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CGN cingulin [ Homo sapiens (human) ]

Gene ID: 57530, updated on 21-Dec-2019

Summary

Official Symbol
CGNprovided by HGNC
Official Full Name
cingulinprovided by HGNC
Primary source
HGNC:HGNC:17429
See related
Ensembl:ENSG00000143375 MIM:609473
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Expression
Broad expression in small intestine (RPKM 30.7), duodenum (RPKM 28.7) and 15 other tissues See more
Orthologs

Genomic context

See CGN in Genome Data Viewer
Location:
1q21.3
Exon count:
22
Annotation release Status Assembly Chr Location
109.20191205 current GRCh38.p13 (GCF_000001405.39) 1 NC_000001.11 (151510858..151538692)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 1 NC_000001.10 (151483331..151511168)

Chromosome 1 - NC_000001.11Genomic Context describing neighboring genes Neighboring gene proteasome 20S subunit beta 4 Neighboring gene pogo transposable element derived with ZNF domain Neighboring gene RNY4 pseudogene 25 Neighboring gene tuftelin 1 Neighboring gene microRNA 554 Neighboring gene ribosomal protein S10 pseudogene 6

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • FLJ39281, KIAA1319, DKFZp779N1112

Gene Ontology Provided by GOA

Function Evidence Code Pubs
actin binding ISS
Inferred from Sequence or Structural Similarity
more info
 
cadherin binding HDA PubMed 
motor activity IEA
Inferred from Electronic Annotation
more info
 
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
biological_process ND
No biological Data available
more info
 
transforming growth factor beta receptor signaling pathway TAS
Traceable Author Statement
more info
 
Component Evidence Code Pubs
bicellular tight junction IDA
Inferred from Direct Assay
more info
PubMed 
bicellular tight junction NAS
Non-traceable Author Statement
more info
PubMed 
cell junction IDA
Inferred from Direct Assay
more info
 
cell junction TAS
Traceable Author Statement
more info
 
myosin complex IEA
Inferred from Electronic Annotation
more info
 
plasma membrane IDA
Inferred from Direct Assay
more info
 

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_020770.3NP_065821.1  cingulin

    See identical proteins and their annotated locations for NP_065821.1

    Status: VALIDATED

    Source sequence(s)
    AF263462, AL365436, BC146657, BC152445, BP331021, CN359389
    Consensus CDS
    CCDS999.1
    UniProtKB/Swiss-Prot
    Q9P2M7
    Related
    ENSP00000271636.7, ENST00000271636.12
    Conserved Domains (1) summary
    cl25732
    Location:3681152
    SMC_N; RecF/RecN/SMC N terminal domain

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20191205

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000001.11 Reference GRCh38.p13 Primary Assembly

    Range
    151510858..151538692
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005245365.5XP_005245422.1  cingulin isoform X1

    See identical proteins and their annotated locations for XP_005245422.1

    UniProtKB/Swiss-Prot
    Q9P2M7
    Conserved Domains (1) summary
    cl25732
    Location:3681152
    SMC_N; RecF/RecN/SMC N terminal domain

RNA

  1. XR_921902.2 RNA Sequence

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