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ZNF317 zinc finger protein 317 [ Homo sapiens (human) ]

Gene ID: 57693, updated on 1-Aug-2020

Summary

Official Symbol
ZNF317provided by HGNC
Official Full Name
zinc finger protein 317provided by HGNC
Primary source
HGNC:HGNC:13507
See related
Ensembl:ENSG00000130803 MIM:613864
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Expression
Ubiquitous expression in bone marrow (RPKM 11.1), lymph node (RPKM 7.9) and 25 other tissues See more
Orthologs

Genomic context

See ZNF317 in Genome Data Viewer
Location:
19p13.2
Exon count:
8
Annotation release Status Assembly Chr Location
109.20200522 current GRCh38.p13 (GCF_000001405.39) 19 NC_000019.10 (9140395..9163419)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 19 NC_000019.9 (9251056..9274091)

Chromosome 19 - NC_000019.10Genomic Context describing neighboring genes Neighboring gene olfactory receptor family 7 subfamily G member 15 pseudogene Neighboring gene olfactory receptor family 7 subfamily G member 3 Neighboring gene elongin C pseudogene 29 Neighboring gene olfactory receptor family 7 subfamily D member 2

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • KIAA1588

Gene Ontology Provided by GOA

Function Evidence Code Pubs
DNA binding IEA
Inferred from Electronic Annotation
more info
 
metal ion binding IEA
Inferred from Electronic Annotation
more info
 
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
regulation of transcription, DNA-templated IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
nucleus HDA PubMed 

General protein information

Preferred Names
zinc finger protein 317
Names
KRAB-containing zinc finger protein 317

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001190791.2NP_001177720.1  zinc finger protein 317 isoform 2

    See identical proteins and their annotated locations for NP_001177720.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) lacks an in-frame coding exon compared to variant 1. The resulting protein (isoform (2) is shorter but has the same N- and C-termini compared to isoform 1.
    Source sequence(s)
    AF148135, BC009367, DA757943
    Consensus CDS
    CCDS54213.1
    UniProtKB/Swiss-Prot
    Q96PQ6
    UniProtKB/TrEMBL
    A0A024R775
    Related
    ENSP00000353554.2, ENST00000360385.7
    Conserved Domains (5) summary
    smart00349
    Location:57103
    KRAB; krueppel associated box
    COG5048
    Location:190548
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:472492
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam01352
    Location:5796
    KRAB; KRAB box
    pfam13465
    Location:485508
    zf-H2C2_2; Zinc-finger double domain
  2. NM_020933.5NP_065984.3  zinc finger protein 317 isoform 1

    See identical proteins and their annotated locations for NP_065984.3

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) encodes the longer isoform (1).
    Source sequence(s)
    BC078154, DA757943
    Consensus CDS
    CCDS12210.1
    UniProtKB/Swiss-Prot
    Q96PQ6
    UniProtKB/TrEMBL
    A0A024R7B1
    Related
    ENSP00000247956.5, ENST00000247956.11
    Conserved Domains (3) summary
    smart00349
    Location:57109
    KRAB; krueppel associated box
    COG5048
    Location:222580
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:504524
    ZF_C2H2; C2H2 Zn finger [structural motif]

RNA

  1. NR_102435.2 RNA Sequence

    Status: VALIDATED

    Description
    Transcript Variant: This variant (3) uses an alternate splice site compared to variant 1. This variant is represented as non-coding because the use of the expected translational start codon, as used in variant 1, renders the transcript a candidate for nonsense-mediated mRNA decay (NMD).
    Source sequence(s)
    AC011464, BC009367
    Related
    ENST00000591278.5

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 109.20200522

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000019.10 Reference GRCh38.p13 Primary Assembly

    Range
    9140395..9163419
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_024451626.1XP_024307394.1  zinc finger protein 317 isoform X1

    Conserved Domains (3) summary
    smart00349
    Location:57109
    KRAB; krueppel associated box
    COG5048
    Location:222580
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:504524
    ZF_C2H2; C2H2 Zn finger [structural motif]

RNA

  1. XR_430146.4 RNA Sequence

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