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NCKAP5L NCK associated protein 5 like [ Homo sapiens (human) ]

Gene ID: 57701, updated on 1-Jun-2020

Summary

Official Symbol
NCKAP5Lprovided by HGNC
Official Full Name
NCK associated protein 5 likeprovided by HGNC
Primary source
HGNC:HGNC:29321
See related
Ensembl:ENSG00000167566 MIM:615104
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
Cep169; FP1193; KIAA1602
Expression
Ubiquitous expression in placenta (RPKM 5.5), testis (RPKM 5.4) and 25 other tissues See more
Orthologs

Genomic context

See NCKAP5L in Genome Data Viewer
Location:
12q13.12
Exon count:
14
Annotation release Status Assembly Chr Location
109.20200522 current GRCh38.p13 (GCF_000001405.39) 12 NC_000012.12 (49791139..49828750, complement)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 12 NC_000012.11 (50184929..50222208, complement)

Chromosome 12 - NC_000012.12Genomic Context describing neighboring genes Neighboring gene transmembrane BAX inhibitor motif containing 6 Neighboring gene LSM6 homolog, U6 small nuclear RNA and mRNA degradation associated pseudogene 2 Neighboring gene nuclear-encoded mitochondrial tRNA-Gln (TTG) 6-1 Neighboring gene BCDIN3D antisense RNA 1 Neighboring gene BCDIN3 domain containing RNA methyltransferase Neighboring gene ribosomal protein L35a pseudogene 28

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • FLJ36581, KIAA1602, MGC129863

Gene Ontology Provided by GOA

Function Evidence Code Pubs
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
microtubule bundle formation IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
microtubule bundle formation IDA
Inferred from Direct Assay
more info
PubMed 
microtubule depolymerization IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
microtubule depolymerization IMP
Inferred from Mutant Phenotype
more info
PubMed 
Component Evidence Code Pubs
centrosome IDA
Inferred from Direct Assay
more info
PubMed 
cytoplasm IEA
Inferred from Electronic Annotation
more info
 
microtubule plus-end IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
microtubule plus-end IDA
Inferred from Direct Assay
more info
PubMed 

General protein information

Preferred Names
nck-associated protein 5-like
Names
NCKAP5-like
centrosomal protein of 169 kDa

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001037806.4NP_001032895.2  nck-associated protein 5-like

    See identical proteins and their annotated locations for NP_001032895.2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Variants 1 and 2 both encode the same protein.
    Source sequence(s)
    AC131157, BC033253, BU617503, BX327000, CN359941, CN359946
    Consensus CDS
    CCDS41781.2
    UniProtKB/Swiss-Prot
    Q9HCH0
    Related
    ENSP00000337998.6, ENST00000335999.7
    Conserved Domains (1) summary
    pfam15246
    Location:8791183
    NCKAP5; Nck-associated protein 5, Peripheral clock protein
  2. NM_001368048.1NP_001354977.1  nck-associated protein 5-like

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longer transcript. Variants 1 and 2 both encode the same protein.
    Source sequence(s)
    AC131157

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000012.12 Reference GRCh38.p13 Primary Assembly

    Range
    49791139..49828750 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006719525.2XP_006719588.1  nck-associated protein 5-like isoform X1

    See identical proteins and their annotated locations for XP_006719588.1

    Conserved Domains (1) summary
    pfam15246
    Location:8791183
    NCKAP5; Nck-associated protein 5, Peripheral clock protein
  2. XM_011538611.2XP_011536913.1  nck-associated protein 5-like isoform X1

    See identical proteins and their annotated locations for XP_011536913.1

    Conserved Domains (1) summary
    pfam15246
    Location:8791183
    NCKAP5; Nck-associated protein 5, Peripheral clock protein
  3. XM_005269050.3XP_005269107.1  nck-associated protein 5-like isoform X2

    Conserved Domains (1) summary
    pfam15246
    Location:8791183
    NCKAP5; Nck-associated protein 5, Peripheral clock protein
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