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ZNF490 zinc finger protein 490 [ Homo sapiens (human) ]

Gene ID: 57474, updated on 12-Oct-2019

Summary

Official Symbol
ZNF490provided by HGNC
Official Full Name
zinc finger protein 490provided by HGNC
Primary source
HGNC:HGNC:23705
See related
Ensembl:ENSG00000188033
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Expression
Ubiquitous expression in thyroid (RPKM 1.3), spleen (RPKM 1.3) and 25 other tissues See more
Orthologs

Genomic context

See ZNF490 in Genome Data Viewer
Location:
19p13.2-p13.13
Exon count:
5
Annotation release Status Assembly Chr Location
109.20190905 current GRCh38.p13 (GCF_000001405.39) 19 NC_000019.10 (12576100..12610813, complement)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 19 NC_000019.9 (12686920..12721623, complement)

Chromosome 19 - NC_000019.10Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC105372278 Neighboring gene phosphoglycerate kinase 1, pseudogene 2 Neighboring gene vomeronasal 2 receptor 16 pseudogene Neighboring gene zinc finger protein 791 Neighboring gene uncharacterized LOC105372279 Neighboring gene ribosomal protein L10 pseudogene 16

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Phenotypes

NHGRI GWAS Catalog

Description
Propensity score-based nonparametric test revealing genetic variants underlying bipolar disorder.
NHGRI GWA Catalog

Pathways from BioSystems

  • Gene Expression, organism-specific biosystem (from REACTOME)
    Gene Expression, organism-specific biosystemGene Expression covers the pathways by which genomic DNA is transcribed to yield RNA, the regulation of these transcription processes, and the pathways by which newly-made RNA Transcripts are process...
  • Generic Transcription Pathway, organism-specific biosystem (from REACTOME)
    Generic Transcription Pathway, organism-specific biosystemOVERVIEW OF TRANSCRIPTION REGULATION: Detailed studies of gene transcription regulation in a wide variety of eukaryotic systems has revealed the general principles and mechanisms by which cell- or t...

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • KIAA1198

Gene Ontology Provided by GOA

Function Evidence Code Pubs
DNA binding IEA
Inferred from Electronic Annotation
more info
 
metal ion binding IEA
Inferred from Electronic Annotation
more info
 
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
regulation of transcription, DNA-templated IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
nucleus IEA
Inferred from Electronic Annotation
more info
 

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_020714.3NP_065765.1  zinc finger protein 490

    See identical proteins and their annotated locations for NP_065765.1

    Status: VALIDATED

    Source sequence(s)
    AB033024, AC010422
    Consensus CDS
    CCDS12272.1
    UniProtKB/Swiss-Prot
    Q9ULM2
    Related
    ENSP00000311521.6, ENST00000311437.11
    Conserved Domains (3) summary
    COG5048
    Location:192505
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:392412
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam01352
    Location:5697
    KRAB; KRAB box

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 109.20190905

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000019.10 Reference GRCh38.p13 Primary Assembly

    Range
    12576100..12610813 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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