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ZNF492 zinc finger protein 492 [ Homo sapiens (human) ]

Gene ID: 57615, updated on 25-Jan-2022

Summary

Official Symbol
ZNF492provided by HGNC
Official Full Name
zinc finger protein 492provided by HGNC
Primary source
HGNC:HGNC:23707
See related
Ensembl:ENSG00000229676 AllianceGenome:HGNC:23707
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
ZNF115
Summary
Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription, DNA-templated. Predicted to be located in nucleus. [provided by Alliance of Genome Resources, Nov 2021]
Expression
Broad expression in testis (RPKM 1.4), bone marrow (RPKM 0.9) and 16 other tissues See more
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Genomic context

See ZNF492 in Genome Data Viewer
Location:
19p12
Exon count:
4
Annotation release Status Assembly Chr Location
109.20211119 current GRCh38.p13 (GCF_000001405.39) 19 NC_000019.10 (22634324..22667671)
105.20201022 previous assembly GRCh37.p13 (GCF_000001405.25) 19 NC_000019.9 (22817126..22850473)

Chromosome 19 - NC_000019.10Genomic Context describing neighboring genes Neighboring gene RAD54L2 pseudogene 1 Neighboring gene long intergenic non-protein coding RNA 1785 Neighboring gene zinc finger protein 849, pseudogene Neighboring gene ribosomal protein L34 pseudogene 33

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Clone Names

  • KIAA1473, MGC129633, MGC148019

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables DNA-binding transcription factor activity, RNA polymerase II-specific IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in regulation of transcription by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
 
involved_in regulation of transcription, DNA-templated IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
zinc finger protein 492
Names
zinc finger protein 115 (Y20)

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_020855.3NP_065906.1  zinc finger protein 492

    See identical proteins and their annotated locations for NP_065906.1

    Status: VALIDATED

    Source sequence(s)
    AB040906, AC011467, BP871882
    Consensus CDS
    CCDS46032.1
    UniProtKB/Swiss-Prot
    Q9P255
    Related
    ENSP00000413660.2, ENST00000456783.3
    Conserved Domains (4) summary
    smart00349
    Location:132
    KRAB; krueppel associated box
    COG5048
    Location:138522
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:283303
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam13465
    Location:323348
    zf-H2C2_2; Zinc-finger double domain

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20211119

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000019.10 Reference GRCh38.p13 Primary Assembly

    Range
    22634324..22667671
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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