, so their versions may not match the RefSeq versions in the current
genome build. Identify version mismatches by comparing the version of the RefSeq in
this section to the one reported in Genomic regions,
transcripts, and products above.
Genomic
-
NG_029966.2 RefSeqGene
- Range
-
5000..1053767
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
mRNA and Protein(s)
-
NM_001308267.2 → NP_001295196.1 receptor-type tyrosine-protein phosphatase N2 isoform 4 precursor
Status: REVIEWED
- Description
- Transcript Variant: This variant (4) lacks an alternate in-frame exon in the 5' coding region, compared to variant 1, resulting in an isoform (4) that is shorter than isoform 1.
- Source sequence(s)
-
AC005481, AC006372, AC011899, AC078942, AC093662, AC093856
- Consensus CDS
-
CCDS78294.1
- UniProtKB/Swiss-Prot
-
Q92932
- UniProtKB/TrEMBL
- E7EM83, I6L9F8
- Related
- ENSP00000387114.1, ENST00000409483.5
- Conserved Domains (4) summary
-
- smart00194
Location:707 → 966
- PTPc; Protein tyrosine phosphatase, catalytic domain
- cd00047
Location:734 → 966
- PTPc; Protein tyrosine phosphatases (PTP) catalyze the dephosphorylation of phosphotyrosine peptides; they regulate phosphotyrosine levels in signal transduction pathways. The depth of the active site cleft renders the enzyme specific for phosphorylated Tyr ...
- pfam11548
Location:474 → 559
- Receptor_IA-2; Protein-tyrosine phosphatase receptor IA-2
- pfam14948
Location:55 → 100
- RESP18; RESP18 domain
-
NM_001308268.2 → NP_001295197.1 receptor-type tyrosine-protein phosphatase N2 isoform 5
Status: REVIEWED
- Description
- Transcript Variant: This variant (5) contains an alternate 5' terminal exon, and it thus differs in the 5' UTR and 5' coding region, compared to variant 1. The encoded isoform (5) has a distinct N-terminus and is longer than isoform 1.
- Source sequence(s)
-
AC005481, AC006372, AC011899, AC019043, AC078942, AC093856
- UniProtKB/Swiss-Prot
-
Q92932
- UniProtKB/TrEMBL
-
I6L9F8
- Conserved Domains (4) summary
-
- smart00194
Location:768 → 1027
- PTPc; Protein tyrosine phosphatase, catalytic domain
- cd00047
Location:795 → 1027
- PTPc; Protein tyrosine phosphatases (PTP) catalyze the dephosphorylation of phosphotyrosine peptides; they regulate phosphotyrosine levels in signal transduction pathways. The depth of the active site cleft renders the enzyme specific for phosphorylated Tyr ...
- pfam11548
Location:535 → 620
- Receptor_IA-2; Protein-tyrosine phosphatase receptor IA-2
- pfam14948
Location:82 → 161
- RESP18; RESP18 domain
-
NM_002847.5 → NP_002838.2 receptor-type tyrosine-protein phosphatase N2 isoform 1 precursor
See identical proteins and their annotated locations for NP_002838.2
Status: REVIEWED
- Description
- Transcript Variant: This variant (1) encodes isoform 1.
- Source sequence(s)
-
AC005481, AC006372, AC011899, AC019043, AC078942, AC093662, AC093856
- Consensus CDS
-
CCDS5947.1
- UniProtKB/Swiss-Prot
- Q92932, Q9Y4I6
- UniProtKB/TrEMBL
-
I6L9F8
- Related
- ENSP00000374069.4, ENST00000389418.9
- Conserved Domains (4) summary
-
- smart00194
Location:745 → 1004
- PTPc; Protein tyrosine phosphatase, catalytic domain
- cd00047
Location:772 → 1004
- PTPc; Protein tyrosine phosphatases (PTP) catalyze the dephosphorylation of phosphotyrosine peptides; they regulate phosphotyrosine levels in signal transduction pathways. The depth of the active site cleft renders the enzyme specific for phosphorylated Tyr ...
- pfam11548
Location:512 → 597
- Receptor_IA-2; Protein-tyrosine phosphatase receptor IA-2
- pfam14948
Location:59 → 138
- RESP18; RESP18 domain
-
NM_130842.4 → NP_570857.2 receptor-type tyrosine-protein phosphatase N2 isoform 2 precursor
Status: REVIEWED
- Description
- Transcript Variant: This variant (2) lacks an alternate in-frame exon in the 5' coding region, compared to variant 1, resulting in an isoform (2) that is shorter than isoform 1.
- Source sequence(s)
-
AC005481, AC006372, AC011899, AC019043, AC093662, AC093856
- Consensus CDS
-
CCDS5948.1
- UniProtKB/Swiss-Prot
-
Q92932
- Related
- ENSP00000374067.4, ENST00000389416.8
- Conserved Domains (4) summary
-
- smart00194
Location:728 → 987
- PTPc; Protein tyrosine phosphatase, catalytic domain
- cd00047
Location:755 → 987
- PTPc; Protein tyrosine phosphatases (PTP) catalyze the dephosphorylation of phosphotyrosine peptides; they regulate phosphotyrosine levels in signal transduction pathways. The depth of the active site cleft renders the enzyme specific for phosphorylated Tyr ...
- pfam11548
Location:495 → 580
- Receptor_IA-2; Protein-tyrosine phosphatase receptor IA-2
- pfam14948
Location:42 → 121
- RESP18; RESP18 domain
-
NM_130843.4 → NP_570858.2 receptor-type tyrosine-protein phosphatase N2 isoform 3 precursor
Status: REVIEWED
- Description
- Transcript Variant: This variant (3) lacks an alternate in-frame exon in the central coding region, compared to variant 1, resulting in an isoform (3) that is shorter than isoform 1.
- Source sequence(s)
-
AC005481, AC006372, AC011899, AC019043, AC078942, AC093662, AC093856
- Consensus CDS
-
CCDS5949.1
- UniProtKB/Swiss-Prot
-
Q92932
- Related
- ENSP00000374064.3, ENST00000389413.7
- Conserved Domains (4) summary
-
- smart00194
Location:716 → 975
- PTPc; Protein tyrosine phosphatase, catalytic domain
- cd00047
Location:743 → 975
- PTPc; Protein tyrosine phosphatases (PTP) catalyze the dephosphorylation of phosphotyrosine peptides; they regulate phosphotyrosine levels in signal transduction pathways. The depth of the active site cleft renders the enzyme specific for phosphorylated Tyr ...
- pfam11548
Location:516 → 568
- Receptor_IA-2; Protein-tyrosine phosphatase receptor IA-2
- pfam14948
Location:59 → 138
- RESP18; RESP18 domain
The following sections contain reference sequences that belong to a
specific genome build. Explain
This section includes genomic Reference
Sequences (RefSeqs) from all assemblies on which this gene is annotated, such as
RefSeqs for chromosomes and scaffolds (contigs) from both reference and alternate
assemblies. Model RNAs and proteins are also reported here.
Reference GRCh38.p14 Primary Assembly
Genomic
-
NC_000007.14 Reference GRCh38.p14 Primary Assembly
- Range
-
157539056..158587823 complement
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
mRNA and Protein(s)
-
XM_047420678.1 → XP_047276634.1 receptor-type tyrosine-protein phosphatase N2 isoform X1
-
XM_047420679.1 → XP_047276635.1 receptor-type tyrosine-protein phosphatase N2 isoform X3
-
XM_017012475.1 → XP_016867964.1 receptor-type tyrosine-protein phosphatase N2 isoform X2
-
XM_011516446.2 → XP_011514748.1 receptor-type tyrosine-protein phosphatase N2 isoform X5
- Conserved Domains (3) summary
-
- pfam11548
Location:512 → 597
- Receptor_IA-2; Protein-tyrosine phosphatase receptor IA-2
- pfam14948
Location:59 → 138
- RESP18; RESP18 domain
- cl21483
Location:772 → 832
- PTPc; Protein tyrosine phosphatases (PTP) catalyze the dephosphorylation of phosphotyrosine peptides; they regulate phosphotyrosine levels in signal transduction pathways. The depth of the active site cleft renders the enzyme specific for phosphorylated Tyr ...
-
XM_017012476.2 → XP_016867965.1 receptor-type tyrosine-protein phosphatase N2 isoform X4
-
XM_011516447.3 → XP_011514749.1 receptor-type tyrosine-protein phosphatase N2 isoform X6
- Conserved Domains (2) summary
-
- pfam11548
Location:512 → 575
- Receptor_IA-2; Protein-tyrosine phosphatase receptor IA-2
- pfam14948
Location:59 → 138
- RESP18; RESP18 domain
-
XM_047420680.1 → XP_047276636.1 receptor-type tyrosine-protein phosphatase N2 isoform X8
-
XM_011516448.4 → XP_011514750.1 receptor-type tyrosine-protein phosphatase N2 isoform X7
- Conserved Domains (2) summary
-
- pfam11548
Location:512 → 575
- Receptor_IA-2; Protein-tyrosine phosphatase receptor IA-2
- pfam14948
Location:59 → 138
- RESP18; RESP18 domain
-
XM_011516449.3 → XP_011514751.1 receptor-type tyrosine-protein phosphatase N2 isoform X9
- Conserved Domains (2) summary
-
- pfam11548
Location:512 → 563
- Receptor_IA-2; Protein-tyrosine phosphatase receptor IA-2
- pfam14948
Location:59 → 138
- RESP18; RESP18 domain
Alternate T2T-CHM13v2.0
Genomic
-
NC_060931.1 Alternate T2T-CHM13v2.0
- Range
-
158727687..159797184 complement
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)