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RNF150 ring finger protein 150 [ Homo sapiens (human) ]

Gene ID: 57484, updated on 11-Jun-2021

Summary

Official Symbol
RNF150provided by HGNC
Official Full Name
ring finger protein 150provided by HGNC
Primary source
HGNC:HGNC:23138
See related
Ensembl:ENSG00000170153
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Expression
Broad expression in fat (RPKM 9.0), adrenal (RPKM 7.4) and 21 other tissues See more
Orthologs
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Genomic context

See RNF150 in Genome Data Viewer
Location:
4q31.21
Exon count:
11
Annotation release Status Assembly Chr Location
109.20210514 current GRCh38.p13 (GCF_000001405.39) 4 NC_000004.12 (140859807..141212858, complement)
105.20201022 previous assembly GRCh37.p13 (GCF_000001405.25) 4 NC_000004.11 (141780961..142054623, complement)

Chromosome 4 - NC_000004.12Genomic Context describing neighboring genes Neighboring gene TBC1 domain family member 9 Neighboring gene trinucleotide repeat containing 18 pseudogene 1 Neighboring gene RNY1 pseudogene 14 Neighboring gene zinc finger protein 330 Neighboring gene long intergenic non-protein coding RNA 2432

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Phenotypes

Associated conditions

Description Tests
Genome-wide association analysis of blood biomarkers in chronic obstructive pulmonary disease.
GeneReviews: Not available

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • MGC125502

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
 
enables ubiquitin protein ligase activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Process Evidence Code Pubs
involved_in protein ubiquitination IEA
Inferred from Electronic Annotation
more info
 
involved_in ubiquitin-dependent protein catabolic process IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in integral component of membrane IEA
Inferred from Electronic Annotation
more info
 

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_020724.2NP_065775.1  RING finger protein 150 precursor

    See identical proteins and their annotated locations for NP_065775.1

    Status: VALIDATED

    Source sequence(s)
    AB033040, AC093905, AC096733, AK130520
    Consensus CDS
    CCDS34065.1
    UniProtKB/Swiss-Prot
    Q9ULK6
    Related
    ENSP00000425840.1, ENST00000515673.7
    Conserved Domains (3) summary
    cd02122
    Location:45193
    PA_GRAIL_like; PA _GRAIL_like: Protease-associated (PA) domain GRAIL-like. This group includes PA domain containing E3 (ubiquitin ligases) similar to human GRAIL (gene related to anergy in lymphocytes) protein. Proteins in this group contain a C3H2C3 RING finger. E3 ...
    pfam13639
    Location:276319
    zf-RING_2; Ring finger domain
    cl11506
    Location:207232
    UPF0233; uncharacterized protein family (UPF0233)

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20210514

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000004.12 Reference GRCh38.p13 Primary Assembly

    Range
    140859807..141212858 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011532148.3XP_011530450.1  RING finger protein 150 isoform X3

    See identical proteins and their annotated locations for XP_011530450.1

    UniProtKB/Swiss-Prot
    Q9ULK6
    Related
    ENSP00000394581.2, ENST00000420921.6
    Conserved Domains (3) summary
    pfam13639
    Location:135178
    zf-RING_2; Ring finger domain
    cl10459
    Location:2052
    Peptidases_S8_S53; Peptidase domain in the S8 and S53 families
    cl11506
    Location:6691
    UPF0233; uncharacterized protein family (UPF0233)
  2. XM_005263150.5XP_005263207.1  RING finger protein 150 isoform X1

    Conserved Domains (3) summary
    cd02122
    Location:45215
    PA_GRAIL_like; PA _GRAIL_like: Protease-associated (PA) domain GRAIL-like. This group includes PA domain containing E3 (ubiquitin ligases) similar to human GRAIL (gene related to anergy in lymphocytes) protein. Proteins in this group contain a C3H2C3 RING finger. E3 ...
    pfam13639
    Location:298341
    zf-RING_2; Ring finger domain
    cl11506
    Location:229254
    UPF0233; uncharacterized protein family (UPF0233)
  3. XM_017008475.1XP_016863964.1  RING finger protein 150 isoform X4

  4. XM_011532147.2XP_011530449.1  RING finger protein 150 isoform X2

    Conserved Domains (3) summary
    pfam13639
    Location:148191
    zf-RING_2; Ring finger domain
    cl10459
    Location:3365
    Peptidases_S8_S53; Peptidase domain in the S8 and S53 families
    cl11506
    Location:79104
    UPF0233; uncharacterized protein family (UPF0233)
  5. XM_017008476.1XP_016863965.1  RING finger protein 150 isoform X5

    Related
    ENSP00000425947.2, ENST00000506101.2
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