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DISP3 dispatched RND transporter family member 3 [ Homo sapiens (human) ]

Gene ID: 57540, updated on 12-Mar-2017
Official Symbol
DISP3provided by HGNC
Official Full Name
dispatched RND transporter family member 3provided by HGNC
Primary source
HGNC:HGNC:29251
See related
Ensembl:ENSG00000204624 MIM:611251; Vega:OTTHUMG00000002074
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
PTCHD2
Orthologs
Location:
1p36.22
Exon count:
24
Annotation release Status Assembly Chr Location
108 current GRCh38.p7 (GCF_000001405.33) 1 NC_000001.11 (11479155..11537583)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 1 NC_000001.10 (11539295..11597640)

Chromosome 1 - NC_000001.11Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC105376739 Neighboring gene uncharacterized LOC105376740 Neighboring gene long intergenic non-protein coding RNA 1647 Neighboring gene F-box protein 2 Neighboring gene F-box protein 44

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Jun 15 11:32:44 2016
Products Interactant Other Gene Complex Source Pubs Description

Markers

Homology

Clone Names

  • KIAA1337

Gene Ontology Provided by GOA

Function Evidence Code Pubs
molecular_function ND
No biological Data available
more info
 
Process Evidence Code Pubs
cholesterol homeostasis ISS
Inferred from Sequence or Structural Similarity
more info
PubMed 
cholesterol metabolic process IEA
Inferred from Electronic Annotation
more info
 
negative regulation of neuron differentiation IDA
Inferred from Direct Assay
more info
PubMed 
positive regulation of lipid metabolic process IDA
Inferred from Direct Assay
more info
PubMed 
positive regulation of neural precursor cell proliferation IDA
Inferred from Direct Assay
more info
PubMed 
regulation of lipid transport NAS
Non-traceable Author Statement
more info
PubMed 
smoothened signaling pathway NAS
Non-traceable Author Statement
more info
PubMed 
Component Evidence Code Pubs
cytoplasm IDA
Inferred from Direct Assay
more info
PubMed 
cytoplasmic vesicle membrane IEA
Inferred from Electronic Annotation
more info
 
endoplasmic reticulum ISS
Inferred from Sequence or Structural Similarity
more info
PubMed 
endoplasmic reticulum membrane IEA
Inferred from Electronic Annotation
more info
 
integral component of membrane NAS
Non-traceable Author Statement
more info
PubMed 
nuclear membrane ISS
Inferred from Sequence or Structural Similarity
more info
PubMed 
Preferred Names
protein dispatched homolog 3
Names
dispatched 3
dispatched homolog 3
patched domain containing 2
patched domain-containing protein 2

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_020780.1NP_065831.1  protein dispatched homolog 3

    See identical proteins and their annotated locations for NP_065831.1

    Status: VALIDATED

    Source sequence(s)
    AB037758, AL117236, AL590989, BU733859
    Consensus CDS
    CCDS41247.1
    UniProtKB/Swiss-Prot
    Q9P2K9
    Related
    ENSP00000294484, OTTHUMP00000002067, ENST00000294484, OTTHUMT00000005770
    Conserved Domains (3) summary
    pfam12235
    Location:148255
    FXMRP1_C_core; Fragile X-related 1 protein core C terminal
    cl01888
    Location:102170
    DUF883; Bacterial protein of unknown function (DUF883)
    cl21543
    Location:485615
    MMPL; MMPL family

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 108 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p7 Primary Assembly

Genomic

  1. NC_000001.11 Reference GRCh38.p7 Primary Assembly

    Range
    11479155..11537583
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011541830.2XP_011540132.1  protein dispatched homolog 3 isoform X3

    Conserved Domains (3) summary
    pfam12235
    Location:148255
    FXMRP1_C_core; Fragile X-related 1 protein core C terminal
    cl01888
    Location:102170
    DUF883; Bacterial protein of unknown function (DUF883)
    cl21543
    Location:485615
    MMPL; MMPL family
  2. XM_011541831.2XP_011540133.1  protein dispatched homolog 3 isoform X4

    Conserved Domains (3) summary
    pfam12235
    Location:148255
    FXMRP1_C_core; Fragile X-related 1 protein core C terminal
    cl01888
    Location:102170
    DUF883; Bacterial protein of unknown function (DUF883)
    cl21543
    Location:485615
    MMPL; MMPL family
  3. XM_011541832.2XP_011540134.1  protein dispatched homolog 3 isoform X5

    Conserved Domains (3) summary
    pfam12235
    Location:148255
    FXMRP1_C_core; Fragile X-related 1 protein core C terminal
    cl01888
    Location:102170
    DUF883; Bacterial protein of unknown function (DUF883)
    cl21543
    Location:485615
    MMPL; MMPL family
  4. XM_011541833.2XP_011540135.1  protein dispatched homolog 3 isoform X6

    Conserved Domains (3) summary
    pfam12235
    Location:148255
    FXMRP1_C_core; Fragile X-related 1 protein core C terminal
    cl01888
    Location:102170
    DUF883; Bacterial protein of unknown function (DUF883)
    cl21543
    Location:485615
    MMPL; MMPL family
  5. XM_011541835.2XP_011540137.1  protein dispatched homolog 3 isoform X7

    Conserved Domains (3) summary
    pfam12235
    Location:148255
    FXMRP1_C_core; Fragile X-related 1 protein core C terminal
    cl01888
    Location:102170
    DUF883; Bacterial protein of unknown function (DUF883)
    cl21543
    Location:485615
    MMPL; MMPL family
  6. XM_011541828.2XP_011540130.1  protein dispatched homolog 3 isoform X1

    See identical proteins and their annotated locations for XP_011540130.1

    UniProtKB/Swiss-Prot
    Q9P2K9
    Conserved Domains (3) summary
    pfam12235
    Location:148255
    FXMRP1_C_core; Fragile X-related 1 protein core C terminal
    cl01888
    Location:102170
    DUF883; Bacterial protein of unknown function (DUF883)
    cl21543
    Location:485615
    MMPL; MMPL family
  7. XM_011541829.1XP_011540131.1  protein dispatched homolog 3 isoform X2

    Conserved Domains (1) summary
    cl21543
    Location:114244
    MMPL; MMPL family

RNA

  1. XR_946717.2 RNA Sequence

  2. XR_001737342.1 RNA Sequence

Alternate CHM1_1.1

Genomic

  1. NC_018912.2 Alternate CHM1_1.1

    Range
    11527828..11585947
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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