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Angptl4 angiopoietin-like 4 [ Mus musculus (house mouse) ]

Gene ID: 57875, updated on 21-Apr-2018
Official Symbol
Angptl4provided by MGI
Official Full Name
angiopoietin-like 4provided by MGI
Primary source
MGI:MGI:1888999
See related
Ensembl:ENSMUSG00000002289 Vega:OTTMUSG00000037206
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Arp4; Bk89; Fiaf; Ng27; Pgar; Hfarp; Pgarg; Pp1158
Expression
Biased expression in subcutaneous fat pad adult (RPKM 130.4), genital fat pad adult (RPKM 109.0) and 14 other tissues See more
Orthologs
Location:
17; 17 B1
Exon count:
7
Annotation release Status Assembly Chr Location
106 current GRCm38.p4 (GCF_000001635.24) 17 NC_000083.6 (33774900..33781575, complement)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 17 NC_000083.5 (33911845..33918520, complement)

Chromosome 17 - NC_000083.6Genomic Context describing neighboring genes Neighboring gene membrane-associated ring finger (C3HC4) 2 Neighboring gene RAB11B, member RAS oncogene family Neighboring gene KN motif and ankyrin repeat domains 3 Neighboring gene ribosomal protein S28

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enzyme inhibitor activity IDA
Inferred from Direct Assay
more info
PubMed 
identical protein binding ISO
Inferred from Sequence Orthology
more info
 
Process Evidence Code Pubs
angiogenesis IEA
Inferred from Electronic Annotation
more info
 
cellular response to starvation NAS
Non-traceable Author Statement
more info
PubMed 
negative regulation of apoptotic process IDA
Inferred from Direct Assay
more info
PubMed 
negative regulation of apoptotic process ISO
Inferred from Sequence Orthology
more info
 
negative regulation of endothelial cell apoptotic process IDA
Inferred from Direct Assay
more info
PubMed 
negative regulation of lipoprotein lipase activity IDA
Inferred from Direct Assay
more info
PubMed 
negative regulation of lipoprotein lipase activity ISO
Inferred from Sequence Orthology
more info
 
positive regulation of lipid metabolic process NAS
Non-traceable Author Statement
more info
PubMed 
protein homooligomerization ISO
Inferred from Sequence Orthology
more info
 
triglyceride homeostasis IMP
Inferred from Mutant Phenotype
more info
PubMed 
Component Evidence Code Pubs
extracellular region IDA
Inferred from Direct Assay
more info
PubMed 
extracellular region ISO
Inferred from Sequence Orthology
more info
 
extracellular space IDA
Inferred from Direct Assay
more info
PubMed 
extracellular space ISO
Inferred from Sequence Orthology
more info
PubMed 
Preferred Names
angiopoietin-related protein 4
Names
425O18-1
angiopoietin-like protein 4
fasting-induced adipose factor
fibrinogen/angiopoietin-related protein
hepatic fibrinogen/angiopoietin-related protein
major histocompatibility complex region NG27
secreted protein Bk89

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_020581.2NP_065606.2  angiopoietin-related protein 4 precursor

    See identical proteins and their annotated locations for NP_065606.2

    Status: VALIDATED

    Source sequence(s)
    AK014564, AW495750, BY783212
    Consensus CDS
    CCDS28629.1
    UniProtKB/Swiss-Prot
    Q9Z1P8
    Related
    ENSMUSP00000002360.9, OTTMUSP00000053559, ENSMUST00000002360.15, OTTMUST00000095930
    Conserved Domains (2) summary
    cd00087
    Location:187404
    FReD; Fibrinogen-related domains (FReDs); C terminal globular domain of fibrinogen. Fibrinogen is involved in blood clotting, being activated by thrombin to assemble into fibrin clots. The N-termini of 2 times 3 chains come together to form a globular ...
    pfam08702
    Location:104133
    Fib_alpha; Fibrinogen alpha/beta chain family

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38.p4 C57BL/6J

Genomic

  1. NC_000083.6 Reference GRCm38.p4 C57BL/6J

    Range
    33774900..33781575 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Reference GRCm38.p4 129X1/SvJ

Genomic

  1. NT_039662.3 Reference GRCm38.p4 129X1/SvJ

    Range
    23655..30330 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Reference GRCm38.p4 NOD/MrkTac

Genomic

  1. NT_187027.1 Reference GRCm38.p4 NOD/MrkTac

    Range
    90560..97243 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Reference GRCm38.p4 NOD/ShiLtJ

Genomic

  1. NT_187004.1 Reference GRCm38.p4 NOD/ShiLtJ

    Range
    90560..97243 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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