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ZNF471 zinc finger protein 471 [ Homo sapiens (human) ]

Gene ID: 57573, updated on 27-Nov-2024

Summary

Official Symbol
ZNF471provided by HGNC
Official Full Name
zinc finger protein 471provided by HGNC
Primary source
HGNC:HGNC:23226
See related
Ensembl:ENSG00000196263 MIM:620162; AllianceGenome:HGNC:23226
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
ERP1; Z1971; Zfp78
Summary
Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Located in nucleus. [provided by Alliance of Genome Resources, Nov 2024]
Expression
Ubiquitous expression in ovary (RPKM 3.7), endometrium (RPKM 2.7) and 24 other tissues See more
Orthologs
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Genomic context

See ZNF471 in Genome Data Viewer
Location:
19q13.43
Exon count:
5
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 19 NC_000019.10 (56507855..56530212)
RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 19 NC_060943.1 (59602138..59624646)
RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 19 NC_000019.9 (57019224..57041581)

Chromosome 19 - NC_000019.10Genomic Context describing neighboring genes Neighboring gene ZNF667 antisense RNA 1 (head to head) Neighboring gene uncharacterized LOC105372471 Neighboring gene uncharacterized LOC124904776 Neighboring gene P300/CBP strongly-dependent group 1 enhancer GRCh37_chr19:57037017-57038216 Neighboring gene ZFP28 divergent transcript Neighboring gene ZFP28 zinc finger protein Neighboring gene BRD4-independent group 4 enhancer GRCh37_chr19:57058653-57059852 Neighboring gene ZNF470 divergent transcript Neighboring gene P300/CBP strongly-dependent group 1 enhancer GRCh37_chr19:57065620-57066819 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 15120 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 15121 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 15122 Neighboring gene zinc finger protein 470

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Clone Names

  • KIAA1396, MGC150657, MGC150658

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables DNA-binding transcription factor activity, RNA polymerase II-specific IBA
Inferred from Biological aspect of Ancestor
more info
 
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
 
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
 
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
involved_in regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
 
Component Evidence Code Pubs
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in nucleus IDA
Inferred from Direct Assay
more info
 

General protein information

Preferred Names
zinc finger protein 471
Names
EZFIT-related protein 1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001321768.2NP_001308697.1  zinc finger protein 471 isoform 2

    Status: VALIDATED

    Source sequence(s)
    AC004696, AC005498, AI375847, AL831845, BM991696
    UniProtKB/Swiss-Prot
    Q9BX82
    Conserved Domains (3) summary
    COG5048
    Location:129536
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:443463
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam13465
    Location:483507
    zf-H2C2_2; Zinc-finger double domain
  2. NM_020813.4NP_065864.2  zinc finger protein 471 isoform 1

    See identical proteins and their annotated locations for NP_065864.2

    Status: VALIDATED

    Source sequence(s)
    AC005498, AI375847, AL831845, BC125221, BM991696
    Consensus CDS
    CCDS12945.1
    UniProtKB/Swiss-Prot
    B4DF32, O75260, Q08AD6, Q08AD7, Q8N3V1, Q9BX82, Q9P2F1
    Related
    ENSP00000309161.4, ENST00000308031.10
    Conserved Domains (5) summary
    smart00349
    Location:1473
    KRAB; krueppel associated box
    COG5048
    Location:203610
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:517537
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam01352
    Location:1453
    KRAB; KRAB box
    pfam13465
    Location:557581
    zf-H2C2_2; Zinc-finger double domain

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000019.10 Reference GRCh38.p14 Primary Assembly

    Range
    56507855..56530212
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011527148.2XP_011525450.1  zinc finger protein 471 isoform X1

    See identical proteins and their annotated locations for XP_011525450.1

    UniProtKB/Swiss-Prot
    B4DF32, O75260, Q08AD6, Q08AD7, Q8N3V1, Q9BX82, Q9P2F1
    Conserved Domains (5) summary
    smart00349
    Location:1473
    KRAB; krueppel associated box
    COG5048
    Location:203610
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:517537
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam01352
    Location:1453
    KRAB; KRAB box
    pfam13465
    Location:557581
    zf-H2C2_2; Zinc-finger double domain
  2. XM_047439129.1XP_047295085.1  zinc finger protein 471 isoform X1

    UniProtKB/Swiss-Prot
    B4DF32, O75260, Q08AD6, Q08AD7, Q8N3V1, Q9BX82, Q9P2F1
  3. XM_047439128.1XP_047295084.1  zinc finger protein 471 isoform X1

    UniProtKB/Swiss-Prot
    B4DF32, O75260, Q08AD6, Q08AD7, Q8N3V1, Q9BX82, Q9P2F1

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060943.1 Alternate T2T-CHM13v2.0

    Range
    59602138..59624646
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_054321541.1XP_054177516.1  zinc finger protein 471 isoform X1

  2. XM_054321542.1XP_054177517.1  zinc finger protein 471 isoform X1

  3. XM_054321543.1XP_054177518.1  zinc finger protein 471 isoform X1