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ZNF471 zinc finger protein 471 [ Homo sapiens (human) ]

Gene ID: 57573, updated on 2-Oct-2018

Summary

Official Symbol
ZNF471provided by HGNC
Official Full Name
zinc finger protein 471provided by HGNC
Primary source
HGNC:HGNC:23226
See related
Ensembl:ENSG00000196263 Vega:OTTHUMG00000181943
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
ERP1; Z1971
Expression
Ubiquitous expression in ovary (RPKM 3.7), endometrium (RPKM 2.7) and 24 other tissues See more
Orthologs

Genomic context

See ZNF471 in Genome Data Viewer
Location:
19q13.43
Exon count:
6
Annotation release Status Assembly Chr Location
109 current GRCh38.p12 (GCF_000001405.38) 19 NC_000019.10 (56507843..56530214)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 19 NC_000019.9 (57019212..57041581)

Chromosome 19 - NC_000019.10Genomic Context describing neighboring genes Neighboring gene zinc finger protein 667 Neighboring gene ZNF667 antisense RNA 1 (head to head) Neighboring gene uncharacterized LOC105372471 Neighboring gene uncharacterized LOC101928982 Neighboring gene uncharacterized LOC112268241 Neighboring gene ZFP28 zinc finger protein

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Jun 15 11:32:44 2016

Pathways from BioSystems

  • Gene Expression, organism-specific biosystem (from REACTOME)
    Gene Expression, organism-specific biosystemGene Expression covers the pathways by which genomic DNA is transcribed to yield RNA, the regulation of these transcription processes, and the pathways by which newly-made RNA Transcripts are process...
  • Generic Transcription Pathway, organism-specific biosystem (from REACTOME)
    Generic Transcription Pathway, organism-specific biosystemOVERVIEW OF TRANSCRIPTION REGULATION: Detailed studies of gene transcription regulation in a wide variety of eukaryotic systems has revealed the general principles and mechanisms by which cell- or t...

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • KIAA1396, MGC150657, MGC150658

Gene Ontology Provided by GOA

Function Evidence Code Pubs
DNA binding IEA
Inferred from Electronic Annotation
more info
 
DNA-binding transcription factor activity, RNA polymerase II-specific ISA
Inferred from Sequence Alignment
more info
 
metal ion binding IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
regulation of transcription by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
nucleus IDA
Inferred from Direct Assay
more info
 

General protein information

Preferred Names
zinc finger protein 471
Names
EZFIT-related protein 1

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001321768.1NP_001308697.1  zinc finger protein 471 isoform 2

    Status: VALIDATED

    Source sequence(s)
    AC004696, AC005498, AI375847, AL831845, BM991696
    UniProtKB/Swiss-Prot
    Q9BX82
    Conserved Domains (3) summary
    COG5048
    Location:129536
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:443463
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam13465
    Location:483507
    zf-H2C2_2; Zinc-finger double domain
  2. NM_020813.3NP_065864.2  zinc finger protein 471 isoform 1

    See identical proteins and their annotated locations for NP_065864.2

    Status: VALIDATED

    Source sequence(s)
    AC005498, AI375847, AL831845, BC125221, BM991696
    Consensus CDS
    CCDS12945.1
    UniProtKB/Swiss-Prot
    Q9BX82
    UniProtKB/TrEMBL
    A0A024R4Q9
    Related
    ENSP00000309161.4, OTTHUMP00000267952, ENST00000308031.9, OTTHUMT00000458405
    Conserved Domains (5) summary
    smart00349
    Location:1473
    KRAB; krueppel associated box
    COG5048
    Location:203610
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:517537
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam01352
    Location:1453
    KRAB; KRAB box
    pfam13465
    Location:557581
    zf-H2C2_2; Zinc-finger double domain

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p12 Primary Assembly

Genomic

  1. NC_000019.10 Reference GRCh38.p12 Primary Assembly

    Range
    56507843..56530214
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011527148.1XP_011525450.1  zinc finger protein 471 isoform X1

    See identical proteins and their annotated locations for XP_011525450.1

    UniProtKB/Swiss-Prot
    Q9BX82
    UniProtKB/TrEMBL
    A0A024R4Q9
    Conserved Domains (5) summary
    smart00349
    Location:1473
    KRAB; krueppel associated box
    COG5048
    Location:203610
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:517537
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam01352
    Location:1453
    KRAB; KRAB box
    pfam13465
    Location:557581
    zf-H2C2_2; Zinc-finger double domain
  2. XM_017027032.1XP_016882521.1  zinc finger protein 471 isoform X2

    Conserved Domains (3) summary
    COG5048
    Location:129536
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:443463
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam13465
    Location:483507
    zf-H2C2_2; Zinc-finger double domain
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